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Lamellar macular holes: monitoring and management strategies

Authors Coassin M, Mori T, Di Zazzo A, Sgrulletta R, Varacalli G, Bonini S

Received 11 April 2019

Accepted for publication 17 June 2019

Published 9 July 2019 Volume 2019:13 Pages 1173—1182


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser

Marco Coassin, Tommaso Mori, Antonio Di Zazzo, Roberto Sgrulletta, Giuseppe Varacalli, Stefano Bonini

Department of Ophthalmology, University Campus Bio-Medico of Rome, Rome, Italy

Abstract: Lamellar macular holes are a vitreoretinal condition characterized by abnormalities in foveal contour with splitting of the neuroepithelium and often an intact photoreceptor layer. Recent developments in high-resolution imaging have increased our ability to study the details of the vitreoretinal interface and to distinguish between different forms of lamellar holes. A new classification is needed to help clinicians in the management of lamellar macular holes. Some clinicians prefer to observe these clinical entities, especially when visual acuity is maintained or alterations of the photoreceptor layer are present. Nevertheless, lamellar holes may sometimes progress, and visual acuity can deteriorate. On the other hand, surgical treatment may lead to positive anatomical and functional outcomes, but not without risks. This review provides a critical overview of the available data on lamellar macular holes, focusing on diagnosis and managing options.

Keywords: degenerative lamellar hole, tractional lamellar hole, lamellar hole-associated epiretinal proliferation, epiretinal membrane, vitrectomy, macular surgery

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