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Immunoglobulin transfusion in hemolytic disease of the newborn: place in therapy

Authors Mundy CA, Bhatia J

Received 18 January 2015

Accepted for publication 10 March 2015

Published 18 June 2015 Volume 2015:3 Pages 41—45


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Editor who approved publication: Prof. Dr. Cees Th. Smit Sibinga

Cynthia A Mundy, Jatinder Bhatia

Department of Pediatrics, Division of Neonatology, Georgia Regents University, Children's Hospital of Georgia, GA, USA

Abstract: Hemolytic disease of the newborn continues to be a common neonatal disorder that requires a comprehensive understanding on the part of those caring for infants. Common treatments include hydration and phototherapy. Exchange transfusion is used in severe hemolytic disease, but infants undergoing this treatment are exposed to many adverse effects. Intravenous immunoglobulin is a newer strategy that is showing promise in the treatment of the disease. This review discusses the current use and future expectations of intravenous immunoglobulin therapy in newborns.

Keywords: hyperbilirubinemia, ABO incompatibility, neonatal jaundice

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