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Effect of cataract surgery on subfoveal choroidal and ganglion cell complex thicknesses measured by enhanced depth imaging optical coherence tomography

Authors Celik E, Cakir B, Turkoglu EB, Doğan E, Alagoz G

Received 7 February 2016

Accepted for publication 30 May 2016

Published 1 November 2016 Volume 2016:10 Pages 2171—2177

DOI https://doi.org/10.2147/OPTH.S105992

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Gokcen Gökçe

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Erkan Celik, Burcin Cakir, Elif Betul Turkoglu, Emine Doğan, Gursoy Alagoz

Sakarya University Medical Education and Research Hospital, Sakarya, Turkey

Purpose: We aimed to evaluate the effect of cataract surgery on subfoveal choroidal thickness (CT) and ganglion cell complex (GCC) thickness, as measured by enhanced depth imaging-optical coherence tomography (OCT).
Methods: This prospective study included 30 eyes of 30 patients who had undergone uneventful phacoemulsification surgery for senile cataract but had no previous ocular surgery or other ocular abnormality. Best-corrected visual acuity, slit-lamp biomicroscopy, intraocular pressure, axial length, and central corneal thickness were measured preoperatively. The operative times (OTs) and effective phaco times were also recorded in each case. OCT measurements were performed at the preoperative visit and 1 month after cataract surgery. Study of CT and GCC thickness changes was the primary objective, but central macular thickness (CMT) and peripapillary retinal nerve fiber layer (RNFL) thicknesses were also obtained by OCT.
Results: The mean subfoveal CT was 294.4±39.2 µm preoperatively and 301.4±39.9 µm postoperatively (P<0.001). The mean GCC thickness was 85.0±4.4 µm preoperatively and 89.2±5.3 µm postoperatively (P<0.001). The mean CMT was 247.9±17.6 µm preoperatively and 249.0±17.8 µm postoperatively (P=0.029). The mean RNFL thickness was 97.4±5.4 µm preoperatively and 101.7±5.6 µm postoperatively (P<0.001). Regression analysis showed that age, sex, axial length, central corneal thickness, operative time, and effective phaco time were not associated with CT changes (P=0.834, P=0.129, P=0.203, P=0.343, P=0.547, and P=0.147, respectively) and GCC thickness changes (P=0.645, P=0.542, P=0.152, P=0.664, P=0.448, and P=0.268, respectively) after cataract surgery.
Conclusion: Our results indicate that all subfoveal CT, CMT, as well as RNFL and GCC thicknesses are slightly affected after uneventful phacoemulsification surgery. After cataract surgery, the examiners should consider obtaining new baseline measurements.

Keywords: cataract, choroidal thickness, ganglion cell complex

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