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Efficacy, safety and tolerability of combination therapy with timolol and dorzolamide in glaucoma and ocular hypertension

Authors Ichhpujani P, Katz LJ

Published 24 May 2010 Volume 2010:2 Pages 73—83

DOI https://doi.org/10.2147/DHPS.S9757

Review by Single-blind

Peer reviewer comments 4


Parul Ichhpujani1,2, L Jay Katz1

1William and Anna Goldberg Glaucoma Service, 1Wills Eye Institute, Philadelphia, PA, USA; 2Department of Ophthalmology, Government Medical College and Hospital, Chandigrah, India

Abstract: Combination pharmacotherapy has simplified and improved glaucoma medication regimens. This update focuses on the previous and recent studies on efficacy and tolerability profile of dorzolamide–timolol in adult ocular hypertension and open angle glaucoma patients. Dorzolamide–timolol has been shown to be efficacious and well tolerated in clinical trials and the adverse effects reflect those of the individual components.
Keywords: glaucoma, ocular hypertension, dorzolamide, timolol

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