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In vivo physiological research in the US: regulatory and ethical issues

Authors Cates C, Couto M

Received 18 August 2014

Accepted for publication 10 November 2014

Published 15 December 2014 Volume 2015:7 Pages 1—11

DOI https://doi.org/10.2147/OAAP.S51714

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Peter Koulen


Charles C Cates,1 Marcelo A Couto2

1Department of Comparative Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; 2Department of Laboratory Animal Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA

Abstract: Research using animals is a vital component to making life-saving discoveries in biology and health throughout the world. Research facilities face daily challenges in order to provide the utmost humane care and use of these precious animals. In the following paper, we examine five contemporary topics in regulatory and ethical management of laboratory animals: personhood of animals, chimpanzee use in research, contingency planning, freedom of information and open access laws, and social housing of research animals.

Keywords: chimpanzees, personhood of animals, social housing of research animals, contingency planning, FOIA


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