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Everolimus-eluting stents in interventional cardiology

Authors Townsend JC, Rideout P, Steinberg DH

Received 28 January 2012

Accepted for publication 21 March 2012

Published 27 June 2012 Volume 2012:8 Pages 393—405

DOI https://dx.doi.org/10.2147/VHRM.S23388

Review by Single-blind

Peer reviewer comments 2

Jacob C Townsend, Phillip Rideout, Daniel H Steinberg
Division of Cardiology, Medical University of South Carolina, Charleston, SC, USA

Abstract: Bare metal stents have a proven safety record, but limited long-term efficacy due to in-stent restenosis. First-generation drug-eluting stents successfully countered the restenosis rate, but were hampered by concerns about their long-term safety. Second generation drug-eluting stents have combined the low restenosis rate of the first generation with improved long-term safety. We review the evolution of drug-eluting stents with a focus on the safety, efficacy, and unique characteristics of everolimus-eluting stents.

Keywords: everolimus-eluting stents, safety, efficacy

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