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Influence of cataract surgery and blood pressure changes caused by sodium restriction on retinal vascular diameter

Authors Takatoshi Tano, Yoshimune Hiratsuka, Koichi Ono, et al

Published 15 November 2010 Volume 2010:4 Pages 1299—1309

DOI https://doi.org/10.2147/OPTH.S14786

Review by Single-blind

Peer reviewer comments 3

Takatoshi Tano1, Yoshimune Hiratsuka2, Koichi Ono1, Akira Murakami1
1Department of Ophthalmology, Juntendo University School of Medicine, Tokyo; 2National Institute of Public Health, Tokyo, Japan

Purpose: To investigate the impact of cataract surgery and blood pressure changes induced by one week of sodium restriction on retinal vascular diameter.
Methods: Fundus photographs of 200 patients were obtained before and one week after cataract surgery. For one week after admission, 100 patients received sodium restriction and 100 patients (ie, the control group) did not receive sodium restriction. The diameter of the retinal vessels and blood pressure were compared between the sodium restriction group and the control group. The vascular diameter was measured using an objective computer-based method.
Results: Neither group had a significant change in the diameter of the retinal vessels after cataract surgery. Although there was no significant change in retinal arterial and venular diameter in the sodium restriction group, one-week sodium restriction significantly reduced mean blood pressure. However, multiple linear regression analyses indicated that an increase in retinal arteriolar diameter was significantly associated with diabetes, hyperlipidemia, and alcohol intake.
Conclusion: Cataract surgery and blood pressure reduction induced by one week of sodium restriction resulted in no significant change in retinal arteriolar diameter.

Keywords: cataract surgery, hypertension, retinal blood vessel diameter, retinal fundus camera, sodium restriction.

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