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Incidence rate and occurrence of visually significant cataract formation and corneal decompensation after implantation of Verisyse/Artisan phakic intraocular lens

Authors Moshirfar M, Imbornoni L, Ostler E, Muthappan V

Received 30 December 2013

Accepted for publication 4 February 2014

Published 8 April 2014 Volume 2014:8 Pages 711—716

DOI https://doi.org/10.2147/OPTH.S59878

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 5


Majid Moshirfar,1 Lauren M Imbornoni,2 Erik M Ostler,1 Valliammai Muthappan1

1Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA; 2University of Arizona College of Medicine, Tucson, AZ, USA

Purpose: To evaluate the incidence rate and indications for explantation of Verisyse phakic intraocular lenses (pIOLs) over a 13.6 year period.
Subjects and methods: Case series describing six cases of explantation of Verisyse pIOLs, out of 213 eyes with Verisyse pIOLs, implanted over a 13.6 year period by one surgeon at one institution, with mean follow-up of 5.6 years per eye.
Results: Four pIOLs were removed to facilitate extraction of a visually significant cataract, one was removed due to both cataract formation and development of corneal decompensation, and another was removed due to development of localized peripheral corneal decompensation. The incidence rate of pIOL removal was five per 1,000 patient-years with pIOL. Mean time from insertion of pIOL to cataract removal was 9.3 years (range 4.0–12.6 years). Mean time from insertion of pIOL to development of corneal decompensation was 10 years (range 6.9–13 years). There was no increase in the rate of cataract extraction in the pIOL population compared to the general population.
Conclusion: Cataracts may develop in patients with pIOLs, necessitating removal of the pIOL. Corneal decompensation is a serious complication that appears to be directly related to pIOLs. Corneal decompensation can occur up to 13 years following implantation of pIOLs, and long-term follow-up is important to monitor for this complication.

Keywords: Verisyse lens, Artisan lens, phakic IOL, corneal decompensation, cataract

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