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Idiopathic Hypereosinophilia and Venous Thromboembolism: Is There a Pathophysiological or Clinical Link? Description of an Intriguing Clinical Case

Authors Di Micco P, Scudiero O, scudiero O, Lombardo B, Lodigiani C

Received 29 August 2019

Accepted for publication 29 October 2019

Published 28 February 2020 Volume 2020:11 Pages 73—76


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Martin H. Bluth

Pierpaolo Di Micco,1 Olga Scudiero,2,3 Barbara Lombardo,2,3 Corrado Lodigiani4

1Department of Internal Medicine and Emergency Room, Fatebenefratelli Hospital of Naples, Naples, Italy; 2Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli “Federico II”, Napoli, Italia; 3CEINGE-Biotecnologie Avanzate, Napoli, Italia; 4Thrombosis and Hemorrhagic Center, Humanitas Research Hospital and Humanitas University, Rozzano, Italy

Correspondence: Corrado Lodigiani
Thrombosis and Hemorrhagic Center, Humanitas Research Hospital and Humanitas University, Rozzano, Italy

Abstract: Thrombosis events usually occur after prolonged bedrest, pregnancy, hormonal therapy, recent surgery and in the presence of inherited or acquired thrombophilia. However, several other diseases are often associated with thrombosis although their frequency is not easily estimated. Eosinophilia is one of these conditions. From a clinical viewpoint it is very difficult to understand which conditions might lead to a thrombotic event because the underlying pathophysiological mechanisms are different. Here, we report a case of idiopathic hypereosinophilia associated to venous thromboembolism without any other associated prothrombotic condition.

Keywords: venous thromboembolism, deep vein thrombosis, hypereosinophilia, allergy

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