Importance of acute renal failure with ibuprofen
Sevket Yilmaz Training and Research Hospital, Geriatrics Unit, Yildirim, Bursa, Turkey
Kuptniratsaikul et al report the efficacy of Curcuma domestica extracts in the treatment of knee osteoarthritis.1 One of my concerns about this well designed study is lack of one important adverse event assessment. One of the most important adverse effects of ibuprofen, which is a non-selective non-steroid anti-inflammatory drug, is acute renal failure.2 Although one of the exclusion criteria in this study is renal failure, especially in the elderly population, it is crucial to follow up kidney functions under non-steroid anti-inflammatory treatment.
View original paper by Kuptniratsaikul and colleagues.
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