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Effects of myrrh on intra-oral mucosal wounds compared with tetracycline- and chlorhexidine-based mouthwashes

Authors Al-Mobeeriek A

Published 30 August 2011 Volume 2011:3 Pages 53—58

DOI https://doi.org/10.2147/CCIDE.S24064

Review by Single-blind

Peer reviewer comments 4


Azizah Al-Mobeeriek
Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia

Aim: To evaluate the effect of myrrh compared with chlorhexidine gluconate- and tetracycline-containing mouthwashes on wound healing over time in an animal model.
Methods: A unilateral incision on the right buccal mucosa was made, and the wound was irrigated with myrrh-, chlorhexidine gluconate-, or tetracycline-based mouthwashes at various time intervals. Clinical and histological examination was performed for all the groups.
Results: It was found that the myrrh suspension promotes healing and repair of damaged tissue when used over a short period of time (less than 2 weeks) and in a low-concentration suspension; however, it can have harmful effects if used in excess or over a long period of time.
Conclusion: Further studies will also be required to study these effects and their mechanism of action in detail.

Keywords: myrrh, chlorhexidine gluconate, tetracycline, mouthwash, wound healing

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