Back to Journals » Psoriasis: Targets and Therapy » Volume 1

Editorial

Authors Bagel J

Published 23 June 2011 Volume 2011:1 Pages 1—2

DOI https://doi.org/10.2147/PTT.S21039


Jerry Bagel
Psoriasis Treatment Center of Central New Jersey, East Windsor, NJ, USA

Twenty-five years ago, inpatient Goekerman therapy was considered to be the "gold standard" treatment for psoriasis. We thought PUVA (psoralen + ultraviolet A light) worked because it intercalated keratinocytes inhibiting cell division, methotrexate affected keratinocytic proliferation, and broadband ultraviolet B creating thymine dimers which also prevented keratinocytic proliferation. The idea that psoriasis was an immunologic disease was in its embryonic development.

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