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Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA

Authors Sutkowska E, Ostrowska M, Sutkowska M

Received 21 January 2021

Accepted for publication 4 March 2021

Published 9 April 2021 Volume 2021:14 Pages 1557—1561

DOI https://doi.org/10.2147/DMSO.S302874

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Antonio Brunetti


Edyta Sutkowska,1 Malgorzata Ostrowska,2 Magdalena Sutkowska3

1Medical Division, Department and Division of Medical Rehabilitation, Wroclaw Medical University, Wroclaw, Poland; 2Clinical Department of Nephrology and Dialysis Station, Karol Marcinkowski University Hospital, Zielona Gora, Poland; 3Medical Division, Wroclaw Medical University, Wroclaw, Poland

Correspondence: Edyta Sutkowska
Department and Division of Medical Rehabilitation, Wroclaw Medical University, Borowska 213, Wroclaw, 50-556, Poland
Tel +48 71 734 32 20
Email [email protected]

Abstract: Hypoglycemia presents relatively typical symptoms. However, when it occurs spontaneously – like in insulin autoimmune syndrome – it is difficult to perform scheduled biochemical tests at the laboratory. The study presents the case of a 31-year-old Caucasian female whose recurrent hypoglycemia symptoms were the reason for further diagnostics. The final results revealed a positive test for insulin autoantibody and glutamic acid decarboxylase autoantibody. Therefore, not only the potential causes of hypoglycemia but also an active autoimmune process typical for latent autoimmune diabetes in adults were confirmed. It was concluded that autoimmune hypoglycemia can be a part of the autoimmune process associated with diabetes and pre-diabetes in adults.

Keywords: autoimmune hypoglycemia, latent autoimmune diabetes, insulin autoantibodies, pre-clinical diabetes

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