Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 7

Epidemiology of chronic obstructive pulmonary disease: a literature review

Authors Rycroft C, Heyes, Lanza L, Becker K

Received 28 March 2012

Accepted for publication 2 May 2012

Published 20 July 2012 Volume 2012:7 Pages 457—494


Review by Single-blind

Peer reviewer comments 2

Video abstract presented by Catherine Rycroft

Views: 834

Catherine E Rycroft,1 Anne Heyes,1 Lee Lanza,2 Karin Becker3

1Market Access and Outcomes Strategy, RTI Health Solutions, Manchester, United Kingdom; 2Epidemiology, RTI Health Solutions, Waltham, MA, USA; 3Global Health Economics and Outcomes Research, Boehringer Ingelheim GmbH, Ingelheim, Germany

Abstract: The aim of this study is to quantify the burden of chronic obstructive pulmonary disease (COPD) – incidence, prevalence, and mortality – and identify trends in Australia, Canada, France, Germany, Italy, Japan, The Netherlands, Spain, Sweden, the United Kingdom, and the United States of America. A structured literature search was performed (January 2000 to September 2010) of PubMed and EMBASE, identifying English-language articles reporting COPD prevalence, incidence, or mortality. Of 2838 articles identified, 299 full-text articles were reviewed, and data were extracted from 133 publications. Prevalence data were extracted from 80 articles, incidence data from 15 articles, and mortality data from 58 articles. Prevalence ranged from 0.2%–37%, but varied widely across countries and populations, and by COPD diagnosis and classification methods. Prevalence and incidence were greatest in men and those aged 75 years and older. Mortality ranged from 3–111 deaths per 100,000 population. Mortality increased in the last 30–40 years; more recently, mortality decreased in men in several countries, while increasing or stabilizing in women. Although COPD mortality increased over time, rates declined more recently, likely indicating improvements in COPD management. In many countries, COPD mortality has increased in women but decreased in men. This may be explained by differences in smoking patterns and a greater vulnerability in women to the adverse effects of smoking.

Keywords: COPD, incidence, literature review, mortality, prevalence

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]


Readers of this article also read:

Oxidative stress and antibacterial properties of a graphene oxide-cystamine nanohybrid

Nanda SS, An SS, Yi DK

International Journal of Nanomedicine 2015, 10:549-556

Published Date: 12 January 2015

IL-1α -889 C/T polymorphism and cancer susceptibility: a meta-analysis

Cheng D, Hao Y, Zhou W

OncoTargets and Therapy 2014, 7:2067-2074

Published Date: 10 November 2014

PTSD and comorbid AUD: a review of pharmacological and alternative treatment options

Ralevski E, Olivera-Figueroa LA, Petrakis I

Substance Abuse and Rehabilitation 2014, 5:25-36

Published Date: 7 March 2014

The prevalence of chronic fatigue syndrome/ myalgic encephalomyelitis: a meta-analysis

Johnston S, Brenu EW, Staines D, Marshall-Gradisnik S

Clinical Epidemiology 2013, 5:105-110

Published Date: 26 March 2013

Systematic review of persistent pain and psychological outcomes following traumatic musculoskeletal injury

Rosenbloom BN, Khan S, McCartney C, Katz J

Journal of Pain Research 2013, 6:39-51

Published Date: 10 January 2013

Exercise prescription for hospitalized people with chronic obstructive pulmonary disease and comorbidities: a synthesis of systematic reviews

Reid WD, Yamabayashi C, Goodridge D, Chung F, Hunt MA, Marciniuk DD, Brooks D, Chen YW, Hoens AM, Camp PG

International Journal of Chronic Obstructive Pulmonary Disease 2012, 7:297-320

Published Date: 14 May 2012