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Gastroesophageal reflux disease symptoms in the Greek general population: prevalence and risk factors

Authors Spantideas N, Drosou E, Bougea A, Assimakopoulos D

Received 2 January 2016

Accepted for publication 20 March 2016

Published 21 June 2016 Volume 2016:9 Pages 143—149

DOI https://doi.org/10.2147/CEG.S103485

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Yi Shen

Peer reviewer comments 2

Editor who approved publication: Professor Andreas M Kaiser


Nikolaos Spantideas,1 Eirini Drosou,1 Anastasia Bougea,2 Dimitrios Assimakopoulos,3

1Athens Speech Language and Swallowing Institute, Glyfada, Athens, Greece; 2Athens Speech Language and Swallowing Institute, Agios Dimitrios, Athens, Greece; 3Department of Otorhinolaryngology, Medical School of Ioannina University, University Hospital of Ioannina, Ioannina, Greece

Background and aims: Population-based data regarding the prevalence of gastroesophageal reflux disease (GERD) in Greece are very poor. This study estimated the prevalence of GERD symptoms and their risk factors in the Greek adult population.
Methods: A self-administered questionnaire was answered by a randomly selected population of 340 subjects. The question regarding “heartburn, chest pain, indigestion, or stomach acid coming up” as included in the Reflux Symptom Index was used for prevalence assessment.
Results: The monthly prevalence of GERD symptoms was found to be 52.0% in the Greek general population, with no statistically significant difference between the two sexes (P>0.05). The age group of 65–79 years showed a higher prevalence rate of GERD. Symptom severity was found to be mild (59.3%) or moderate (27.1%). The number of cigarettes smoked daily (but not smoking duration) as well as the number of alcoholic drinks consumed daily (but not the duration of alcohol drinking) were found to be related to GERD symptoms. No reported concomitant disease or medication was found to be related with GERD symptoms.
Conclusion: The prevalence of GERD symptoms in the Greek general population was found to be 52.0%. Tobacco smoking and alcohol drinking but not concomitant disease or medications were found to be related with GERD symptoms.

Keywords: gastroesophageal reflux, reflux, epidemiologic study, risk factors

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