open access to scientific and medical research

Back to Archived Journals » Journal of Receptor, Ligand and Channel Research » Volume 8

Review

Noteworthy comment: Despite the availability of several classes of drugs, migraine remains a difficult condition to treat effectively. This review provides an overview of three compounds : calcitonin gene related peptide (CGRP), brain natriuretic peptide (BNP) and ATP, whose intricate interactions contributes to the regulation of those neurons in the trigeminal system which generate the severe pain and other symptoms of migraine. Developing our knowledge of these compounds could lead to the generation of increasingly more effective drugs for the treatment of the condition.

Highly-accessed

Role of calcitonin gene-related peptide and brain natriuretic peptide to modulate the excitability state of trigeminal neurons: relevance to migraine pathology and treatment

Total article views		HTML views	PDF downloads	Totals
18,565	Dovepress*	18,565+	2,302	20,867
18,565	Totals	18,565	2,302	20,867
*Since 19 January 2015 +Since July 2016

View citations on Google Scholar