Back to Journals » Clinical Ophthalmology » Volume 7

Infectious endophthalmitis: review of 420 cases

Authors Bhoomibunchoo C, Ratanapakorn T, Sinawat S, Sanguansak T, Moontawee K, Yospaiboon Y

Received 4 November 2012

Accepted for publication 20 December 2012

Published 1 February 2013 Volume 2013:7 Pages 247—252


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Chavakij Bhoomibunchoo, Tanapat Ratanapakorn, Suthasinee Sinawat, Thuss Sanguansak, Kittipatra Moontawee, Yosanan Yospaiboon

Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

Background: To characterize the causative pathogens and the visual outcomes among patients with endophthalmitis at a large referral center in northeastern Thailand.
Methods: All cases of infectious endophthalmitis treated between 1983 and 2007 were reviewed retrospectively. The patient data – including age, sex, history of ocular injuries, previous treatment and duration of the symptoms – were recorded. The ocular examination included affected side, anterior chamber reaction, vitreous haze, and presence of intraocular foreign bodies. Smears and cultures were prepared from anterior chamber paracentesis and/or vitreous tapping. Intraocular antibiotics were administered at the time of anterior chamber paracentesis and/or vitreous tapping. Vitrectomy and/or lensectomy were performed when indicated. Initial visual acuity before treatment and the final best-corrected vision were compared.
Results: A total of 420 cases of endophthalmitis were reviewed: 181 cases (43.1%) had ocular trauma before the infection; 135 (32.2%) developed endophthalmitis after intraocular surgery; and, 122 (29.1%) had a positive culture. Bacteria were isolated in 114 cases (93.4%) and fungi were noted in eight (6.6%). The common causative bacterium was Staphylococcus epidermidis. Combined vitrectomy and intraocular antibiotics were performed in 189 cases (45.0%), whereas 69 cases (16.4%) were treated with intraocular antibiotics alone.
Conclusion: Most of the reviewed cases were associated with trauma and intraocular surgery. The most frequently encountered bacterium causing infectious endophthalmitis was S. epidermidis. Most cases were treated with combined vitrectomy and intraocular antibiotics. The final visual outcomes seem to vary according to the type of endophthalmitis.

Keywords: endophthalmitis, visual outcome, Staphylococcus epidermidis

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]


Other articles by this author:

Successful treatment of Chrysosporium keratitis with voriconazole

Thanathanee O, Bhoomibunchoo C, Anutarapongpan O, Suwan-apichon O, Yospaiboon Y

International Medical Case Reports Journal 2017, 10:93-95

Published Date: 20 March 2017

Systemic abnormalities associated with retinal vein occlusion in young patients

Sinawat S, Bunyavee C, Ratanapakorn T, Sinawat S, Laovirojjanakul W, Yospaiboon Y

Clinical Ophthalmology 2017, 11:441-447

Published Date: 23 February 2017

Idiopathic polypoidal choroidal vasculopathy in Thai patients with clinical and angiographic choroidal neovascularization

Bhoomibunchoo C, Yospaiboon Y, Thoongsuwan S, Rojanaporn D, Watanachai N, Jirarattanasopa P, Wongcumchang N, Amphornphruet A, Vongkulsiri S, Arayangkoon E

Clinical Ophthalmology 2017, 11:317-322

Published Date: 9 February 2017

Incidence of and risk factors for chloroquine and hydroxychloroquine retinopathy in Thai rheumatologic patients

Tangtavorn N, Yospaiboon Y, Ratanapakorn T, Sinawat S, Sanguansak T, Bhoomibunchoo C, Laovirojjanakul W

Clinical Ophthalmology 2016, 10:2179-2185

Published Date: 2 November 2016

Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy

Sanguansak T, Pitujaturont P, Yospaiboon Y, Sinawat S, Ratanapakorn T, Bhoomibunchoo C

Clinical Ophthalmology 2015, 9:2257-2261

Published Date: 1 December 2015

Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial

Thanathanee O, Ratanapakorn T, Morley MG, Yospaiboon Y

Clinical Ophthalmology 2012, 6:253-256

Published Date: 15 February 2012

Readers of this article also read:

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Prozorova GF, Pozdnyakov AS, Kuznetsova NP, Korzhova SA, Emel’yanov AI, Ermakova TG, Fadeeva TV, Sosedova LM

International Journal of Nanomedicine 2014, 9:1883-1889

Published Date: 16 April 2014

Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon

Ashwanikumar N, Kumar NA, Nair SA, Kumar GS

International Journal of Nanomedicine 2012, 7:5769-5779

Published Date: 15 November 2012

A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone

Hu Z, Liao M, Chen Y, Cai Y, Meng L, Liu Y, Lv N, Liu Z, Yuan W

International Journal of Nanomedicine 2012, 7:5719-5724

Published Date: 12 November 2012

Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy

Deepa G, Thulasidasan AK, Anto RJ, Pillai JJ, Kumar GS

International Journal of Nanomedicine 2012, 7:4077-4088

Published Date: 27 July 2012

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010