Hypoperfusive and hypertensive ocular manifestations in Takayasu arteritis

Jayanthi Peter¹, Sarada David¹, George Joseph², Saban Horo¹, Debashish Danda<sup>3

1</sup>Department of Ophthalmology, Schell Eye Hospital, Vellore, India; ²Department of Cardiology, Christian Medical College Hospital, Vellore, India; ³Department of Clinical Immunology and Rheumatology, Christian Medical College Hospital, Vellore, India

Abstract: Takayasu arteritis is a relatively rare inflammatory arteritis that can be associated with ocular manifestations. We report four patients with proven Takayasu arteritis; two patients manifested hypoperfusive ocular manifestations of ocular ischemic syndrome and anterior ischemic optic neuropathy whilst two others had exudative retinal detachment and papilledema as a result of severe hypertension. The ischemic ocular manifestations were a result of hypoperfusion of the ocular structures due to occlusive arteritis of the aortic arch and its branches. The exudative retinal detachment and papilledema were manifestations of severe hypertension due to renal arterial involvement. Patients with Takayasu arteritis should be referred for ophthalmic assessment and screening for hypoperfusive and hypertensive manifestations.

Keywords: Takayasu, retinopathy, ocular ischemic syndrome, India

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