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Effect of pharmaceutical care on clinical outcomes of outpatients with type 2 diabetes mellitus

Authors Shao H, Chen G, Zhu C, Chen Y, Liu Y, He Y, Jin H

Received 16 July 2015

Accepted for publication 28 February 2017

Published 8 May 2017 Volume 2017:11 Pages 897—903

DOI https://doi.org/10.2147/PPA.S92533

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Doris Leung

Peer reviewer comments 2

Editor who approved publication: Dr Naifeng Liu

Hua Shao,1 Guoming Chen,1 Chao Zhu,2 Yongfei Chen,1 Yamin Liu,1 Yuxing He,2 Hui Jin3

1Department of Pharmacy, Zhongda Hospital, School of Medicine, Southeast University, 2Department of Clinical Pharmacy, China Pharmaceutical University, 3Department of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People’s Republic of China


Background: In the People’s Republic of China, outpatients have limited time with their physicians. Thus, compared to inpatients, outpatients have lower medication adherence and are less knowledgeable about their disease.
Objective: The objective of this study was to evaluate the effect of pharmaceutical care on clinical outcomes of outpatients with type 2 diabetes mellitus (T2DM).
Patients and methods: A randomized, controlled, prospective clinical trial was conducted recruiting a total of 240 T2DM outpatients from Zhongda Hospital, Southeast University. ­The control group (CG) received only common care from medical staff, whereas the inter­vention group (IG) received extra pharmaceutical care from clinical pharmacists. Biochemical data such as blood pressure (BP), fasting blood glucose (FBG), glycosylated hemoglobin A1 (HbA1c), and blood lipid were collected before and after 6-month intervention. The primary end points in this study were FBG and HbA1c.
Results: After the intervention, most of the baseline clinical outcomes of the patients in IG significantly improved, while only body mass index, diastolic BP, low-density lipoprotein cholesterol, and total cholesterol (TC) improved significantly in patients in the CG. Compared to CG, in IG, there were significant improvements in FBG, HbA1c, TC, the target attainment rates of HbA1c, and BP.
Conclusion: Pharmaceutical care provided by clinical pharmacists could improve the control of diabetes of outpatients, and clinical pharmacists could play an important role in diabetes management.

Keywords: clinical pharmacist, pharmaceutical care, type 2 diabetes, outpatients

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