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Impact of multidisciplinary collaborative pharmaceutical care on knowledge, adherence, and efficacy of hormone therapy in climacteric women

Authors Lu M, Zhou Y, Wang BJ, Hu ZW, Du Y, Liu SF, Lin XF, Cui YM, Jin HY

Received 10 February 2018

Accepted for publication 20 April 2018

Published 19 July 2018 Volume 2018:12 Pages 1273—1278

DOI https://doi.org/10.2147/PPA.S165238

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Ms Justinn Cochran

Peer reviewer comments 2

Editor who approved publication: Dr Naifeng Liu


Min Lu,1 Ying Zhou,1 BaoJing Wang,2 ZheWen Hu,3 Ying Du,2 ShiFang Liu,2 XiuFeng Lin,2 YiMin Cui,1 HongYan Jin2

1Department of Pharmacy, Peking University First Hospital, Beijing, People’s Republic of China; 2Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, People’s Republic of China; 3Department of Nutrition, Peking University First Hospital, Beijing, People’s Republic of China

Background: The objective of this study was to evaluate the impact of pharmaceutical care on the knowledge, adherence, and efficacy of hormone therapy in climacteric women participated in multidisciplinary collaborative clinic, launched by Peking University First Hospital (Beijing, People’s Republic of China) in 2012.
Methods: A total of 296 patients were recruited (intervention group n=150, control group n=146). The patients in the intervention group visited the multidisciplinary collaborative clinic for their initial hormone therapy, receiving individualized pharmaceutical care (PC), whereas the control group visited only the general clinic without PC. The pill count method, knowledge assessment questionnaire (Cronbach’s α=0.80), and the modified Kupperman Index were used to assess the knowledge, adherence, and efficacy at months 3, 6, and 12.
Results: The intervention group, which received PC, showed significantly higher and better knowledge, adherence, and efficacy than the control group, demonstrating the effectiveness of the PC provided. The knowledge scores of the intervention and control groups at months 3, 6, and 12 were (73.12 vs 59.28), (77.63 vs 66.19), and (80.81 vs 66.64); the data for adherence were (90.97% vs 82.17%), (93.21% vs 87.79%), and (95.81% vs 93.38%); and the values of the modified Kupperman Index were (17.15 vs 24.05), (13.22 vs 22.01), and (12.21 vs 23.15), respectively.
Conclusion: PC improved the knowledge, adherence, and efficacy of hormone therapy in climacteric women. Therefore, the multidisciplinary collaborative model investigated in our study should be advocated in other health care institutions for the benefit of more patients. Further large-sample and long-term studies should be conducted to evaluate the effects of PC on patient clinical outcomes, including its impact on the safety and efficacy of long-term use of hormone therapy, as well as the economic benefits.

Keywords: pharmaceutical care, multidisciplinary collaborative care, menopausal women, hormone therapy

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