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Impact of Intraoperative Ocular Lubricants on Corneal Debridement Rate During Vitreoretinal Surgery
Authors Mathison ML, Li AS, Bao YK, Huang AJW, Rajagopal R
Received 10 October 2019
Accepted for publication 10 January 2020
Published 4 February 2020 Volume 2020:14 Pages 347—352
DOI https://doi.org/10.2147/OPTH.S234149
Checked for plagiarism Yes
Review by Single-blind
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Michael L Mathison,1 Albert S Li,1 Yicheng K Bao,2 Andrew JW Huang,1 Rithwick Rajagopal1
1Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, MO 63110, USA; 2Department of Medicine, University of Missouri — Kansas City School of Medicine, Kansas City, MO 64112, USA
Correspondence: Rithwick Rajagopal
Washington University School of Medicine, Campus Box 8096, 660 South Euclid Avenue, Saint Louis, MO 63110, USA
Tel +1 314 362 6929
Fax +1 314-362-2420
Email rajagopalr@wustl.edu
Purpose: To compare surgical parameters among patients receiving Viscoat (sodium chondroitin sulfate 4%–sodium hyaluronate 3%) or Goniosol (hydroxypropyl methylcellulose 2.5%) as topical lubricants for retinal surgery.
Methods: This was a retrospective analysis of patients undergoing retinal surgery between March 2013 and March 2018 using Goniosol or Viscoat as adjuvants. Primary outcome measures were rate of corneal debridement and operative time between groups, compared using χ2 and t-tests, respectively.
Results: Compared to Viscoat (n=319), the Goniosol group (n=210) had more frequent intraoperative corneal debridement (21.4% vs 0, p<0.05) and longer surgical times (98 vs 78 minutes, p<0.05). Patients in the Viscoat group had higher rates of complex procedures (34.8% vs 26.7%, p<0.05), but were younger (50.7 vs 55.0 years, p<0.05) and more likely to be phakic (83.4% vs 70.5%, p<0.05).
Conclusion: These findings suggest potential advantages of using Viscoat over Goniosol for corneal lubrication to aid visualization during vitreoretinal surgery.
Keywords: corneal epithelium, corneal debridement, corneal edema, Goniosol, Viscoat, vitreoretinal surgery
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