Double encephalitis with herpes simplex virus type II and cytomegalovirus in an elder Chinese: a case report

Chaobiao Xue,^1,2 Shaoxian Chen,¹ Qi Lin,¹ Houshi Zhou,¹ Chuming Huang,¹ Jiyuan Lin,¹ Weihang Xie,¹ Kai Chen,¹ Dongming Zhou,¹ Wan Ma,¹ Feiyu Ma,¹ Haiyun Xu<sup>2

1</sup>Outpatient Department, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, ²Mental Health Center, Shantou University Medical College, Shantou, Guangdong, People’s Republic of China

Abstract: Herpes simplex encephalitis is a rare disease. In adults, most of the reported cytomegalovirus (CMV) infections are seen in immunocompromised patients. We present a case of 67-year-old Chinese male with the coinfection of CMV and herpes simplex virus type II (HSV-II). He had no history of being treated with immunosuppressants, showed symptoms of psychosis and was scored 109 on the Positive and Negative Syndrome Scale. This patient presented with a rare case of coinfection of CMV and herpes simplex virus type II with psychotic symptoms.

Keywords: brain, viral coinfection, psychotic symptoms