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Effect of ultrasound-guided peripheral nerve blocks of the abdominal wall on pain relief after laparoscopic cholecystectomy

Authors Wu L, Wu L, Sun H, Dong C, Yu J

Received 31 January 2019

Accepted for publication 10 April 2019

Published 3 May 2019 Volume 2019:12 Pages 1433—1439


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Michael A Überall

Lining Wu, 1 Liangchun Wu, 2 Hao Sun, 1 Chunshan Dong, 1 Junma Yu 1

1Department of Anesthesiology, The First People’s Hospital of Hefei, Anhui Medical University, Hefei 230061, People’s Republic of China; 2Department of Anesthesiology, Anhui Provincial People‘s Armed Police General Hospital, Hefei 230041, People’s Republic of China

Purpose: The aim of this study was to compare the effect of an ultrasound-guided transversus abdominis plane block (TAPB) and rectus sheath block (RSB) combination, an ultrasound-guided posterior TAP block combined with the local anesthetic infiltration (LAI) and LAI alone on pain relief after laparoscopic cholecystectomy (LC).
Patients and methods: One hundred eighty patients who were American Society of Anesthesiologists class &Igr; or Π were included in this randomized, double-blind, non-inferiority study. All patients underwent three-port LC and were divided into 3 groups. The LAI group had ropivacaine mixed with dexmedetomidine injected around the trocar entrance site preoperatively. The TL group underwent ultrasound-guided posterior TAPB combined with LAI, and the TR group underwent ultrasound-guided TAPB combined with RSB. Postoperative pain was evaluated at the first, 4th, 8th, 24th, and 48th hours. If the visual analogue scale (VAS) score (including incisional pain, visceral pain or shoulder pain) was > 3, intravenous dezocine (0.05 mg/kg) was injected slowly. Sleep quality, total consumption of dezocine and time to unassisted walking were recorded. The Global Satisfaction Score (GSS) for analgesia was also assessed within 48 hrs.
Results: No difference was found in sleep quality, time to unassisted walking, or requirement for dezocine. We also found no difference in VAS scores at each time point within 48 hrs after LC among the 3 groups, but the GSS for analgesia in the LAI group was significantly increased within 48 hrs compared with the other two groups.
Conclusion: Ultrasound-guided peripheral nerve blocks of the abdominal wall can significantly relieve postoperative pain in patients undergoing LC; however, patients receiving LAI expressed more satisfaction than patients in whom other methods were used. LAI is an easy and effective method that can be recommended for routine clinical practice in LC patients who are not converted to an open procedure.

Keywords: laparoscopic cholecystectomy, postoperative pain, local anesthetics, TAPB, trocar-site anesthesia

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