Back to Journals » International Journal of General Medicine » Volume 11

Epidemiological factors and worldwide pattern of Middle East respiratory syndrome coronavirus from 2013 to 2016

Authors Aghazadeh-Attari J, Mohebbi I, Mansorian B, Ahmadzadeh J, Mirza-Aghazadeh-Attari M, Mobaraki K, Oshnouei S

Received 24 December 2017

Accepted for publication 20 February 2018

Published 6 April 2018 Volume 2018:11 Pages 121—125


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser

Javad Aghazadeh-Attari,1 Iraj Mohebbi,2 Behnam Mansorian,2 Jamal Ahmadzadeh,1 Mohammad Mirza-Aghazadeh-Attari,3 Kazhal Mobaraki,1 Sima Oshnouei1

1Social Determinants of Health Research Center, Urmia University of Medical Sciences, Urmia, Iran; 2Social Determinants of Health Research Center, Occupational Medicine Center, Urmia University of Medical Sciences, Urmia, Iran; 3Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Background: Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging threat to global health security with high intensity and lethality. This study was conducted to investigate epidemiological factors and patterns related to this disease.
Methods: Full details of MERS-CoV cases available on the disease outbreak news section of the World Health Organization official website from January 2013 to November 2016 were retrieved; demographic and clinical information, global distribution status, potential contacts, and probable risk factors for the mortality of laboratory-confirmed MERS-CoV cases were extracted and analyzed by following standard statistical methods.
Results: Details of 1,094 laboratory-confirmed cases were recorded, including 421 related deaths. Significant differences were observed in the presentation of the disease from year to year, and all studied parameters differed during the years under study (all P-values <0.05). Evaluation of the effects of various potential risk factors of the final outcome (dead/survived) revealed that two factors, namely, the morbid case being native and travel history, are significant based on a unifactorial analysis (P <0.05). From 2013 to 2016, these factors remained important. However, factors that were significant in predicting mortality varied in different years.
Conclusion: These findings point to interesting potential dimensions in the dynamic of this disease. Furthermore, effective national and international preparedness plans and actions are essential to prevent, control, and predict such viral outbreaks; improve patient management; and ensure global health security.

Keywords: disease outbreaks, global health, MERS-CoV, risk factors, World Health Organization

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]