Inhaled insulin for controlling blood glucose in patients with diabetes
Authors Bernard L Silverman, Christopher J Barnes, Barbara N Campaigne, Douglas B Muchmore
Published 15 January 2008 Volume 2007:3(6) Pages 947—958
Bernard L Silverman1, Christopher J Barnes2, Barbara N Campaigne3, Douglas B Muchmore3
1Alkermes, Inc, Cambridge, MA, USA; 2i3 Statprobe, Ann Arbor, MI; 3Eli Lilly and Company, Indianapolis, IN, USA
Abstract: Diabetes mellitus is a significant worldwide health problem, with the incidence of type 2 diabetes increasing at alarming rates. Insulin resistance and dysregulated blood glucose control are established risk factors for microvascular complications and cardiovascular disease. Despite the recognition of diabetes as a major health issue and the availability of a growing number of medications designed to counteract its detrimental effects, real and perceived barriers remain that prevent patients from achieving optimal blood glucose control. The development and utilization of inhaled insulin as a novel insulin delivery system may positively influence patient treatment adherence and optimal glycemic control, potentially leading to a reduction in cardiovascular complications in patients with diabetes.
Keywords: diabetes, inhaled insulin, cardiovascular disease, blood glucose