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Intraocular pressure changes following the use of silicone oil or Densiron® 68 as endotamponade in pars plana vitrectomy

Authors Romano M, Angi M, Romano V, Parmeggiani, Campa C, Valldeperas X, Costagliola C

Published 26 November 2010 Volume 2010:4 Pages 1391—1396


Review by Single-blind

Peer reviewer comments 4

Mario R Romano1,2, Martina Angi3, Vito Romano1, Francesco Parmeggiani4, Claudio Campa4, Xavier Valldeperas5, Ciro Costagliola1
1Department of Health Sciences, Università del Molise, Campobasso, Italy; 2Department of Ophthalmology, Istituto Clinico Humanitas, Milan, Italy; 3Department of Ophthalmology, Campus-biomedico, Roma, Italy; 4Department of Ophthalmology, Università di Ferrara, Ferrara, Italy; 5Department of Ophthalmology, Hospital Germans Trias i Pujol, Badalona, Spain

Objective: To compare the effects of standard silicone oil 5700 (SSO) and heavy silicone oil (HSO) such as Densiron® 68 on intraocular pressure (IOP).
Materials and methods: Retrospective case series including 180 eyes (105 treated with SSO and 75 with HSO). IOP was measured before surgery, 1 day after, and then at 1-, 3-, 6-, and 12-month follow-ups.
Results: In the SSO group, a significant increase in IOP occurred in 14% of the eyes (15/105) at 1 day postoperatively, and persisted in 11.4% (12/105) at 1-month follow-up. In the HSO group, a persistent elevated IOP was recorded in 20% of the eyes (15/75) at 1 day postoperatively, and in 16% (12/75) at 1-month follow-up. At 12-month follow-up, mean IOP was 16.7 ± 8.7 mmHg and 19.7 ± 3.8 mmHg, respectively, in the SSO and HSO groups. The difference between the 2 groups was always not significant.
Conclusion: Overall, the use of Densiron 68 was not associated with higher IOP values as compared with SSO.

Keywords: Densiron 68, heavy silicone oil, silicone oil, intraocular pressure, vitrectomy

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