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Impact of Intraoperative Ocular Lubricants on Corneal Debridement Rate During Vitreoretinal Surgery

Authors Mathison ML, Li AS, Bao YK, Huang AJW, Rajagopal R

Received 10 October 2019

Accepted for publication 10 January 2020

Published 4 February 2020 Volume 2020:14 Pages 347—352

DOI https://doi.org/10.2147/OPTH.S234149

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Michael L Mathison,1 Albert S Li,1 Yicheng K Bao,2 Andrew JW Huang,1 Rithwick Rajagopal1

1Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, MO 63110, USA; 2Department of Medicine, University of Missouri — Kansas City School of Medicine, Kansas City, MO 64112, USA

Correspondence: Rithwick Rajagopal
Washington University School of Medicine, Campus Box 8096, 660 South Euclid Avenue, Saint Louis, MO 63110, USA
Tel +1 314 362 6929
Fax +1 314-362-2420
Email rajagopalr@wustl.edu

Purpose: To compare surgical parameters among patients receiving Viscoat (sodium chondroitin sulfate 4%–sodium hyaluronate 3%) or Goniosol (hydroxypropyl methylcellulose 2.5%) as topical lubricants for retinal surgery.
Methods: This was a retrospective analysis of patients undergoing retinal surgery between March 2013 and March 2018 using Goniosol or Viscoat as adjuvants. Primary outcome measures were rate of corneal debridement and operative time between groups, compared using χ2 and t-tests, respectively.
Results: Compared to Viscoat (n=319), the Goniosol group (n=210) had more frequent intraoperative corneal debridement (21.4% vs 0, p<0.05) and longer surgical times (98 vs 78 minutes, p<0.05). Patients in the Viscoat group had higher rates of complex procedures (34.8% vs 26.7%, p<0.05), but were younger (50.7 vs 55.0 years, p<0.05) and more likely to be phakic (83.4% vs 70.5%, p<0.05).
Conclusion: These findings suggest potential advantages of using Viscoat over Goniosol for corneal lubrication to aid visualization during vitreoretinal surgery.

Keywords: corneal epithelium, corneal debridement, corneal edema, Goniosol, Viscoat, vitreoretinal surgery


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