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Editorial
Authors Bagel J
Published 23 June 2011 Volume 2011:1 Pages 1—2
Jerry Bagel
Psoriasis Treatment Center of Central New Jersey, East Windsor, NJ, USA
Twenty-five years ago, inpatient Goekerman therapy was considered to be the "gold standard" treatment for psoriasis. We thought PUVA (psoralen + ultraviolet A light) worked because it intercalated keratinocytes inhibiting cell division, methotrexate affected keratinocytic proliferation, and broadband ultraviolet B creating thymine dimers which also prevented keratinocytic proliferation. The idea that psoriasis was an immunologic disease was in its embryonic development.
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