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How Common is Eosinophilia in Tuberculosis? Case Report

Authors Haftu H, Tadese K, Gebrehiwot T, Gebregziabher H

Received 31 December 2019

Accepted for publication 1 February 2020

Published 20 February 2020 Volume 2020:11 Pages 59—63


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Professor Roosy Aulakh

Hansa Haftu,1 Kibeten Tadese,2 Teklu Gebrehiwot,3 Hagos Gebregziabher4

1Mekelle University, College of Health Science, Pediatric and Child Health Department, Tigray, Ethiopia; 2Pediatric and Child Health Department, Tigray Regional Health Bureau, Tigray, Ethiopia; 3Mekelle University, College of Health Science, Clinical Pharmacist, Tigray, Ethiopia; 4Mekelle University, College of Health Science, Surgeon, Tigray, Ethiopia

Correspondence: Hansa Haftu Email

Abstract: Though peripheral blood eosinophilia is common due to allergic diseases, drugs, parasitic infections, and malignancies, it is rarely reported due to tuberculosis (TB). The association between eosinophilia and TB is not well known. We have a case of the 9-year-old female present with abdominal pain in the right upper quadrant which is non-radiating associated with decreased appetite, weight loss, malaise and low-grade fever and vomiting of ingested of two weeks. On examination, she had severe wasting and hepatomegaly. On investigations, she had leukocytosis with 50% of eosinophilia, high ESR, multiple liver cysts (abdominal ultrasound and CT) and biopsy suggestive of TB. Finally, the patient started on anti-TB and her response was followed by clinical and laboratory parameters. After three weeks of treatment with anti-TB, she starts to gain weight, improve abdominal pain, appetite loss, and the investigation also normalized (leukocyte and the eosinophil become normalized, ESR corrected). The patient was to follow up for two years in the clinic and finally discharged. The coexistence of eosinophilia and TB in our patient is suggested because of the biopsy results in conjunction with the improvement of peripheral blood eosinophilia with anti-TB treatment. This example hopefully will encourage future investigations and researchers to look at the prevalence and a clear association of TB and peripheral eosinophilia.

Keywords: tuberculosis, eosinophilia, liver

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