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Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say

Authors Sillo AJ, Makirita WE, Swai H, Chacha M

Received 17 September 2018

Accepted for publication 5 February 2019

Published 26 April 2019 Volume 2019:11 Pages 23—27

DOI https://doi.org/10.2147/JEP.S187837

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Professor Bal Lokeshwar


Video abstract presented by Albert J Sillo.

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Albert J Sillo, Winisia E Makirita, Hulda Swai, Musa Chacha

School of Life Sciences and Bio-Engineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania

Aim: This study aimed to evaluate larvicidal activity of Hypoestes forskaolii R. Br root extract against 3rd instar Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus.
Methods: A protocol developed by the World Health Organization was adopted, with minor modification using chloroform and methanol extracts with concentrations ranging from 25–750 μg/mL.
Results: The H. forskaolii chloroform extract exhibited very high larvicidal activity after 72 hours of exposure, with LC50 2.0322, 3.8989, 6.0004 μg/mL against A. gambiae, A. aegypti, and C. quinquefasciatus, respectively.
Conclusion: The larvicidal activity of H. forskaolii is reported for the first time in this paper. The effectiveness of H. forskaolii chloroform extract warrants further research to develop botanical mosquito repellants from this source.

Keywords: Hypoestes forskaolii, LC50, Anopheles gambiae, Aedes aegypti, Culex quinquefasciatus

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