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Factors influencing completion of treatment among pulmonary tuberculosis patients

Authors Fang XH, Dan YL, Liu J, Jun L, Zhang ZP, Kan XH, Ma DC, Wu GC

Received 12 December 2018

Accepted for publication 12 March 2019

Published 10 April 2019 Volume 2019:13 Pages 491—496

DOI https://doi.org/10.2147/PPA.S198007

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Johnny Chen


Xue-Hui Fang,1,* Yi-Lin Dan,2,* Jie Liu,1 Lei Jun,1 Zhi-Ping Zhang,3 Xiao-Hong Kan,1 Dong-Chun Ma,1 Guo-Cui Wu4

1Department of Science and Education, Anhui Provincial TB Institute, Hefei, Anhui, People’s Republic of China; 2Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People’s Republic of China; 3Department of Tuberculosis Prevention, Anqing Center for Disease Control and Prevention, Anqing, Anhui, People’s Republic of China; 4School of Nursing, Anhui Medical University, Hefei, Anhui, People’s Republic of China
 
*These authors contributed equally to this work
 
Objective: This study aimed to understand the influencing factors of treatment completion among pulmonary tuberculosis (PTB) patients in Anhui province, eastern People’s Republic of China, in order to provide scientific evidence for improving the follow-up rate and treatment completion rate.
Methods: A total of 262 PTB patients in six counties (districts) of Anhui province were investigated by questionnaire, and data about treatment interruption were collected.
Results: The main causes of treatment interruption were forgetting to take medicine (24.5%), drug side effects (23.3%), and symptomatic improvement (19.5%). The education background, patient type, cause of interruption, and tracking method were factors influencing completion of treatment (all P<0.05). The education level was positively associated with the treatment completion rate. New smear-positive patients had a significantly higher completion rate than others. The patients interrupted by drug side effects had the highest risk of interruption. In terms of the tracking method, the completion rate of patients tracked by the rural medical staff was significantly lower.
Conclusions: The management of PTB patients by medication supervision should be strengthened, especially for those with low education level and who had drug side effects, in order to improve their treatment completion rate.

Keywords: pulmonary tuberculosis, treatment completion, influencing factors

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