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Identification of a seasonal pattern to brain metastases

Authors Sakellakis M, Koutras A, Pittaka M, Kardamakis D, Kalofonou M, Kalofonos H, Spyropoulou D

Received 14 January 2016

Accepted for publication 14 January 2016

Published 7 March 2016 Volume 2016:12 Pages 609—610


Checked for plagiarism Yes

Editor who approved publication: Dr Roger Pinder

Minas Sakellakis,1 Angelos Koutras,1 Maria Pittaka,2 Dimitrios Kardamakis,2 Melpomeni Kalofonou,1 Haralabos P Kalofonos,1 Despina Spyropoulou2

1Division of Oncology, Department of Medicine, 2Department of Radiation Oncology, University Hospital, Patras Medical School, Rion, Patras, Greece

We have previously tested our hypothesis that there is a seasonality in the incidence of carcinomatous meningitis.1 Although further validation is needed in a larger cohort, we found that leptomeningeal metastasis occurred more often during warm months of the year which, in the case of Greece, is the period generally marked with the larger daytime length.1 Carcinomatous meningitis is closely related to brain metastasis, and a logical question is whether warm season is marked by a greater propensity also for brain metastasis.2

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