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Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study

Authors Theocharis I

Published 16 February 2010 Volume 2010:4 Pages 73—76

DOI https://doi.org/10.2147/OPTH.S8599

Review by Single-blind

Peer reviewer comments 2


IP Theocharis

Ophthalmology Department, Iaso General Hospital, Athens, Greece
Purpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).
Methods: FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;
Results: No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded.
Conclusions: FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.
Keywords: fibrinogen, retinal detachment, pathogenesis

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