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Exogenous group G Streptococcus endophthalmitis following intravitreal ranibizumab injection

Authors Kugu S, Sevim MS, Kaymak NZ, Erdogan G, Kandemir, Dogan KO

Received 12 March 2012

Accepted for publication 19 May 2012

Published 28 August 2012 Volume 2012:6 Pages 1399—1402

DOI https://doi.org/10.2147/OPTH.S31721

Review by Single-blind

Peer reviewer comments 3


Suleyman Kugu,1 Mehmet Sahin Sevim,2 Nilufer Zorlutuna Kaymak,1 Gurkan Erdogan,3 Baran Kandemir,1 Omer Kamil Dogan4

1Lutfi Kirdar Kartal Training and Research Hospital, Eye Clinic, Istanbul, 2Haydarpasa Numune Training and Research Hospital, Eye Clinic, Istanbul, 3Umraniye Training and Research Hospital, Eye Clinic, Istanbul, 4World Eye Hospital, Eye Clinic, Istanbul, Turkey

Abstract: We report a case of group G Streptococcus endophthalmitis following an intravitreal ranibizumab injection for a choroidal neovascular membrane. Pars plana vitrectomy was applied for endophthalmitis and group G Streptococcus cultures were isolated in the vitreous samples taken from the patient. Twenty-four hours following pars plana vitrectomy the patient underwent myocardial infarction and cardiac arrest. To our knowledge this is the first reported case of group G Streptococcus endophthalmitis following an intravitreal injection.

Keywords: group G Streptococcus, endophthalmitis, intravitreal injection

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