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Letter to the editor regarding the publication “Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review”

Authors Jayaraj R, Kumarasamy C

Received 19 November 2018

Accepted for publication 13 December 2018

Published 24 January 2019 Volume 2019:11 Pages 1067—1068


Checked for plagiarism Yes

Editor who approved publication: Dr Ahmet Emre Eskazan

Rama Jayaraj,1 Chellan Kumarasamy2

1Clinical Sciences, College of Health and Human Sciences, Charles Darwin University, Casuarina, NT, Australia; 2University of Adelaide, Adelaide, SA, Australia

The authors of the article, “Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review”, Zhou et al, have put forth a number of interesting points.1 This paper, published in the journal Cancer Management and Research attempts to link matrix metalloproteinase (MMP) polymorphisms and the propensity to developing prostate cancer. Though a similar study has previously been done on ovarian cancer by authors credited in this study, this study does tread fresh ground on the topic of prostate cancer and has potential to act as a guideline for future research.
View the original paper by Zhou and colleagues.


The authors report no conflicts of interest in this communication.



Zhou H, Zhu X. Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review. Cancer Manag Res. 2018;10:5247–5259.


Weng H, Zeng XT, Wang XH, Liu TZ, He DL. Genetic association between Matrix Metalloproteinases gene polymorphisms and risk of prostate cancer: a meta-analysis. Front Physiol. 2017;8:975–975.


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