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Implantable cardioverter defibrillators: state of the art

Authors Ray J, Goodall H, Pascual T, Kusumoto F

Received 14 January 2015

Accepted for publication 9 February 2015

Published 7 April 2015 Volume 2015:6 Pages 29—41

DOI https://doi.org/10.2147/RRCC.S48339

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Richard Kones


Jordan C Ray, Harrison M Goodall, Thomas E Pascual, Fred M Kusumoto

Electrophysiology and Pacing Service, Division of Cardiovascular Disease, Department of Medicine, Mayo Clinic, Jacksonville, FL, USA


Abstract: It has been estimated that 180,000–450,000 people die suddenly in the US every year. Currently, the most effective method for reducing the risk of sudden death in those patients at highest risk is implantation of an internal cardioverter defibrillator (ICD). The evidence base for the benefit of the ICD has matured over the last two decades, and large studies have consistently shown reduced mortality or sudden cardiac death (SCD) in selected patient populations. Since its initial application in the early 1980s in patients who had already suffered an episode of SCD (secondary prevention), ICD use has expanded dramatically and now includes patients who are at high risk for a first event of SCD (primary prevention). More recent studies have focused on new technology, optimal programming, and other gaps in our understanding of the use of ICDs.

Keywords: sudden cardiac death, primary prevention, secondary prevention, myocardial infarction, ventricular fibrillation, ventricular tachycardia, LVEF, subcutaneous implantable cardioverter-defibrillator

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