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Does fesoterodine have a role in the treatment of poorly managed patients with overactive bladder?

Authors Morris V, Wagg A

Received 18 October 2013

Accepted for publication 13 November 2013

Published 9 January 2014 Volume 2014:8 Pages 113—119

DOI https://doi.org/10.2147/DDDT.S40032

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Vikky Morris,1 Adrian Wagg2

1Geriatric Medicine, Taunton Hospital Somerset, UK; 2Division of Geriatric Medicine, University of Alberta, Edmonton, Alberta, Canada

Abstract: Overactive bladder (OAB), a clinically defined symptom complex comprising urinary urgency, usually accompanied by urinary frequency and nocturia, with or without urgency incontinence, is common and has a markedly negative impact on the sufferer's quality of life. Following conservative and lifestyle management, the current pharmacological mainstay of treatment is antimuscarinic therapy. This review explores the role of fesoterodine, a relatively recently introduced antimuscarinic agent, in the treatment of patients who may have had a suboptimal response to initial therapy, who have switched treatment from tolterodine, or may be at risk of receiving poor treatment because of either multimorbidity or complex polypharmacy.

Keywords: elderly, fesoterodine, overactive bladder, urgency incontinence

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