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Drug Design, Development and Therapy
ISSN: 1177-8881
- View all (4135)
- Volume 18, 2024 (96)
- Volume 17, 2023 (283)
- Volume 16, 2022 (316)
- Volume 15, 2021 (399)
- Volume 14, 2020 (477)
- Volume 13, 2019 (387)
- Volume 12, 2018 (382)
- Volume 11, 2017 (330)
- Volume 10, 2016 (374)
- Volume 9, 2015 (543)
- Volume 8, 2014 (231)
- Volume 7, 2013 (143)
- Volume 6, 2012 (42)
- Volume 5, 2011 (40)
- Volume 4, 2010 (35)
- Volume 3, 2009 (27)
- Volume 2, 2008 (29)
- Volume 1, 2007 (1)
Journal Articles:
- 4,135 records -
Dynasore Alleviates LPS-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis
Shan M, Wan H, Ran L, Ye J, Xie W, Lu J, Hu X, Deng S, Zhang W, Chen M, Wang F, Guo Z
Drug Design, Development and Therapy 2024, 18:1369-1384
Published Date: 23 April 2024
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug Design, Development and Therapy 2024, 18:1349-1368
Published Date: 23 April 2024
Effect of Fluid Therapy in Early Morning on the Incidence of Post-Induction Hypotension During Non-Cardiac Surgery After Noon: A Single-Center Retrospective Study
Zhang Y, Wang X, Sang X, Zhou Z, Dai G, Zhang X
Drug Design, Development and Therapy 2024, 18:1339-1347
Published Date: 22 April 2024
Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer
Chen S, Li M, Xue C, Zhou X, Wei J, Zheng L, Duan Y, Deng H, Tang F, Xiong W, Xiang B, Zhou M
Drug Design, Development and Therapy 2024, 18:1321-1338
Published Date: 23 April 2024
The Median Effective Dose of Intrathecal Hyperbaric Bupivacaine for Cesarean Section at Moderately High-Altitude
Yang C, Dong W, Luo J, Ma M, Gao Y, Ni L, Liu H, Cha C, Xiao Y, Huang S
Drug Design, Development and Therapy 2024, 18:1313-1319
Published Date: 22 April 2024
Natural and Synthetic Drugs Approached for the Treatment of Recurrent Aphthous Stomatitis Over the Last Decade
Vitamia C, Iftinan GN, Latarissa IR, Wilar G, Cahyanto A, Elamin KM, Wathoni N
Drug Design, Development and Therapy 2024, 18:1297-1312
Published Date: 22 April 2024
RNA-Based Antipsoriatic Gene Therapy: An Updated Review Focusing on Evidence from Animal Models
Lin ZC, Hung CF, Aljuffali IA, Lin MH, Fang JY
Drug Design, Development and Therapy 2024, 18:1277-1296
Published Date: 23 April 2024
Obacunone Alleviates Inflammatory Pain by Promoting M2 Microglial Polarization and by Activating Nrf2/HO-1 Signaling Pathway
Nan F, Tian Q, Chen S
Drug Design, Development and Therapy 2024, 18:1265-1275
Published Date: 18 April 2024
Cinnamaldehyde Inhibits the Function of Osteosarcoma by Suppressing the Wnt/β-Catenin and PI3K/Akt Signaling Pathways [Retraction]
Huang Y, Chen J, Yang S, Tan T, Wang N, Wang Y, Zhang L, Yang C, Huang H, Luo J, Luo X
Drug Design, Development and Therapy 2024, 18:1263-1264
Published Date: 18 April 2024
Sinomenine Hydrochloride Protects IgA Nephropathy Through Regulating Cell Growth and Apoptosis of T and B Lymphocytes
Li JJ, Li L, Li S, Tang XY, Sun HF, Liu JX
Drug Design, Development and Therapy 2024, 18:1247-1262
Published Date: 17 April 2024
Dexamethasone versus Dexmedetomidine as Adjuvants in Ultrasound Popliteal Sciatic Nerve Block for Hallux Valgus Surgery: A Mono-Centric Retrospective Comparative Study
Coviello A, Iacovazzo C, Cirillo D, Bernasconi A, Marra A, Squillacioti F, Martone M, Garone E, Coppola F, de Siena AU, Vargas M, Servillo G
Drug Design, Development and Therapy 2024, 18:1231-1245
Published Date: 17 April 2024
Clinical Application and Research Progress of Remimazolam for Pediatric Patients
Bai C, Xu M, Guo Y, Jin Y, Zhao X
Drug Design, Development and Therapy 2024, 18:1221-1229
Published Date: 17 April 2024
Network Pharmacology and Molecular Docking Identify the Potential Mechanism and Therapeutic Role of Scutellaria baicalensis in Alzheimer’s Disease
Peng Y, Zhou C
Drug Design, Development and Therapy 2024, 18:1199-1219
Published Date: 17 April 2024
Effect of S-Ketamine on Postoperative Nausea and Vomiting in Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trial
Qi Y, Zhou M, Zheng W, Dong Y, Li W, Wang L, Xu H, Zhang M, Yang D, Wang L, Zhou H
Drug Design, Development and Therapy 2024, 18:1189-1198
Published Date: 16 April 2024
A Novel Network Pharmacology Strategy Based on the Universal Effectiveness-Common Mechanism of Medical Herbs Uncovers Therapeutic Targets in Traumatic Brain Injury
Yu Z, Ding R, Yan Q, Cheng M, Li T, Zheng F, Zhu L, Wang Y, Tang T, Hu E
Drug Design, Development and Therapy 2024, 18:1175-1188
Published Date: 16 April 2024
Citric Acid Controls the Activity of YopH Bacterial Tyrosine Phosphatase
Styszko J, Kostrzewa T, Gorska-Ponikowska M, Kuban-Jankowska A
Drug Design, Development and Therapy 2024, 18:1165-1174
Published Date: 11 April 2024
Outcome of Darunavir–Cobicistat-Based Regimens in HIV-Infected People Who Have Experienced Virological Failure
Alberton F, Galli L, Lolatto R, Candela C, Gianotti N, Chiurlo M, Ranzenigo M, Strano M, Uglietti A, Castagna A
Drug Design, Development and Therapy 2024, 18:1153-1163
Published Date: 10 April 2024
The Promise of Therapeutic Psilocybin: An Evaluation of the 134 Clinical Trials, 54 Potential Indications, and 0 Marketing Approvals on ClinicalTrials.gov
Norring SA, Spigarelli MG
Drug Design, Development and Therapy 2024, 18:1143-1151
Published Date: 10 April 2024
Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats
Chayah M, Luque-González A, Gómez-Pérez V, Salagre D, Al-Shdaifat A, Campos JM, Conejo-García A, Agil A
Drug Design, Development and Therapy 2024, 18:1133-1141
Published Date: 10 April 2024
Unveiling the Mechanism of the ChaiShao Shugan Formula Against Triple-Negative Breast Cancer
Fan T, Huang Y, Liu Z, Huang J, Ke B, Rong Y, Qiu H, Zhang B
Drug Design, Development and Therapy 2024, 18:1115-1131
Published Date: 10 April 2024
Dexmedetomidine Prolongs Lidocaine Intravenous Regional Anesthesia in Rats by Blocking the Hyperpolarization-Activated Cation Current
Zhang T, Liao X, Chen Y, Shu X, Liu D, Yao Y
Drug Design, Development and Therapy 2024, 18:1103-1114
Published Date: 9 April 2024
Updated Evaluation of Agalsidase Alfa Enzyme Replacement Therapy for Patients with Fabry Disease: Insights from Real-World Data
Feriozzi S, Chimenti C, Reisin RC
Drug Design, Development and Therapy 2024, 18:1083-1101
Published Date: 3 April 2024
Mapping the Research of Ferroptosis in Parkinson’s Disease from 2013 to 2023: A Scientometric Review
Chen Y, Wu Z, Li S, Chen Q, Wang L, Qi X, Tian C, Yang M
Drug Design, Development and Therapy 2024, 18:1053-1081
Published Date: 3 April 2024
Molecular Modeling, Synthesis, and Antihyperglycemic Activity of the New Benzimidazole Derivatives – Imidazoline Receptor Agonists
Martynov A, Farber B, Bomko T, Beckles DL, Kleyn I
Drug Design, Development and Therapy 2024, 18:1035-1052
Published Date: 3 April 2024
Exploring the Median Effective Dose of Ciprofol for Anesthesia Induction in Elderly Patients: Impact of Frailty on ED50
Yuan J, Liang Z, Geoffrey MB, Xie Y, Chen S, Liu J, Xia Y, Li H, Zhao Y, Mao Y, Xing N, Yang J, Wang Z, Xing F
Drug Design, Development and Therapy 2024, 18:1025-1034
Published Date: 3 April 2024
Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling [LETTER]
Pasiana AD, Idrus HH, Purnamasari I
Drug Design, Development and Therapy 2024, 18:1023-1024
Published Date: 2 April 2024
The Emerging Roles of Nanocarrier Drug Delivery System in Treatment of Intervertebral Disc Degeneration-Current Knowledge, Hot Spots, Challenges and Future Perspectives
Hu Y, Yang R, Liu S, Song Z, Wang H
Drug Design, Development and Therapy 2024, 18:1007-1022
Published Date: 29 March 2024
Revolutionizing Stroke Recovery: Unveiling the Promise of Stem Cell Therapy
Panos LD, Bargiotas P, Arnold M, Hadjigeorgiou G, Panos GD
Drug Design, Development and Therapy 2024, 18:991-1006
Published Date: 29 March 2024
The Potential of Exosomes for Osteoporosis Treatment: A Review
He Y, Chen Y
Drug Design, Development and Therapy 2024, 18:979-989
Published Date: 28 March 2024
The Safety and Efficacy of Remimazolam Compared to Dexmedetomidine for Awake Tracheal Intubation by Flexible Bronchoscopy: A Randomized, Double-Blind, Controlled Trial
Chen Q, Qin B, Zhang M, Zhou Y, Shi X, Xie Y
Drug Design, Development and Therapy 2024, 18:967-978
Published Date: 28 March 2024
Neurophysiological Characteristics in Type II and Type III 5q Spinal Muscular Atrophy Patients: Impact of Nusinersen Treatment
Li D, Sun N, Xiang L, Liu J, Wang X, Yang L, Huang S
Drug Design, Development and Therapy 2024, 18:953-965
Published Date: 28 March 2024
A Review of Dupilumab in the Treatment of Atopic Dermatitis in Infants and Children
Wang M, Gao XH, Zhang L
Drug Design, Development and Therapy 2024, 18:941-951
Published Date: 27 March 2024
The Impact of Baohuoside I on the Metabolism of Tofacitinib in Rats
Shi Y, Lu Z, Song W, Wang Y, Zhou Q, Geng P, Zhou Y, Wang S, Han A
Drug Design, Development and Therapy 2024, 18:931-939
Published Date: 25 March 2024
Effect of Intraoperative infusion Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial
Xu H, Hao C, Wang X, Du J, Zhang T, Zhang X
Drug Design, Development and Therapy 2024, 18:919-929
Published Date: 25 March 2024
Intracranial Efficacy of Pyrotinib and Capecitabine Combination Therapy in HER2-Positive Breast Cancer with Brain Metastases
Wang C, Xiang J, Zhang Q, Li J, Liu Y, Liu J
Drug Design, Development and Therapy 2024, 18:909-917
Published Date: 23 March 2024
Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors
Youssef SH, Garg A, Song Y, Wylie NE, Garg S
Drug Design, Development and Therapy 2024, 18:899-908
Published Date: 22 March 2024
The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial
Wen T, Liu X, Pang T, Li M, Jiao G, Fan X, Tang J, Zhang C, Wang Z, Yue X, Chen W, Zhang F
Drug Design, Development and Therapy 2024, 18:881-897
Published Date: 21 March 2024
Optimal Once-Daily Busulfan Administration in Pediatric Patients: A Simulation-Based Investigation of Intravenous Infusion Times
Kim Y, Moon S, Rhee SJ
Drug Design, Development and Therapy 2024, 18:871-879
Published Date: 20 March 2024
A Novel DNA Aptamer Probe Recognizing Castration Resistant Prostate Cancer in vitro and in vivo Based on Cell-SELEX
Zhong J, Liu D, Yang Q, Ding J, Chen X
Drug Design, Development and Therapy 2024, 18:859-870
Published Date: 18 March 2024
Comparison of the Efficacy of Anti-Obesity Medications in Real-World Practice
Song JE, Ko HJ, Kim AS
Drug Design, Development and Therapy 2024, 18:845-858
Published Date: 18 March 2024
Understanding Sorafenib-Induced Cardiovascular Toxicity: Mechanisms and Treatment Implications
Li J, Zhang L, Ge T, Liu J, Wang C, Yu Q
Drug Design, Development and Therapy 2024, 18:829-843
Published Date: 18 March 2024
Development and Characterization of a Novel Carbon-11 Labeled Positron Emission Tomography Radiotracer for Neuroimaging of Sirtuin 1 with Benzoxazine-Based Compounds
Wang Y, Liu Y, Wang Y, Bai P, Hallisey MR, Varela BL, Siewko A, Wang C, Xu Y
Drug Design, Development and Therapy 2024, 18:819-827
Published Date: 15 March 2024
Model-Informed Precision Dosing of Isoniazid: Parametric Population Pharmacokinetics Model Repository
Ju G, Liu X, Yang W, Xu N, Chen L, Zhang C, He Q, Zhu X, Ouyang D
Drug Design, Development and Therapy 2024, 18:801-818
Published Date: 14 March 2024
Qifu Yixin Formula Improves Heart Failure by Enhancing β-Arrestin2 Mediated the SUMOylation of SERCA2a
Wang X, Yang J, Lu C, Hu Y, Xu Z, Wan Q, Zhang M, Shi T, Liu Z, Liu Y
Drug Design, Development and Therapy 2024, 18:781-799
Published Date: 11 March 2024
Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling
Liu J, Fang G, Lan C, Qiu C, Yao L, Zhang Q, Hu J, Zhang Y, Yang Y, Zhang Y
Drug Design, Development and Therapy 2024, 18:767-780
Published Date: 11 March 2024
Mechanisms of Action of Potentilla discolor Bunge in Type 2 Diabetes Mellitus Based on Network Pharmacology and Experimental Verification in Drosophila
Li Y, Wu F, Zhang J, Xu Y, Chang H, Yu Y, Jiang C, Gao X, Liu H, Chen Z, Wu C, Li JA
Drug Design, Development and Therapy 2024, 18:747-766
Published Date: 11 March 2024
Bibliometric and Visualization Analysis of Stem Cell Therapy for Erectile Dysfunction
Sun T, Liu Y, Yuan P, Jia Z, Yang J
Drug Design, Development and Therapy 2024, 18:731-746
Published Date: 8 March 2024
UHPLC-qTOF-MS-Based Nontargeted Metabolomics to Characterize the Effects of Capsaicin on Plasma and Skin Metabolic Profiles of C57BL/6 Mice-An In vivo Experimental Study
Xiao Z, Yu S, Zhang D, Li C
Drug Design, Development and Therapy 2024, 18:719-729
Published Date: 5 March 2024
Integrated Network Pharmacology and in vivo Experimental Validation Approach to Explore the Potential Antioxidant Effects of Annao Pingchong Decoction in Intracerebral Hemorrhage Rats
Zhou X, Wang X, Li J, Zhang M, Yang Y, Lei S, He Y, Yang H, Zhou D, Guo C
Drug Design, Development and Therapy 2024, 18:699-717
Published Date: 4 March 2024
Penehyclidine for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Gynecological Laparoscopic Surgery Under Combined Intravenous and Inhalation Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial
Zhao K, Gao Y, Zhang J, Wang S, Chen J, Guo F, Wang S
Drug Design, Development and Therapy 2024, 18:685-697
Published Date: 1 March 2024