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Impact of stent deployment pressure and poststenting dilatation on the outcome of elective percutaneous coronary intervention

Authors Nour M

Received 10 June 2016

Accepted for publication 1 August 2016

Published 12 September 2016 Volume 2016:7 Pages 109—116


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Richard Kones

Mahmoud K Nour

Department of Critical Care Medicine, Faculty of Medicine, Cairo University, Giza, Cairo, Egypt

Background: High-pressure stent deployment was proposed as a strategy that ensures complete stent apposition but its relation to outcome is markedly debated.
Objective: To verify the influence of stent deployment pressure and poststenting dilatation on the outcome of percutaneous coronary intervention.
We included 120 patients with single vessel coronary artery disease who were subjected to elective stenting. Patients were divided into two groups: group A, high deployment pressure ≥16 atm and group B, low deployment pressure 8–12 atm. Group B was subdivided into two subgroups according to whether patients underwent poststenting dilatation (subgroup B1) or not (subgroup B2). Clinical and angiographic 6-month follow-up was performed.
Results: The mean stent deployment pressure was higher in group A compared to group B (19±3 vs 10±2, P=0.01). There was no statistically significant difference found between groups A and B regarding major adverse cardiac events (16.7% vs 23.3%, P=0.404) including target lesion revascularization (5% vs 6.7%, P=0.970) and late loss (1.1 mm ±0.9 mm vs 1.22 mm ±0.85 mm, P=0.454), yet the restenosis rate was significantly lower in group A (23.3% vs 43.3%, P=0.032). Subgroup B1 showed a significantly lower restenosis rate compared to subgroup B2 (26.7% vs 60%, P=0.018), yet there was no significant difference between both subgroups regarding major cardiac adverse events (20% vs 26.7%, P=0.761).
Conclusion: High-pressure stent deployment was associated with significant reduction in the restenosis rate but not in the 6 months major adverse cardiac events. Poststenting dilatation resulted in a significantly lower restenosis rate when applied in the low-pressure stent deployment group.

Keywords: stent deployment pressure, major adverse cardiac events, restenosis

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