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Expert Consensus on Injection Technique and Area-Specific Recommendations for the Hyaluronic Acid Dermal Filler VYC-12L to Treat Fine Cutaneous Lines

Authors Ogilvie P, Thulesen J, Leys C, Sykianakis D, Chantrey J, Safa M, Figueiredo V, Heydenrych I, Cavallini M, Langeland EK, Wetter A

Received 22 November 2019

Accepted for publication 17 March 2020

Published 5 April 2020 Volume 2020:13 Pages 267—274


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Jeffrey Weinberg

Patricia Ogilvie, 1 Jesper Thulesen, 2 Christophe Leys, 3 Dimitris Sykianakis, 4 Jonquille Chantrey, 5 Marva Safa, 6 Vitor Figueiredo, 7 Izolda Heydenrych, 8 Maurizio Cavallini, 9 Elin Kringen Langeland, 10 Anne Wetter 11

1SkinConcept, Munich, Germany; 2Clinic Aesthetica, Copenhagen, Denmark; 3Medical Skincare, Sint-Truiden, Belgium; 4Well Aging Clinic, Athens, Greece; 5Expert Aesthetics, Cheshire, UK; 6La Jouvence, Neuchâtel, Switzerland; 7Up Clinic Lisboa, Lisbon, Portugal; 8Cosmetic Dermatology Centre, Cape Town, South Africa; 9Servizio di Chirurgia Plastica, Centro Diagnostico Italiano, Milan, Italy; 10Injeksjonsspesialisten AS, Trondheim, Norway; 11Diagnostiskt Centrum Hud, Stockholm, Sweden

Correspondence: Patricia Ogilvie
SkinConcept - Private Practice for Dermatology, Theatinerstraße 46, 80333 Munich, Germany
Tel +49 89 24214750

Background: VYC-12L is a hyaluronic acid (HA) injectable gel designed to treat fine cutaneous lines and improve skin quality attributes such as hydration and elasticity.
Objective: Expert consensus was sought on VYC-12L injection technique and primary treatment target areas.
Methods: A multinational group of aesthetic medicine clinicians (n = 128) attended product training and each identified ∼ 10 patients for VYC-12L. After treating their first and last patients, the clinicians completed a survey on preferred injection methodology/technique, including injection angle, volume, and spacing. An expert panel (n = 12) discussed survey results and their clinical experiences to obtain consensus on VYC-12L technique and appropriate treatment areas.
Results: Recommendations included micro-depot injections of VYC-12L into the deep dermis with a 32G ½ inch needle inserted at < 45º to the skin, spaced 0.5‒1.0 cm apart, with 0.01‒0.05 mL volume per injection (full-face total volume: ∼ 2 mL). Recommended primary treatment areas were the malar, perioral, neck, and décolletage regions. Injection techniques for different treatment areas/demographic characteristics were similar, with some variability in treatment approach. Patient selection criteria, pre- and post-treatment guidelines, and managing patient expectations are important components of treatment.
Conclusion: These consensus recommendations may assist clinicians in optimizing the treatment of fine lines with VYC-12L.

Keywords: consensus, hyaluronic acid, injectable dermal filler, dermis, skin aging, Juvéderm Volite

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