Back to Journals » Clinical Ophthalmology » Volume 8

Intensity of side effects of topical glaucoma medication and its influence on adherence behavior in patients with glaucoma

Authors Yu A, Weise S, Welge-Lussen U

Received 15 February 2014

Accepted for publication 5 April 2014

Published 28 June 2014 Volume 2014:8 Pages 1221—1226

DOI https://doi.org/10.2147/OPTH.S62494

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Alice L Yu,1 Stefanie Weise,2 Ulrich Welge-Lussen3

1Department of Ophthalmology, Ludwig-Maximilians-University, Munich, 2Department of Ophthalmology, University of Cologne, Cologne, 3Department of Ophthalmology, Friedrich-Alexander-University, Erlangen, Germany

Background: The aim of this study was to investigate the intensity of side effects that patients attribute to their topical glaucoma medication and their relationship to adherence behavior.
Methods: This was a questionnaire-based study of 123 glaucoma patients at a university eye clinic in Erlangen, Germany. An initial questionnaire asked about patient demographic data, the treatment plan, and intensity of side effects, and included Adherence to Refills and Medication Scale 2 (ARMS2) and visual analog scale (VAS-AD) scores. In a follow-up questionnaire, the treatment plan, intensity of side effects, ARMS2, and VAS-AD were reanalyzed.
Results: Most patients reported having few side effects, although only 20% said that they had no symptoms suggestive of side effects at all. The patients showed good adherence behavior on both the ARMS2 and VAS-AD scores, which were stable over time. The intensity of side effects experienced in the previous 7 days did not correlate with adherence scores and had no predictive value for adherence.
Conclusion: This study could not detect any significant influence of the subjectively experienced intensity of side effects on patients’ adherence behavior. However, we believe that a simple and clear treatment plan with few side effects is still preferred by most patients.

Keywords: adherence, side effects, eye drops, glaucoma

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]