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Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity

Authors Shameli K, Ahmad MB, Yunis WZ, Rustaiyan A, Nor Azowa Ibrahim, Mohsen Z, Abdollahi Y

Published 22 October 2010 Volume 2010:5 Pages 875—887

DOI https://doi.org/10.2147/IJN.S13632

Review by Single-blind

Peer reviewer comments 2


Kamyar Shameli1, Mansor Bin Ahmad1, Wan Md Zin Wan Yunus1, Abdolhossein Rustaiyan2, Nor Azowa Ibrahim1, Mohsen Zargar3, Yadollah Abdollahi4
1Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 2Department of Chemistry, Science and Research Campus, Islamic Azad University, Tehran, Iran; 3Faculty of Food Science and Biotechnology, 4Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

Abstract: In this study, silver nanoparticles (Ag-NPs) were synthesized using a green physical synthetic route into the lamellar space of montmorillonite (MMT)/chitosan (Cts) utilizing the ultraviolet (UV) irradiation reduction method in the absence of any reducing agent or heat treatment. Cts, MMT, and AgNO3 were used as the natural polymeric stabilizer, solid support, and silver precursor, respectively. The properties of Ag/MMT/Cts bionanocomposites (BNCs) were studied as the function of UV irradiation times. UV irradiation disintegrated the Ag-NPs into smaller sizes until a relatively stable size and size distribution were achieved. Meanwhile, the crystalline structure and d-spacing of the MMT interlayer, average size and size distribution, surface morphology, elemental signal peaks, functional groups, and surface plasmon resonance of Ag/MMT/Cts BNCs were determined by powder X-ray diffraction, transmission electron microscopy, scanning electron microscopy, energy dispersive X-ray fluorescence, Fourier transform infrared, and UV-visible spectroscopy. The antibacterial activity of Ag-NPs in MMT/Cts was investigated against Gram-positive bacteria, ie, Staphylococcus aureus and methicillin-resistant S. aureus and Gram-negative bacteria (ie, Escherichia coli) by the disk diffusion method on Muller–Hinton Agar at different sizes of Ag-NPs. All of the synthesized Ag/MMT/Cts BNCs were found to have high antibacterial activity. These results show that Ag/MMT/Cts BNCs can be useful in different biologic research and biomedical applications, such as surgical devices and drug delivery vehicles.

Keywords: silver nanoparticles, bionanocomposites, montmorillonite, ultraviolet irradiation, chitosan, antibacterial activity

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