Gastric cancer in young people under 30 years of age: worse prognosis, or delay in diagnosis?
Authors López-Basave HN, Morales-Vásquez F, Ruiz-Molina JM, Ñamendys-Silva SA, Vela-Sarmiento I, Ruan J, Rosciano A, Calderillo-Ruiz G, Díaz-Romero C, Herrera-Gómez A, Meneses-García A
Received 15 November 2012
Accepted for publication 15 January 2013
Published 4 April 2013 Volume 2013:5 Pages 31—36
Checked for plagiarism Yes
Review by Single-blind
Peer reviewer comments 4
Horacio Noé López-Basave,1 Flavia Morales-Vásquez,2 Juan Manuel Ruiz-Molina,1 Silvio A Ñamendys-Silva,2 Itzel Vela-Sarmiento,1 Javier Melchor Ruan,1 Alejandro E Padilla Rosciano,1 German Calderillo-Ruiz,2 Consuelo Díaz-Romero,2 Angel Herrera-Gómez,1 Abelardo A Meneses-García3
1Departamento de Cirugía Oncológica, 2Departamento de Oncología Médica, 3Departamento de Terapia Intensiva, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico
Background: Gastric cancer is an aggressive disease with nonspecific early symptoms. Its incidence and prognosis in young patients has shown considerable variability.
Purpose of the study: Our objective was to retrospectively study patients from our institution aged <30 years with gastric carcinoma. The study was undertaken to describe the experience of gastric cancer in this population, and to demonstrate its specific clinical and pathological characteristics.
Materials and methods: We reviewed the cases of histologically confirmed gastric cancer between 1985 and 2006 at the Instituto Nacional de Cancerología of Mexico (INCan); emphasis in our review was placed on clinical presentation, diagnostic and therapeutic intervention, pathology, and the results.
Results: Thirty cases of gastric carcinoma were reviewed. The patients’ median age was 27 years (range, 18–30 years) and the male:female ratio was 1:1.
Conclusion: Gastric cancer exhibits different behavior in patients aged <30 years, but delay in diagnosis and the tumor’s behavior appear to be the most important factors in prognosis of the disease.
Keywords: gastric carcinoma, young people, delay in diagnosis
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