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Epidemiology and risk factors for invasive candidiasis

Authors Yapar N

Received 24 October 2013

Accepted for publication 16 December 2013

Published 13 February 2014 Volume 2014:10 Pages 95—105

DOI https://doi.org/10.2147/TCRM.S40160

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Nur Yapar

Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey

Abstract: The number of immunosuppressive patients has increased significantly in recent years. These patients are at risk for opportunistic infections, especially fungal infections. Candidiasis is one of the most frequent fungal infections determined in these immunosuppressive patients and its epidemiology has changed over the last two decades. Recently, new antifungal agents and new therapy strategies such as antifungal prophylaxis, secondary prophylaxis, and preemptive therapy have come into use. These changes resulted in the alteration of Candida species causing invasive infections. The incidence of Candida albicans was decreased in many countries, especially among patients with immunosuppressive disorders, while the incidence of species other than C. albicans was increased. In this review, incidence, risk factors, and species distribution of invasive candidiasis are discussed.

Keywords:
candidemia, invasive candidiasis, incidence, species distribution, risk factors

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