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Gastric neuroendocrine tumors: management and challenges

Authors Kwon DH, Nakakura EK, Bergsland EK, Dai SC

Received 16 March 2017

Accepted for publication 2 August 2017

Published 29 September 2017 Volume 2017:7 Pages 31—37

DOI https://doi.org/10.2147/GICTT.S109028

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Akshita Wason

Peer reviewer comments 2

Editor who approved publication: Dr Eileen O'Reilly


Daniel H Kwon,1 Eric K Nakakura,2 Emily K Bergsland,3 Sun-Chuan Dai4

1Department of Medicine, 2Division of General Surgery, 3Division of Hematology/Oncology, 4Division of Gastroenterology, University of California San Francisco, San Francisco, CA, USA

Abstract: Gastric neuroendocrine tumors derive from enterochromaffin-like cells in the stomach mucosa. Based on histologic, serologic, and endoscopic findings, they may be further differentiated into types I, II, and III, with varying degrees of aggressiveness. In this article, diagnostic and classification strategies are reviewed, as are endoscopic, systemic, and surgical modalities for management. A multidisciplinary approach is advocated to provide the most effective patient care.

Keywords: neuroendocrine, tumor, carcinoid, gastrin, stomach

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