Back to Journals » OncoTargets and Therapy » Volume 6

Isolated epithelioid trophoblastic tumor of the vagina: a case report and review of the literature

Authors Zhao J, Xiang Y, Zhao D, Ren T, Feng F, Wan X

Received 26 June 2013

Accepted for publication 13 August 2013

Published 29 October 2013 Volume 2013:6 Pages 1523—1526


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Jing Zhao,1 Yang Xiang,1 Dachun Zhao,2 Tong Ren,1 Fengzhi Feng,1 Xirun Wan1

1Department of Obstetrics and Gynecology, 2Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China

Abstract: An epithelioid trophoblastic tumor (ETT) is a rare trophoblastic tumor originating from chorionic-type intermediate trophoblasts. Vaginal involvement in ETT in the form of isolated lesions has not been previously reported. A 43-year-old woman presented with vaginal wall cysts and was diagnosed with ETT by pathological examination after cystectomy. No clinical evidence of uterine involvement was found at diagnosis or during follow-up. The patient was treated with chemotherapy and surgery after the first recurrence and underwent follow-up for 8 months. The serum human chorionic gonadotropin titer remained at undetectable levels.

Keywords: ETT, isolated lesions, vaginal involvement

Creative Commons License © 2013 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.