Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis

Fouad Algendy A, Illigens B, Alyazeedi A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1563-1575

Published Date: 19 May 2022

Change in Metabolic Syndrome and Cardiorespiratory Fitness Following Exercise Training – The Ball State Adult Fitness Longitudinal Lifestyle Study (BALL ST)

Smith BE, Peterman JE, Harber MP, Imboden MT, Fleenor BS, Kaminsky LA, Whaley MH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1553-1562

Published Date: 20 May 2022

Hyperferritinemia Correlates to Metabolic Dysregulation and Steatosis in Chinese Biopsy-Proven Nonalcoholic Fatty Liver Disease Patients

Wang Q, Zhu M, Li H, Chen P, Wang M, Gu L, Zhang X, Chen L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1543-1552

Published Date: 17 May 2022

One-Hour Post-Load Plasma Glucose Levels are Associated with Early Arterial Stiffness in Subjects with Different Glucose Tolerance

Wang R, Liu XL, Jia XJ, Liu Y, Lu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1537-1542

Published Date: 17 May 2022

Association Between Obesity and COVID-19 Disease Severity in Saudi Population

Alqahtani FY, Aleanizy FS, Mohamed RAEH, Al-Maflehi N, Alrfaei BM, Almangour TA, Alkhudair N, Bawazeer G, Shamlan G, Alanazi MS

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1527-1535

Published Date: 16 May 2022

Usefulness of Exercise for Home Blood Pressure Control in People with Diabetes: A Study Protocol for a Crossover Randomized Controlled Trial [Corrigendum]

Iwai K, Ushigome E, Yokota I, Majima S, Nakanishi N, Hashimoto Y, Okada H, Senmaru T, Hamaguchi M, Asano M, Yamazaki M, Fukui M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1525-1526

Published Date: 16 May 2022

A Cross-Sectional Study of Serum Ferritin Levels in Vietnamese Adults with Metabolic Syndrome

Tran TN, Tran HD, Tran-Huu TT, Tran DM, Tran QN

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1517-1523

Published Date: 12 May 2022

The Perirenal Fat Thickness Was Associated with Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Yang Y, Li S, Xu Y, Ke J, Zhao D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1505-1515

Published Date: 11 May 2022

Real-World Analysis of Rapid-Acting Insulin Analog Use and Its Blood Glucose Lowering Effect in Patients with Type 2 Diabetes Mellitus: Results from PASSION Disease Registry in Korea

Kim HS, Yu JM, Jang HC, Choi EK, Park JH, Shon HS, Chung CH, Park KG, Cho JH, Kim W, Lee KH, Lee JH, Yoo SJ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1495-1503

Published Date: 11 May 2022

Diabetic Retinopathy as a Predictor of Angiographic Coronary Atherosclerosis Severity in Patients with Type 2 Diabetes Mellitus

Eid M, Mounir A, El Etriby S, Al Taher A, Ezzat MAW

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1485-1494

Published Date: 11 May 2022

Novel Insight into the Relationship Between Muscle-Fat and Bone in Type 2 Diabetes Ranging from Normal Weight to Obesity

Wang H, Peng H, Zhang L, Gao W, Ye J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1473-1484

Published Date: 10 May 2022

Relationship Between Four Non-Insulin-Based Indexes of Insulin Resistance and Serum Uric Acid in Patients with Type 2 Diabetes: A Cross-Sectional Study

Han R, Zhang Y, Jiang X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1461-1471

Published Date: 9 May 2022

If Not Insulin Resistance so What? – Comparison of Fasting Glycemia in Idiopathic Parkinson’s Disease and Atypical Parkinsonism

Chmiela T, Węgrzynek J, Kasprzyk A, Waksmundzki D, Wilczek D, Gorzkowska A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1451-1460

Published Date: 9 May 2022

Impaired Vascular Endothelial Function is Associated with Peripheral Neuropathy in Patients with Type 2 Diabetes

Li L, Yang Y, Bai J, Zhang Y, Yang H, Zhang Y, Lv H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1437-1449

Published Date: 6 May 2022

The Association Between Plasma Fatty Acid and Cognitive Function Mediated by Inflammation in Patients with Type 2 Diabetes Mellitus

Shen J, Yu H, Li K, Ding B, Xiao R, Ma W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1423-1436

Published Date: 6 May 2022

Association of the Coronavirus Disease 2019 Outbreak on the Diabetes Self-Management in Chinese Patients: An Analytical Cross-Sectional Study

Huang L, Zhang L, Jiang S, Liang B, Xu N, Li J, Zhang X, Zhang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1413-1422

Published Date: 6 May 2022

Review

The Role of PKM2 in Diabetic Microangiopathy

Tu C, Wang L, Wei L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1405-1412

Published Date: 4 May 2022

Placenta-Derived Exosomes and Gestational Diabetes Mellitus

Liu X, Qiu H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1391-1404

Published Date: 4 May 2022

Association of Nondiabetic Glucometabolic Status and Aortic Stiffness in Community Hypertension Patients [Letter]

Sayed Jaffar AlSharaf M, Harib AlDhmanie AA, Gopakumar A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1389-1390

Published Date: 3 May 2022

Clinical Characteristics, Glycemic Control, and Microvascular Complications Compared Between Young-Onset Type 1 and Type 2 Diabetes Patients at Siriraj Hospital – A Tertiary Referral Center

Preechasuk L, Tantasuwan S, Likitmaskul S, Santiprabhob J, Lertbannaphong O, Plengvidhya N, Tangjittipokin W, Nitiyanant W, Lertwattanarak R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1375-1387

Published Date: 2 May 2022

A Correlational Study on Cardiopulmonary Endurance in Male Patients with New-Onset Type 2 Diabetes

Liu BB, Niu ZR, Jia XJ, Liu XL, Lu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1365-1373

Published Date: 2 May 2022

Association Between Nocturnal Sleep Duration and Obesity Indicators Among People with Type 2 Diabetes: A Cross-Sectional Study in Ningbo, China

Xu M, Chattopadhyay K, Qian X, Li J, Li X, Sun J, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1357-1364

Published Date: 3 May 2022

A Retrospective Analysis of the Relationship Between 25-OH-Vitamin D and Diabetic Foot Ulcer

Wang F, Zhou L, Zhu D, Yang C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1347-1355

Published Date: 3 May 2022

Glucagon-Like Peptide 1 Receptor Agonist Improves Renal Tubular Damage in Mice with Diabetic Kidney Disease

Li R, She D, Ye Z, Fang P, Zong G, Zhao Y, Hu K, Zhang L, Lei S, Zhang K, Xue Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1331-1345

Published Date: 29 April 2022

The Inverse Association of Leg Fat Mass and Osteoporosis in Individuals with Type 2 Diabetes Independent of Lean Mass

Yang L, Deng H, Pan W, Huang X, Xu K, Zhang X, Hu X, Gu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1321-1330

Published Date: 29 April 2022

Adiponectin, May Be a Potential Protective Factor for Obesity-Related Osteoarthritis

Jiang H, Pu Y, Li ZH, Liu W, Deng Y, Liang R, Zhang XM, Zuo HD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1305-1319

Published Date: 27 April 2022

Clinical Features and Vitreous Biomarkers of Early-Onset Type 2 Diabetes Mellitus Complicated with Proliferative Diabetic Retinopathy

Ke D, Hong Y, Jiang X, Sun X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1293-1303

Published Date: 26 April 2022

Current Perspectives on Nonalcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome

Wang D, He B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1281-1291

Published Date: 24 April 2022

Evaluation of Dermatoglyphic Features of Type 2 Diabetic Patients as Compared to Non-Diabetics Attending Hospitals in Southern Ethiopia

Tadesse A, Gebremickael A, Merid M, Wondmagegn H, Melaku T, Ayele T, Meskele S, Esubalew H, Birhanu A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1269-1280

Published Date: 24 April 2022

Original Research

Does Hepatitis C Virus Treatment by Directly Acting Antivirals Obligate Shifting Patients with Type 2 Diabetes from Oral Hypoglycemic Drugs to Insulin Therapy?

Hagag RY, Selim AF, Darrag OM, Zied H, Aboelnasr MS

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1261-1268

Published Date: 26 April 2022

Autoimmune Polyendocrinopathy Induced by an Antibody (KN046) That Simultaneously Inhibits PD-L1 and CTLA-4: A Case Report and Literature Review

Li M, Wu C, Liu Y, Zhang R, Yang Q, Shi Z, Sun W, Hu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1253-1260

Published Date: 22 April 2022

Predictive Value of Plasma Atherogenic Index for Microalbuminuria in Newly Diagnosed Patients with Type 2 Diabetes Mellitus

Qi L, Kang N, Chen X, Li Z, Deng C, Chen S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1245-1252

Published Date: 21 April 2022

Efficacy of Emerging Technologies to Manage Childhood Obesity

Alotaibi M, Alnajjar F, Cappuccio M, Khalid S, Alhmiedat T, Mubin O

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1227-1244

Published Date: 21 April 2022

EAT Thickness as a Predominant Feature for Evaluating Arterial Stiffness in Patients with Heart Failure with Preserved Ejection Fraction

Liu Z, Hu W, Zhang H, Tao H, Lei P, Liu J, Yu Y, Dong Q, Gao L, Zhang D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1217-1226

Published Date: 21 April 2022

Melatonin Receptor 1B Genetic Variants on Susceptibility to Gestational Diabetes Mellitus: A Hospital-Based Case–Control Study in Wuhan, Central China

Liu J, Li W, Liu B, Dai A, Wang Y, She L, Zhang P, Zheng W, Dai Q, Yang M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1207-1216

Published Date: 20 April 2022

Sarcopenic Obesity with Normal Body Size May Have Higher Insulin Resistance in Elderly Patients with Type 2 Diabetes Mellitus

Han T, Yuan T, Liang X, Chen N, Song J, Zhao X, Weng Y, Hu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1197-1206

Published Date: 19 April 2022

The Relationship Between Depression and Multifactorial Control and Microvascular Complications in Vietnamese with Type 2 Diabetes Mellitus Aged 30–60 Years

Dinh Le T, Huy Duong H, Thi Nguyen L, Phi Thi Nguyen N, Tien Nguyen S, Van Ngo M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1185-1195

Published Date: 18 April 2022

Lipid-Lowering Responses to Dyslipidemia Determine the Efficacy on Liver Enzymes in Metabolic Dysfunction-Associated Fatty Liver Disease with Hepatic Injuries: A Prospective Cohort Study

Liao X, Ma Q, Wu T, Shao C, Lin Y, Sun Y, Feng S, Wang W, Ye J, Zhong B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1173-1184

Published Date: 18 April 2022

Preliminary Research of Main Components of Dll4/ Notch-VEGF Signaling Pathway Under High-Glucose Stimulation in vitro

Gao N, Xiao L, Tao Z, Zheng Y, Wang W, Huang H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1165-1171

Published Date: 18 April 2022

Down-Regulation of miR-138 Alleviates Inflammatory Response and Promotes Wound Healing in Diabetic Foot Ulcer Rats via Activating PI3K/AKT Pathway and hTERT

Wang J, Zhao X, Tian G, Liu X, Gui C, Xu L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1153-1163

Published Date: 14 April 2022

Association Between the Risk of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease

Zhao P, Yan J, Pan B, Liu J, Fu S, Cheng J, Wang L, Jing G, Li Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1141-1151

Published Date: 14 April 2022

The Impact of Intestinal Microorganisms and Their Metabolites on Type 1 Diabetes Mellitus

Zheng S, Luo Y, Xiao J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1123-1139

Published Date: 11 April 2022

The High Prevalence of Short-Term Elevation of Tumor Markers Due to Hyperglycemia in Diabetic Patients

Liu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1113-1122

Published Date: 11 April 2022

Statin Prescription Patterns and Associated Factors Among Patients with Type 2 Diabetes Mellitus Attending Diabetic Clinic at Muhimbili National Hospital, Dar es Salaam, Tanzania [Response to Letter]

Bideberi AT, Mutagaywa R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1111-1112

Published Date: 12 April 2022

Establishment and Validation of a Nomogram Model for Prediction of Diabetic Nephropathy in Type 2 Diabetic Patients with Proteinuria

Zhou DM, Wei J, Zhang TT, Shen FJ, Yang JK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1101-1110

Published Date: 8 April 2022

Assessment of Type II Diabetes Patients’ Caregivers’ Burnout Level: A Cross-Sectional Study in Taif, Saudi Arabia

Alsaedi YE, Almalki AA, Alqurashi RD, Altwairqi RS, Almalki DM, Alshehri KM, Alamri AA, Alswat KA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1091-1099

Published Date: 8 April 2022

Nomogram for Prediction of Diabetic Retinopathy Among Type 2 Diabetes Population in Xinjiang, China

Li Y, Li C, Zhao S, Yin Y, Zhang X, Wang K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1077-1089

Published Date: 7 April 2022

Development and Validation of a Simple Risk Model for Predicting Metabolic Syndrome (MetS) in Midlife: A Cohort Study

Ibrahim MS, Pang D, Randhawa G, Pappas Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1051-1075

Published Date: 6 April 2022

Free Triiodothyronine Levels are Related to Executive Function and Scene Memory in Type 2 Diabetes Mellitus Patients Without Diagnosed Thyroid Diseases

Zhang H, Yang S, Zhu W, Niu T, Wang Z, An K, Xie Z, Wang P, Huang X, Wang C, Shangguan H, Yuan Y, Wang S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1041-1050

Published Date: 5 April 2022

Modification Effect of Job Demand and Contingent Work Schedule on Overweight and Obesity Among Civil Servants in Taiwan

Tseng PC, Lin PY, Liang WM, Lin WY, Kuo HW

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1031-1039

Published Date: 5 April 2022

The Emerging Role of Dual GLP-1 and GIP Receptor Agonists in Glycemic Management and Cardiovascular Risk Reduction

Rizvi AA, Rizzo M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1023-1030

Published Date: 5 April 2022

Clinical Importance of FNDC-5 and Selectin-E mRNA Expression Among Type 2 Diabetics with and without Obesity

Verma AK, Aladel A, Dabeer S, Ahmad I, Khan MI, Almutairi MG, Al-Harbi AI, Beg MMA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1011-1021

Published Date: 2 April 2022

Feasibility of Virtual Simulation-Based Diabetes Foot Care Education in Patients with Diabetes in Ethiopia: Protocol for a Randomized Controlled Trial

Amdie FZ, Luctkar-Flude M, Snelgrove-Clarke E, Sawhney M, Alemu S, Woo K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:995-1009

Published Date: 31 March 2022

Prevalence and Associated Factors of Carpal Tunnel Syndrome Among Diabetic Patients in Arba Minch General Hospital, South West Ethiopia, 2021

Bekele A, Abebe G, Hailu T, Fekadu T, Gebremickael A, Getachew T, Churko C, Alelign D, Wassihun B, Teshome D, Bukala Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:983-993

Published Date: 31 March 2022

Associations of Thyroid Function Tests with Lipid Levels and Adverse Pregnancy Outcomes During the First Trimester

Liu WY, Zhu YT, Xu XM, Zhang JR, Gan XP, Cheng DC, Lu F, Lu C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:973-981

Published Date: 31 March 2022

Life-Course Influence of Adolescent Behaviour Problems on Type 2 Diabetes in Midlife: Results from 1958 British Birth Cohort Study

Saad SM, Iwundu C, Ibrahim MS, Randhawa G, Pang D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:963-972

Published Date: 29 March 2022

Potential Molecular Mechanism of Yishen Capsule in the Treatment of Diabetic Nephropathy Based on Network Pharmacology and Molecular Docking

Hu Y, Liu S, Liu W, Zhang Z, Liu Y, Li S, Sun D, Zhang G, Fang J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:943-962

Published Date: 29 March 2022

A Cross-Sectional Study of Atherosclerosis in Newly Diagnosed Patients with Ketosis-Prone Type 2 Diabetes

Wang Y, Lu C, Augusto Monteiro Cardoso Lopes M, Chen L, Luo Y, Wu W, Gu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:933-941

Published Date: 25 March 2022

Relationship Analysis of Inorganic Arsenic Exposure and Metabolic Syndrome Based on Propensity Score Matching in Xinjiang, China

Nie Y, Wang C, Yang L, Yang Z, Sun Y, Tian M, Ma Y, Zhang Y, Yuan Y, Zhang L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:921-931

Published Date: 25 March 2022

Eight Differential miRNAs in DN Identified by Microarray Analysis as Novel Biomarkers

Tu C, Wei L, Wang L, Tang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:907-920

Published Date: 24 March 2022

Influence of Carotid Intima-Media Thickness Levels at Bifurcation on Short-Term Functional Outcomes Among Non-Cardiogenic Ischemic Stroke Patients with and without Type 2 Diabetes Mellitus

Guo XJ, Wu M, Pei SF, Xie P, Wu MY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:897-906

Published Date: 23 March 2022

Relationship Between Thyroid Hormone and Liver Steatosis Analysis Parameter in Obese Participants: A Case-Control Study

Chen S, Jin Y, Xu M, Zhang P, Zhou Y, Qian X, Song Q, Bu S, Sun J, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:887-896

Published Date: 22 March 2022

Association of ADIPOQ Single-Nucleotide Polymorphisms with the Two Clinical Phenotypes Type 2 Diabetes Mellitus and Metabolic Syndromein a Kinh Vietnamese Population [Corrigendum]

Truong S, Tran NQ, Ma PT, Hoang CK, Le BH, Dinh T, Tran L, Tran TV, Gia Le LH, Vu HA, Mai TP, Do MD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:885-886

Published Date: 21 March 2022

Evaluation of the Thyroid Characteristics and Correlated Factors in Hospitalized Patients with Newly Diagnosed Type 2 Diabetes

Li Y, Yi M, Deng X, Li W, Chen Y, Zhang X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:873-884

Published Date: 20 March 2022

Association Between Elevated Thyroid Peroxidase Antibody and Abdominal Fat Distribution in Patients with Type 2 Diabetes Mellitus

Hu Y, Zheng J, Ye X, Song Y, Wu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:863-871

Published Date: 17 March 2022

Adipose Dysfunction in Adulthood Insulin Resistance of Low-Birth Weight Mice: A Proteomics Study

Wang J, Yang L, Yang L, Zhou F, Zhao H, Liu J, Ma H, Song G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:849-862

Published Date: 16 March 2022

Metabolic Syndrome Components and Chronic Kidney Disease in a Community Population Aged 40 Years and Older in Southern China: A Cross-Sectional Study

Xiao H, Shao X, Gao P, Zou H, Zhang X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:839-848

Published Date: 16 March 2022

Relationship Between Muscle Cramps and Diabetic Retinopathy in Patients with Type 2 Diabetes

Huiqing Hu, Wang C, Liang K, He Q, Song J, Guo X, Hou X, Chen L, Yan F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:827-837

Published Date: 15 March 2022

Sex-Specific Associations Between Serum Phosphate Concentration and Cardiometabolic Disease: A Cohort Study on the Community-Based Older Chinese Population

Lan Q, Zhang Y, Lin F, Meng Q, Buys N, Fan H, Sun J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:813-826

Published Date: 15 March 2022

Development and External Validation of a Nomogram and a Risk Table for Prediction of Type 2 Diabetic Kidney Disease Progression Based on a Retrospective Cohort Study in China

Gao YM, Feng ST, Yang Y, Li ZL, Wen Y, Wang B, Lv LL, Xing GL, Liu BC

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:799-811

Published Date: 14 March 2022

The Comparative Study on the Status of Bone Metabolism and Thyroid Function in Diabetic Patients with or without Ketosis or Ketoacidosis

Xu C, Gong M, Wen S, Zhou M, Li Y, Zhou L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:779-797

Published Date: 12 March 2022

Liver Enzymes and Non-Alcoholic Fatty Liver Disease: Important Factors in Assessing Patterns of Clinical Management in Type-2 Diabetes Patients [Letter]

Moeed A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:777-778

Published Date: 8 March 2022

Protein Intake Among Patients with Insulin-Treated Diabetes is Linked to Poor Glycemic Control: Findings of NHANES Data

Bawadi H, Al-Bayyari N, Tayyem R, Shi Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:767-775

Published Date: 8 March 2022

Compositional Alterations of Gut Microbiota in Patients with Diabetic Kidney Disease and Type 2 Diabetes Mellitus

He X, Sun J, Liu C, Yu X, Li H, Zhang W, Li Y, Geng Y, Wang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:755-765

Published Date: 6 March 2022

Metabolic Syndrome During Pregnancy: Prevalence and Determinants Among Pregnant Women Followed-Up at the Dschang District Hospital, West Region of Cameroon

Dabou S, Ongbayokolak NS, Fonkeng Sama L, Matene Foking E, Kamdom NM, Telefo PB

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:743-753

Published Date: 5 March 2022

Awareness of Genetic Polymorphism in Drug Metabolizing Enzymes and Transporters May Promote Personalized Type 2 Diabetes Management [Response to Letter]

Williams DM, Stephens JW

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:741-742

Published Date: 7 March 2022

Effects of Ultra-Long-Acting Insulin Compared to Long-Acting Insulin on Diabetic Ketoacidosis Incidence in Type 1 Diabetes Mellitus Patients

Alsofiani WA, Alessa BH, Alsabaan F, Althemery AU, Ghith AM, Alfaifi AA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:733-739

Published Date: 5 March 2022

The Impact of Health Policy on Patients’ Awareness of the Risks Associated with Obesity: An International Multicenter Study in Poland and Germany

Paczkowska A, Hoffmann K, Raakow J, Pross M, Berghaus R, Michalak M, Bryl W, Marzec K, Kopciuch D, Zaprutko T, Ratajczak P, Nowakowska E, Kus K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:723-732

Published Date: 3 March 2022

The Prevalence of Diabetes, Prediabetes and Associated Risk Factors in Hangzhou, Zhejiang Province: A Community-Based Cross-Sectional Study

Shi M, Zhang X, Wang H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:713-721

Published Date: 3 March 2022

Molecular Functions of Ceruloplasmin in Metabolic Disease Pathology

Liu Z, Wang M, Zhang C, Zhou S, Ji G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:695-711

Published Date: 3 March 2022

Effect of Anagliptin versus Sitagliptin on Renal Function: Subanalyzes from the REASON Trial

Teragawa H, Morimoto T, Fujii Y, Ueda T, Sakuma M, Shimabukuro M, Arasaki O, Node K, Nomiyama T, Ueda S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:685-694

Published Date: 3 March 2022

MAFLD is Associated with the Risk of Liver Fibrosis and Inflammatory Activity in HBeAg-Negative CHB Patients

Chen X, Zhou J, Wu L, Zhu X, Deng H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:673-683

Published Date: 1 March 2022

Comparison of Antiobesity Effects of Adipose-Derived Stromal/Stem Cells from Different Sources in a Natural Aging Model [Corrigendum]

Zhu Y, Wang T, He S, Pu S, Zhao H, Zhou Z, Wu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:671-672

Published Date: 1 March 2022

Adherence to Diabetes Self-Management and Its Associated Factors Among Adolescents Living with Type 1 Diabetes at Public Hospitals in Addis Ababa, Ethiopia: A Cross-Sectional Study

Geneti Y, Wondwossen K, Adimasu M, Deressa D, Aga F, Lami M, Abdisa L, Abebe S, Dinku H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:659-670

Published Date: 1 March 2022

Prevalence of Vitamin D Deficiency Between Type 2 Diabetes Mellitus Patients and Non-Diabetics in the Arab Gulf

Nasr MH, Hassan BAR, Othman N, Karuppannan M, Abdulaziz N, Mohammed AH, Alsarani MA, Eskembaji MH, Aman AM, Othman G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:647-657

Published Date: 28 February 2022

Statin Prescription Patterns and Associated Factors Among Patients with Type 2 Diabetes Mellitus Attending Diabetic Clinic at Muhimbili National Hospital, Dar es Salaam, Tanzania

Bideberi AT, Mutagaywa R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:633-646

Published Date: 27 February 2022

TRC150094, a Novel Mitochondrial Modulator, Reduces Cardio-Metabolic Risk as an Add-On Treatment: a Phase-2, 24-Week, Multi-Center, Randomized, Double-Blind, Clinical Trial

Joshi D, GJ P, Ghosh S, Mohanan A, Joshi S, Mohan V, Chowdhury S, Dutt C, Tandon N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:615-631

Published Date: 25 February 2022

Original Research

Central Obesity and Associated Factors Among Urban Adults in Dire Dawa Administrative City, Eastern Ethiopia

Israel E, Hassen K, Markos M, Wolde K, Hawulte B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:601-614

Published Date: 25 February 2022

Association of Nondiabetic Glucometabolic Status and Aortic Stiffness in Community Hypertension Patients

Zhou D, Yan M, Tang S, Feng Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:591-600

Published Date: 25 February 2022

The Prevalence of Coagulopathy and Associated Factors Among Adult Type II Diabetes Mellitus Patients Attending the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia

Getu F, Aynalem M, Bizuneh S, Enawgaw B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:579-590

Published Date: 24 February 2022

Identification and Validation of Hub Genes in Acute Pancreatitis and Hypertriglyceridemia

Zhang S, Liang Z, Xiang X, Liu L, Yang H, Tang G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:559-577

Published Date: 24 February 2022

Awareness of Genetic Polymorphism in Drug Metabolizing Enzymes and Transporters May Promote Personalized Type 2 Diabetes Management [Letter]

Zhu LL, Zhou Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:557-558

Published Date: 23 February 2022

Liver Enzymes are Associated with Hyperglycemia in Diabetes: A Three-Year Retrospective Study

Wan JY, Yang LZ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:545-555

Published Date: 23 February 2022

The Association of the Prevalence of Depression in Type 2 Diabetes Mellitus with Visual-Related Quality of Life and Social Support

Ding X, Rong S, Wang Y, Li D, Wen L, Zou B, Zang D, Feng K, Liang Y, Wang F, Zhai G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:535-544

Published Date: 22 February 2022

Association Between Serum Albumin Levels and Diabetic Peripheral Neuropathy Among Patients with Type 2 Diabetes: Effect Modification of Body Mass Index

Hu Y, Wang J, Zeng S, Chen M, Zou G, Li Y, Zhu L, Xu J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:527-534

Published Date: 22 February 2022

The Relationship Between Triglyceride Glucose Index and Vitamin D in Type 2 Diabetes Mellitus

Jia Y, Song T, Li Z, Zhou L, Chen S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:511-525

Published Date: 19 February 2022

High L-Valine Concentrations Associate with Increased Oxidative Stress and Newly-Diagnosed Type 2 Diabetes Mellitus: A Cross-Sectional Study

Hu W, Yang P, Fu Z, Wang Y, Zhou Y, Ye Z, Gong Y, Huang A, Sun L, Zhao Y, Yang T, Li Z, Jiang XC, Yu W, Zhou H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:499-509

Published Date: 19 February 2022

Adherence to Low-Carbohydrate Diets in Patients with Diabetes: A Narrative Review

Kumar NK, Merrill JD, Carlson S, German J, Yancy WS Jr

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:477-498

Published Date: 18 February 2022

Free Triiodothyronine and Free Triiodothyronine to Free Thyroxine Ratio Predict All-Cause Mortality in Patients with Diabetic Foot Ulcers

Hong J, Liu WY, Hu X, Chen WW, Jiang FF, Xu ZR, Shen FX, Zhu H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:467-476

Published Date: 18 February 2022

Risk Factors Analysis and Management of Cardiometabolic-Based Chronic Disease in Low- and Middle-Income Countries

Dutt C, Nunes Salles JE, Joshi S, Nair T, Chowdhury S, Mithal A, Mohan V, Kasliwal R, Sharma S, Tijssen J, Tandon N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:451-465

Published Date: 16 February 2022

Association Between Triglyceride-Glucose Index and 2-Year Adverse Cardiovascular and Cerebrovascular Events in Patients with Type 2 Diabetes Mellitus Who Underwent Off-Pump Coronary Artery Bypass Grafting

Chen L, Ding XH, Fan KJ, Gao MX, Yu WY, Liu HL, Yu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:439-450

Published Date: 16 February 2022

Dietary Advanced Glycation End Products Shift the Gut Microbiota Composition and Induce Insulin Resistance in Mice

Wang J, Cai W, Yu J, Liu H, He S, Zhu L, Xu J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:427-437

Published Date: 15 February 2022

Angiotensinogen and Risk of Stroke Events in Patients with Type 2 Diabetes Mellitus

Liu T, Liu W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:419-425

Published Date: 11 February 2022

Relations of Well-Being, Coping Styles, Perception of Self-Influence on the Diabetes Course and Sociodemographic Characteristics with HbA1c and BMI Among People with Advanced Type 2 Diabetes Mellitus

Łukasiewicz A, Kiejna A, Cichoń E, Jodko-Modlińska A, Obrębski M, Kokoszka A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:407-418

Published Date: 11 February 2022

Optical Coherence Tomography Angiography Biomarkers Predict Anatomical Response to Bevacizumab in Diabetic Macular Edema

Elnahry AG, Noureldine AM, Abdel-Kader AA, Sorour OA, Ramsey DJ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:395-405

Published Date: 9 February 2022

Associations Between GGT/HDL and MAFLD: A Cross-Sectional Study

Xing Y, Chen J, Liu J, Ma H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:383-394

Published Date: 9 February 2022

Original Research

The Anti-Obesity Potential of Cyperus rotundus Extract Containing Piceatannol, Scirpusin A and Scirpusin B from Rhizomes: Preclinical and Clinical Evaluations

Majeed M, Nagabhushanam K, Bhat B, Ansari M, Pandey A, Bani S, Mundkur L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:369-382

Published Date: 9 February 2022

The Association Between Fecal Short-Chain Fatty Acids, Gut Microbiota, and Visceral Fat in Monozygotic Twin Pairs

Yin XQ, An YX, Yu CG, Ke J, Zhao D, Yu K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:359-368

Published Date: 5 February 2022

Decreased Levels of miR-126 and miR-132 in Plasma and Vitreous Humor of Non-Proliferative Diabetic Retinopathy Among Subjects with Type-2 Diabetes Mellitus

Pramanik S, Saha C, Chowdhury S, Bose C, Bhattacharyya NP, Mondal LK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:345-358

Published Date: 4 February 2022

Serum Levels of Free Fatty Acids in Obese Mice and Their Associations with Routine Lipid Profiles

Sun SY, Yang WY, Tan Z, Zhang XY, Shen YL, Guo QW, Su GM, Chen X, Lin J, Fang DZ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:331-343

Published Date: 3 February 2022

MicroRNAs and Exosomal microRNAs May Be Possible Targets to Investigate in Gestational Diabetes Mellitus

Yang X, Wu N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:321-330

Published Date: 3 February 2022

Association of ADIPOQ Single-Nucleotide Polymorphisms with the Two Clinical Phenotypes Type 2 Diabetes Mellitus and Metabolic Syndrome in a Kinh Vietnamese Population

Truong S, Tran NQ, Ma PT, Hoang CK, Le BH, Dinh T, Tran L, Tran TV, Gia Le LH, Vu HA, Mai TP, Do MD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:307-319

Published Date: 3 February 2022

The Effects of Antral Preservation and Antral Resection on Body Composition, Glycemic Control and Bone Mineral Density Following Vertical Sleeve Gastrectomy in C57BL/6J Mice with Obesity and Type 2 Diabetes

Qi X, Li X, Jiao Y, Chen S, Song P, Qian Z, Tang L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:297-305

Published Date: 3 February 2022

Personalized Type 2 Diabetes Management: An Update on Recent Advances and Recommendations

Williams DM, Jones H, Stephens JW

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:281-295

Published Date: 4 February 2022

The Association Between Vitamin D and Type 2 Diabetes Mellitus Complicated with Non-Alcoholic Fatty Liver Disease: An Observational Cross-Sectional Study

Xing Y, Cheng T, Zhou F, Ma H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:269-280

Published Date: 2 February 2022

Relationship Between Serum Uric Acid-to-Creatinine Ratio and the Risk of Metabolic-Associated Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Xing Y, Chen J, Liu J, Song G, Ma H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:257-267

Published Date: 2 February 2022

Acylcarnitines: Can They Be Biomarkers of Diabetic Nephropathy?

Mu X, Yang M, Ling P, Wu A, Zhou H, Jiang J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:247-256

Published Date: 29 January 2022

Which Aspect of Patient–Provider Relationship Affects Acceptance and Adherence of Insulin Therapy in Type 2 Diabetes Mellitus? A Qualitative Study in Primary Care

Mathew BK, De Roza JG, Liu C, Goh LJ, Ooi CW, Chen E, Poon S, Tang WE

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:235-246

Published Date: 26 January 2022

Association of Circulating TXNIP Levels with Fatty Liver in Newly Diagnosed Type 2 Diabetes Mellitus

Guo Y, Chen J, Liu N, Liu Z, Shi B, Sun H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:225-233

Published Date: 25 January 2022

Moderate Treadmill Exercise Modulates Gut Microbiota and Improves Intestinal Barrier in High-Fat-Diet-Induced Obese Mice via the AMPK/CDX2 Signaling Pathway

Wang J, Zhang Q, Xia J, Sun H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:209-223

Published Date: 20 January 2022

Metabolic Dysfunction-Associated Fatty Liver Disease Increases the Risk of Gastroesophageal Reflux Symptoms

He Y, Duan ZJ, Wang CF, Wei YS, Cai MX

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:199-207

Published Date: 20 January 2022

The Single Nucleotide Polymorphisms (rs1292037 and rs13137) in miR-21 Were Associated with T2DM in a Chinese Population

Li Y, Yang J, Tao W, Yang M, Wang X, Lu T, Li C, Yang Y, Yao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:189-198

Published Date: 20 January 2022

Median Nerve Affection in Hypertensive Patients with and without Diabetes High-Resolution Ultrasound Assessment

Esmat A, Elshamy MI, Mohamed Zakaria D, Shady Z, Roshdy Mohamed E, El-Khouly N, Hassan MM, El-Senosy FM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:183-188

Published Date: 15 January 2022

The Relationship of Hyperferritinemia to Metabolism and Chronic Complications in Type 2 Diabetes

Shang X, Zhang R, Wang X, Yao J, Zhao X, Li H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:175-182

Published Date: 15 January 2022

The Association Between GC Gene Polymorphisms and Metabolic Syndrome in Chinese Rural Population: A Case–Control Study

Zhao T, Zhang D, Liu Y, Feng M, Xu Z, Huang H, Zhang L, Li W, Li X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:165-174

Published Date: 14 January 2022

Difference in Gastrointestinal Risk Associated with Use of GLP-1 Receptor Agonists: A Real-World Pharmacovigilance Study

Zhou Y, Chen M, Liu L, Chen Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:155-163

Published Date: 13 January 2022

Which BMI for Diabetes Patients is Better? From the View of the Adipose Tissue Macrophage-Derived Exosome

Liu X, Chu H, Ji Y, Bosnjak Z, Ao H, Li T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:141-153

Published Date: 13 January 2022

Astragaloside IV Ameliorates Streptozotocin Induced Pancreatic β-Cell Apoptosis and Dysfunction Through SIRT1/P53 and Akt/GSK3β/Nrf2 Signaling Pathways

Lin Y, Xu Y, Zheng X, Zhang J, Liu J, Wu G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:131-140

Published Date: 13 January 2022

Glycaemic Control in Youth and Young Adults: Challenges and Solutions

Khadilkar A, Oza C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:121-129

Published Date: 10 January 2022

Clinical Characteristics of Concomitant Diabetic Ketoacidosis in Type 2 Diabetes Patients with Acute Pancreatitis

Fu Y, Liu X, Cui B, Wang C, Liu Z, Zhao B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:111-119

Published Date: 11 January 2022

Custom-Molded Offloading Footwear Effectively Prevents Recurrence and Amputation, and Lowers Mortality Rates in High-Risk Diabetic Foot Patients: A Multicenter, Prospective Observational Study

Zhang X, Wang H, Du C, Fan X, Cui L, Chen H, Deng F, Tong Q, He M, Yang M, Tan X, Li L, Liang Z, Chen Y, Chen D, Armstrong DG, Deng W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:103-109

Published Date: 10 January 2022

RNF6 Targeted by miR-26a-5p Protects Pancreatic β-Cell Function Against Type 2 Diabetes

Yang F, Zhao S, Zhang X, Ding S, Xu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:93-102

Published Date: 11 January 2022

Kidney Function and Risk of Physical and Cognitive Impairment in Older Persons with Type 2 Diabetes at an Outpatient Clinic with Geriatric Assessment Implementation

Lin CF, Liu HC, Lin SY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:79-91

Published Date: 10 January 2022

The Association of Plasma Trimethylamine N-Oxide with Coronary Atherosclerotic Burden in Patients with Type 2 Diabetes Among a Chinese North Population

Yu N, Gu N, Wang Y, Zhou B, Lu D, Li J, Ma X, Zhang J, Guo X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:69-78

Published Date: 8 January 2022

The Correlation between Thyroid Hormone Levels and the Kidney Disease Progression Risk in Patients with Type 2 Diabetes

Yang Z, Duan P, Li W, Nie R, Lou X, Wang L, Wu K, Liu J, Tu P, Lai X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:59-67

Published Date: 5 January 2022

Mice Lacking Gpr75 are Hypophagic and Thin

Powell DR, Doree DD, DaCosta CM, Platt KA, Brommage R, Buhring L, Revelli JP, Shadoan MK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:45-58

Published Date: 5 January 2022

Diabetic Peripheral Neuropathy Associated with Cardiovascular Risk Factors and Glucagon-Like Peptide-1 Concentrations Among Newly Diagnosed Patients with Type 2 Diabetes Mellitus

Dinh Le T, Phi Thi Nguyen N, Thanh Thi Tran H, Luong Cong T, Ho Thi Nguyen L, Do Nhu B, Tien Nguyen S, Van Ngo M, Trung Dinh H, Thi Nguyen H, Trung Nguyen K, Duc-Cuong Le

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:35-44

Published Date: 6 January 2022

Efficacy of Digitally Supported and Real-Time Self-Monitoring of Blood Glucose-Driven Counseling in Patients with Type 2 Diabetes Mellitus: A Real-World, Retrospective Study in North India

Sabharwal M, Misra A, Ghosh A, Chopra G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:23-33

Published Date: 5 January 2022

Diagnostic Value of Neutrophil to Lymphocyte Ratio in Non-Alcoholic Fatty Liver Disease Evaluated Using Transient Elastography (TE) with Controlled Attenuated Parameter (CAP)

Lesmana CRA, Kencana Y, Rinaldi I, Kurniawan J, Hasan I, Sanityoso Sulaiman A, Gani RA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:15-22

Published Date: 5 January 2022

Platelet-to-Lymphocyte Ratio Predicts the Presence of Diabetic Neurogenic Bladder

Liu Y, Wang X, Wang L, Chen W, Liu W, Ye T, Hong J, Zhu H, Shen F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:7-13

Published Date: 4 January 2022

Personality Traits and Self-Care Behaviors in Adults with Type 2 Diabetes Mellitus

Mendoza-Catalán G, Rodríguez-Santamaría Y, Domínguez-Chávez CJ, Juárez-Medina LL, Villa-Rueda AA, González-Ramírez J, Gutiérrez-Valverde JM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2022, 15:1-6

Published Date: 4 January 2022

Evaluation of Red Blood Cell Parameters as a Biomarker for Long-Term Glycemic Control Monitoring Among Type 2 Diabetic Patients in Southwest Ethiopia: A Cross-Sectional Study

Asmamaw M, Sime T, Kene K, Fekadie Baye M, Teshome M, Zawdie B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4993-5000

Published Date: 30 December 2021

Affective Temperament and Glycemic Control – The Psychological Aspect of Obesity and Diabetes Mellitus

Lesiewska N, Kamińska A, Junik R, Michalewicz M, Myszkowski B, Borkowska A, Bieliński M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4981-4991

Published Date: 30 December 2021

Association Among Lipid Accumulation Product, Chinese Visceral Obesity Index and Diabetic Retinopathy in Patients with Type 2 Diabetes: A Cross-Sectional Study

Li X, Li HY, Yu ZW, Zhang YT, Tong XW, Gao XY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4971-4979

Published Date: 29 December 2021

Trajectory Analysis and Predictors of the Percentage of Body Fat Among Chinese Sleeve Gastrectomy Patients

Zhao K, Xu X, Zhu H, Ren Z, Zhang T, Yang N, Zhu S, Xu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4959-4970

Published Date: 29 December 2021

Prevalence of and Factors Associated with Diabetic Retinopathy in Patients with Diabetes Mellitus at Siriraj Hospital – Thailand’s Largest National Tertiary Referral Center

Boonsaen T, Choksakunwong S, Lertwattanarak R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4945-4957

Published Date: 29 December 2021

Role of Diabetes Mellitus in Acute Coronary Syndrome Patients with Heart Failure and Midrange Ejection Fraction Who Have Undergone Percutaneous Coronary Intervention: A 3-Year Case-Series Follow-Up Retrospective Study

Li L, Li G, Chen H, Feng Z, Zhang L, Chen L, Fan L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4931-4944

Published Date: 29 December 2021

Omental Adipose Removal Decreases High Blood Pressure in Hypertensive Patients Independent of Body Mass Index

Jiang L, Sun W, Zhang M, Wang Y, Tian Y, Li P, Lu Y, Xu T, Qiu M, Yang Y, Jia X, Kong X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4921-4930

Published Date: 29 December 2021

Risk Predictors of High Uric Acid Levels Among Patients with Type-2 Diabetes

Eljaaly Z, Mujammami M, Nawaz SS, Rafiullah M, Siddiqui K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4911-4920

Published Date: 24 December 2021

A Potential Participant in Type 2 Diabetes Bone Fragility: TIMP-1 at Sites of Osteocyte Lacunar-Canalicular System

Pei Q, Li J, Zhou P, Zhang J, Huang P, Fan J, Zou Z, Li X, Wang B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4903-4909

Published Date: 23 December 2021

Leptin Concentrations in Non-Obese and Obese Non-Diabetes Nigerian-Africans

Agbogu-Ike OU, Ogoina D, Onyemelukwe GC

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4889-4902

Published Date: 21 December 2021

IL-25 Treatment Improves Metabolic Syndrome in High-Fat Diet and Genetic Models of Obesity

Smith AD, Fan A, Qin B, Desai N, Zhao A, Shea-Donohue T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4875-4887

Published Date: 21 December 2021

Review

The Role of Glucagon in Glycemic Variability in Type 1 Diabetes: A Narrative Review

Guo K, Tian Q, Yang L, Zhou Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4865-4873

Published Date: 21 December 2021

Family History, Consanguinity and Other Risk Factors Affecting the Prevalence of Prediabetes and Undiagnosed Diabetes Mellitus in Overweight and Obese Yemeni Adults

Al-Sharafi BA, Qais AA, Salem K, Bashaaib MO

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4853-4863

Published Date: 20 December 2021

Regulation of Methylase METTL3 on Fat Deposition

Luo G, Chen J, Ren Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4843-4852

Published Date: 20 December 2021

Prevalence of Abdominal Obesity in Chinese Middle-Aged and Older Adults with a Normal Body Mass Index and Its Association with Type 2 Diabetes Mellitus: A Nationally Representative Cohort Study from 2011 to 2018

Chen X, Duan M, Hou R, Zheng M, Li H, Singh M, Li C, Liu K, Zhang F, Yang X, Luo Y, He Y, Wu L, Zheng D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4829-4841

Published Date: 20 December 2021

Frequency of Diabetic Ketoacidosis and Its Determinants Among Pediatric Diabetes Mellitus Patients in Northwest Ethiopia

Kidie AA, Lakew AM, Ayele T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4819-4827

Published Date: 19 December 2021

Association Between Dietary Salt and Plasma Glucose, Insulin and Hemoglobin A1c Levels Among Type 2 Diabetes Patients in Eastern China

Lin Y, Chattopadhyay K, Yang X, Li JL, Chen YS, Zhou Y, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4811-4818

Published Date: 19 December 2021

Diabetic Complications and Associated Factors: A 5-Year Facility-Based Retrospective Study at a Tertiary Hospital in Rwanda

Iradukunda A, Kembabazi S, Ssewante N, Kazibwe A, Kabakambira JD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4801-4810

Published Date: 18 December 2021

The Predictive Ability of Hepatic Steatosis Index for Gestational Diabetes Mellitus and Large for Gestational Age Infant Compared with Other Noninvasive Indices Among Chinese Pregnancies: A Preliminary Double-center Cohort Study

Song S, Duo Y, Zhang Y, Qiao X, Xu J, Zhang J, Peng Z, Chen Y, Nie X, Sun Q, Yang X, Wang A, Sun W, Fu Y, Dong Y, Lu Z, Yuan T, Zhao W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4791-4800

Published Date: 16 December 2021

Association Between Metabolic Syndrome and Peripheral Arterial Disease in Elderly Patients with Type 2 Diabetes

Gao L, Zhao W, Liu Q, Qin M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4783-4789

Published Date: 14 December 2021

Exosomes from β-Cells Promote Differentiation of Induced Pluripotent Stem Cells into Insulin-Producing Cells Through microRNA-Dependent Mechanisms

Guo Q, Lu Y, Huang Y, Guo Y, Zhu S, Zhang Q, Zhu D, Wang Z, Luo J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4767-4782

Published Date: 11 December 2021

Correlation Between Hemoglobin Glycosylation Index and Nerve Conduction Velocity in Patients with Type 2 Diabetes Mellitus

Li Z, Gao Y, Jia Y, Chen S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4757-4765

Published Date: 4 December 2021

Upregulated lncRNA HCG18 in Patients with Non-Alcoholic Fatty Liver Disease and Its Regulatory Effect on Insulin Resistance

Xia Y, Zhang Y, Wang H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4747-4756

Published Date: 3 December 2021

Remnant Cholesterol is an Independent Predictor of New-Onset Diabetes: A Single-Center Cohort Study

Xie G, Zhong Y, Yang S, Zou Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4735-4745

Published Date: 3 December 2021

Original Research

Prevalence and Associated Factors of Diabetic Retinopathy in a Russian Population. The Ural Eye and Medical Study

Bikbov MM, Gilmanshin TR, Zainullin RM, Kazakbaeva GM, Nuriyev IF, Zaynetdinov AF, Panda-Jonas S, Bikbova GM, Rakhimova EM, Rusakova IA, Khalimov TA, Safiullina KR, Fakhretdinova AA, Tuliakova AM, Gizzatov AV, Jonas JB

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4723-4734

Published Date: 3 December 2021

Relationship Between Fibroblast Growth Factor 19 and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus

Chung JO, Park SY, Cho DH, Chung DJ, Chung MY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4715-4721

Published Date: 3 December 2021

Association of Serum Amylase Activity and the Copy Number Variation of AMY1/2A/2B with Metabolic Syndrome in Chinese Adults

Zhan F, Chen J, Yan H, Wang S, Zhao M, Zhang S, Lan X, Maekawa M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4705-4714

Published Date: 2 December 2021

Urine Uric Acid Excretion Levels are Positively Associated with Obesity and Abdominal Obesity in Type 2 Diabetes Patients without Chronic Kidney Disease

Liu F, Chen S, Zhao W, Chen M, Ke J, Zhang Z, Lu J, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4691-4703

Published Date: 1 December 2021

Astragalus–Saffron–Rhubarb Mixture Delays the Progress of Diabetic Nephropathy in db/db Mice

Zhou XC, Liang YJ, Qin L, Wei GH, Wang JQ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4679-4690

Published Date: 1 December 2021

Analysis of Serum Metabolomics in Obese Mice Induced by High-Fat Diet

Bao L, Yang C, Shi Z, Wang Z, Jiang D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4671-4678

Published Date: 30 November 2021

Classic Type 1 Diabetes Mellitus and Fulminant Type 1 Diabetes Mellitus: Similarity and Discrepancy of Immunological Characteristics and Cytokine Profile

Ying L, Zhang Y, Yin J, Wang Y, Lu W, Zhu W, Bao Y, Zhou J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4661-4670

Published Date: 30 November 2021

Overexpression of circACTR2 in Gestational Diabetes Mellitus Predicts Intrauterine Death, Fetal Malformation, and Intrauterine Infection

Zhu C, Liu Y, Wu H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4655-4660

Published Date: 30 November 2021

Dysbiosis of the Salivary Microbiome is Associated with Hypertension and Correlated with Metabolic Syndrome Biomarkers

Sohail MU, Hedin L, Al-Asmakh M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4641-4653

Published Date: 25 November 2021

Mitophagy Disequilibrium, a Prominent Pathological Mechanism in Metabolic Heart Diseases

Li Y, Zheng N, Ding X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4631-4640

Published Date: 25 November 2021

Do Mindfulness Interventions Improve Obesity Rates in Children and Adolescents: A Review of the Evidence

Keck-Kester T, Huerta-Saenz L, Spotts R, Duda L, Raja-Khan N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4621-4629

Published Date: 25 November 2021

Review

Prediabetes in Adolescents: Prevalence, Management and Diabetes Prevention Strategies

Esquivel Zuniga R, DeBoer MD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4609-4619

Published Date: 25 November 2021

Effect of LncPVT1/miR-20a-5p on Lipid Metabolism and Insulin Resistance in NAFLD

Zhang H, Niu Q, Liang K, Li X, Jiang J, Bian C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4599-4608

Published Date: 23 November 2021

Gender Differences in the Association Between Obstructive Sleep Apnea and Diabetes

Tao Y, Li X, Yang G, Wang L, Lian J, Chang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4589-4597

Published Date: 23 November 2021

Children’s Lipid Accumulation Product Combining Visceral Adiposity Index is a Novel Indicator for Predicting Unhealthy Metabolic Phenotype Among Chinese Children and Adolescents

Dong Y, Bai L, Cai R, Zhou J, Ding W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4579-4587

Published Date: 23 November 2021

Associations of Dietary Salt and Its Sources with Hemoglobin A1c in Patients with Type 2 Diabetes Not Taking Anti-Diabetic Medications: Analysis Based on 6-Month Intervention with a Moderate Low-Carbohydrate Diet

Haimoto H, Murase T, Watanabe S, Maeda K, Wakai K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4569-4578

Published Date: 19 November 2021

Fibrinogen to Albumin Ratio as an Independent Risk Factor for Type 2 Diabetic Kidney Disease

Wang K, Xu W, Zha B, Shi J, Wu G, Ding H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4557-4567

Published Date: 15 November 2021

Plasma Lipocalin-2 and Adiponectin are Affected by Obesity Rather Than Type 2 Diabetes Mellitus per se

Al-Absi B, AL-Habori M, Saif-Ali R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4547-4556

Published Date: 16 November 2021

Comparison of Antiobesity Effects of Adipose-Derived Stromal/Stem Cells from Different Sources in a Natural Aging Model

Zhu Y, Wang T, He S, Pu S, Zhao H, Zhou Z, Wu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4535-4546

Published Date: 15 November 2021

RPS4Y1 Promotes High Glucose-Induced Endothelial Cell Apoptosis and Inflammation by Activation of the p38 MAPK Signaling

Chen Y, Chen Y, Tang C, Zhao Q, Xu T, Kang Q, Jiang B, Zhang L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4523-4534

Published Date: 12 November 2021

Combined Effects of Dyslipidemia and High Adiposity on the Estimated Glomerular Filtration Rate in a Middle-Aged Chinese Population

Wang X, Wang H, Li J, Gao X, Han Y, Teng W, Shan Z, Lai Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4513-4522

Published Date: 10 November 2021

The Prevalence and Control of Type 2 Diabetes Mellitus in Residents of a Rural Town, Shandong Province, China

Wei M, Dong L, Wang F, Cui K, Ma D, Yang N, Li Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4505-4512

Published Date: 11 November 2021

The Factors Influencing the Renal Glucose Threshold in Patients with Newly Diagnosed Type 2 Diabetes Mellitus

Cui SS, Duan LJ, Li JF, Qin YZ, Bao SQ, Jiang X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4497-4503

Published Date: 9 November 2021

Association Between Aspartate Aminotransferase to Alanine Aminotransferase Ratio and Incidence of Type 2 Diabetes Mellitus in the Japanese Population: A Secondary Analysis of a Retrospective Cohort Study

Chen L, Zhang K, Li X, Wu Y, Liu Q, Xu L, Li L, Hu H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4483-4495

Published Date: 9 November 2021

Newly-Diagnosed Diabetes and Sustained Hyperglycemia are Associated with Poorer Outcomes in COVID-19 Inpatients Without Pre-Existing Diabetes

Lin L, Chen Z, Ding T, Liu H, Zhou F, Huang X, Zhang X, Liu W, Zhang BH, Yuan Y, Zhang P, Zhang XJ, She ZG, Cai J, Chen W, Li H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4469-4482

Published Date: 9 November 2021

A Predictive Model of Metabolic Syndrome by Medical Examination: Evidence from an 8-Year Chinese Cohort

Guo H, Jiang W, Zhao B, Xiong Y, Lu Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4459-4467

Published Date: 8 November 2021

Acarbose Reduces Low-Grade Albuminuria Compared to Metformin in Chinese Patients with Newly Diagnosed Type 2 Diabetes

Song L, Kong X, Yang Z, Zhang J, Yang W, Zhang B, Chen X, Wang X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4451-4458

Published Date: 5 November 2021

Relationship Between Sclerostin (SOST) Expression and Genetic Loci rs851056, rs1230399 Polymorphisms and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes in Xinjiang

Li J, Ren Y, Li S, Li J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4443-4450

Published Date: 4 November 2021

PAID-PL—The Polish Version of the Problem Areas in Diabetes Scale: Perfect Reliability and a One-Factor Structure

Cichoń E, Kiejna A, Gondek TM, Obrębski M, Sutkowska E, Lloyd CE, Sartorius N, Kokoszka A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4433-4441

Published Date: 2 November 2021

Effect of Metformin on Breast Density in Overweight/Obese Premenopausal Women

Leng W, Pu D, Jiang J, Lei X, Wu Q, Chen B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4423-4432

Published Date: 3 November 2021

Prevalence and Factors Associated with Microalbuminuria in Pediatric Patients with Type 1 Diabetes Mellitus at a Large Tertiary-Level Hospital in Botswana

Ramaphane T, Gezmu AM, Tefera E, Gabaitiri L, Nchingane S, Matsheng-Samuel M, Joel D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4415-4422

Published Date: 2 November 2021

CircRNA circVEGFC is Highly Expressed in Gestational Diabetes Mellitus (GDM) and It is Correlated with Multiple Adverse Events

She W, Li T, Liu Y, Liu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4409-4414

Published Date: 1 November 2021

Original Research

To Assess Liraglutide’s Therapeutic Effect in Patients with Type 2 Diabetes Mellitus Using Flash Glucose Monitoring System

Yin J, Han M, Li L, Li Y, Liu Z, Yang J, Liu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4399-4407

Published Date: 29 October 2021

Association Between Early Markers of Renal Injury and Type 2 Diabetic Peripheral Neuropathy

Yang Z, Lou X, Zhang J, Nie R, Liu J, Tu P, Duan P

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4391-4397

Published Date: 30 October 2021

Incidence and Predictors of Chronic Kidney Disease among Diabetes Mellitus Patients: A Retrospective Follow-Up Study at a Tertiary Health-Care Setting of Ethiopia

Debele GR, Hajure M, Wolde HF, Yenit MK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4381-4390

Published Date: 28 October 2021

Obesity-Related Glomerulopathy: From Mechanism to Therapeutic Target

Wei L, Li Y, Yu Y, Xu M, Chen H, Li L, Peng T, Zhao K, Zhuang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4371-4380

Published Date: 28 October 2021

Cognitive Impairment and Related Factors Among Middle-Aged and Elderly Patients with Type 2 Diabetes from a Bio-Psycho-Social Perspective

Xu W, Hu X, Zhang X, Ling C, Wang C, Gao L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4361-4369

Published Date: 28 October 2021

Prdm16-Mediated Browning is Involved in Resistance to Diet-Induced and Monosodium Glutamate-Induced Obesity

Liang J, Jia Y, Yan H, Shen Q, Bian W, Zhao D, Xu Y, Jin Y, Yang M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4351-4360

Published Date: 27 October 2021

Barriers to Diabetes Patients’ Self-Care Practices in Eastern Ethiopia: A Qualitative Study from the Health Care Providers Perspective

Letta S, Aga F, Yadeta TA, Geda B, Dessie Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4335-4349

Published Date: 22 October 2021

Heamanetic Effects of a Dioxidovanadium(V) Complex in STZ-Induced Diabetic Male Sprague Dawley Rats

Xulu N, Ngubane P, Khathi A, Booysen I, Sibiya N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4321-4333

Published Date: 19 October 2021

The Magnitude, Types, and Roles of Social Support in Diabetes Management among Diabetics’ in Southern Ethiopia: a Multilevel, Multicenter Cross-Sectional Study

Jaafaripooyan E, Habebo TT, Mosadeghrad AM, Foroushani AR, Anshebo DG

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4307-4319

Published Date: 19 October 2021

Gender-Specific Independent and Combined Effects of the Progesterone and 17-Hydroxyprogesterone on Metabolic Syndrome: From the Henan Rural Cohort Study

Wang M, Nie L, Wei D, Liu P, Zhang L, Fan K, Song Y, Wang L, Xu Q, Wang J, Liu X, Li L, Mao Z, Wang C, Huo W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4297-4306

Published Date: 18 October 2021

The Profile and Function of Gut Microbiota in Diabetic Nephropathy

Chen W, Zhang M, Guo Y, Wang Z, Liu Q, Yan R, Wang Y, Wu Q, Yuan K, Sun W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4283-4296

Published Date: 19 October 2021

Analysis of Endocrine and Metabolic Indexes in Non-Obese Patients with Polycystic Ovary Syndrome and Its Compare with Obese Patients

Shi W, Zhao Q, Zhao X, Xing C, He B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4275-4281

Published Date: 15 October 2021

Enhanced Expression of miR-34c in Peripheral Plasma Associated with Diabetic Foot Ulcer in Type 2 Diabetes Patients

Wu T, Xie D, Zhao X, Xu M, Luo L, Deng D, Chen M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4263-4273

Published Date: 15 October 2021

Assessment of Cardiovascular Risk Factors and Their Interactions in the Risk of Coronary Heart Disease in Patients with Type 2 Diabetes with Different Weight Levels, 2013–2018

Wang C, Ye D, Xie Z, Huang X, Wang Z, Shangguan H, Zhu W, Wang S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4253-4262

Published Date: 14 October 2021

QSHY Granules Promote White Adipose Tissue Browning and Correct BCAAs Metabolic Disorder in NAFLD Mice

Zhang B, Ni M, Li X, Liu Q, Hu Y, Zhao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4241-4251

Published Date: 14 October 2021

LncRNA LINC00673 is Downregulated in Diabetic Retinopathy and Regulates the Apoptosis of Retinal Pigment Epithelial Cells via Negatively Regulating p53

Cheng Y, Zhu Y, Ma L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4233-4240

Published Date: 13 October 2021

Latent Autoimmune Diabetes in Adults (LADA) and its Metabolic Characteristics among Yemeni Type 2 Diabetes Mellitus Patients

Al-Zubairi T, AL-Habori M, Saif-Ali R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4223-4232

Published Date: 13 October 2021

ANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells

Xu F, Wang N, Li G, Tian D, Shi X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4209-4221

Published Date: 11 October 2021

Cross-Sectional Analysis of the Involvement of Interleukin-17A in Diabetic Retinopathy in Elderly Individuals with Type 2 Diabetes Mellitus

Liu F, Han F, Liu X, Yang L, Jiang C, Cui C, Yuan F, Zhang X, Gong L, Hou X, Liu Y, Chen L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4199-4207

Published Date: 9 October 2021

Trends in Serum Lipid Profiles Among Korean Adolescents, 2007–2018

Jeong DY, Kim SH, Seo MY, Kang SY, Park MJ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4189-4197

Published Date: 7 October 2021

Prevalence, Patient Predictors, and Referral Patterns for Diabetes-Related Complications Treated at a Central Hospital in KwaZulu Natal

Mtshali S, Mahomed O

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4181-4188

Published Date: 7 October 2021

Serum Human Epididymis Protein 4 is a Potential Biomarker for Early Chronic Kidney Disease in an Obese Population [Retraction]

Tan S, Zeng Y, Kuang S, Li J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4179-4180

Published Date: 6 October 2021

Ethyl 2-[2,3,4-Trimethoxy-6-(1-Octanoyl)Phenyl] Acetate (TMPA) Ameliorates Lipid Accumulation by Disturbing the Combination of LKB1 with Nur77 and Activating the AMPK Pathway in HepG2 Cells and Mice Primary Hepatocytes

Wang X, Li G, Guo C, Zhang J, Kong J, He J, Li F, Liu Y, Yang Y, Lu Z, Liu J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4165-4177

Published Date: 2 October 2021

Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism

Wang W, He J, Hu Y, Song Y, Zhang X, Guo H, Wang X, Keerman M, Ma J, Yan Y, Zhang J, Ma R, Guo S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4155-4163

Published Date: 1 October 2021

Application Progress of Nano Silver Dressing in the Treatment of Diabetic Foot

Lin H, BoLatai A, Wu N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4145-4154

Published Date: 1 October 2021

Serum Fibroblast Growth Factor 23 Level and Liver Fat Content in MAFLD: A Community-Based Cohort

Cao W, Xu Y, Shen Y, Wang Y, Ma X, Bao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4135-4143

Published Date: 29 September 2021

Original Research

Metabolic Syndrome Associated with Tobacco and Caffeine Products Use Among Refugee Adolescents: Risk of Dyslipidemia

Damiri B, Khatib O, Nazzal Z, Sanduka D, Igbaria S, Thabaleh A, Farhoud A, Saudi L, Belkebir S, Al Ali R, Alili M, Hamdan M, Safarini OA, Younis O

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4121-4133

Published Date: 29 September 2021

Variability in Annual Fasting Glucose and the Risk of Peripheral Artery Disease in Patients with Diabetes Mellitus

Chang YS, Lee LY, Lee IT

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4109-4119

Published Date: 24 September 2021

Gender Differences in the Relationship of Waist Circumference to Coronary Artery Lesions and One-Year Re-Admission Among Coronary Artery Disease Patients with Normal Body Mass Index

Luan H, Song Y, Cao L, Wang P, Zhu D, Tian G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4097-4107

Published Date: 23 September 2021

Use of Anthropometric Measures of Obesity to Predict Diabetic Retinopathy in Patients with Type 2 Diabetes in China

Yi QX, Zhu LN, Ma J, Yu XJ, Liu L, Shen J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4089-4095

Published Date: 22 September 2021

Immunogenetic Prediction of VDR Gene SNPs: Lack of Association with Susceptibility to Type 1 Diabetes in Jordanian Patients

Khdair SI, Jarrar YB, Jarrar W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4079-4087

Published Date: 21 September 2021

Epidemiology of Isolated Impaired Glucose Tolerance Among Adults Aged Above 50 Years in Rural China

Tian X, Li Y, Liu J, Lin Q, Yang Q, Tu J, Wang J, Li J, Ning X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4067-4078

Published Date: 16 September 2021

Secondary Hyperparathyroidism in Obese Patients Post Sleeve Gastrectomy

Altawil E, Alkofide H, Alamri H, Alhassan N, Alsubaie H, Alqahtani A, Alobaid O

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4059-4066

Published Date: 16 September 2021

Combination of Metformin and Exercise in Management of Metabolic Abnormalities Observed in Type 2 Diabetes Mellitus

Jevtovic F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4043-4057

Published Date: 16 September 2021

Using Metabolic and Biochemical Indicators to Predict Diabetic Retinopathy by Back-Propagation Artificial Neural Network

Su B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4031-4041

Published Date: 15 September 2021

The Effects of Diosgenin on Hypolipidemia and Its Underlying Mechanism: A Review

Sun F, Yang X, Ma C, Zhang S, Yu L, Lu H, Yin G, Liang P, Feng Y, Zhang F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4015-4030

Published Date: 15 September 2021

Identifying Needs and Barriers to Diabetes Dietary Education in Chinese People with Type 2 Diabetes and Their Family Members in Guangzhou: A Qualitative Study

Hu X, Zhang Y, Yao B, Lin B, Yang D, Ling C, Gao L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:4005-4014

Published Date: 15 September 2021

Association of Metabolic Syndrome with Aerobic Exercise and LPL rs3779788 Polymorphism in Taiwan Biobank Individuals

Hsu CS, Chang ST, Nfor ON, Lee KJ, Ho CC, Liu CC, Lee SS, Liaw YP

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3997-4004

Published Date: 14 September 2021

LncRNA SOX2OT is Upregulated in Gestational Diabetes Mellitus (GDM) and Correlated with Multiple Adverse Events

Ran G, Zhu X, Qin Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3989-3995

Published Date: 10 September 2021

FOXA1 Suppresses SATB1 Transcription and Inactivates the Wnt/β-Catenin Pathway to Alleviate Diabetic Nephropathy in a Mouse Model

Zhu H, Peng J, Li W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3975-3987

Published Date: 10 September 2021

Association Between Blood Pressure and Branched-Chain/Aromatic Amino Acid Excretion Rate in 24-Hour Urine Samples from Elderly Hypertension Patients

Wang F, Wang B, Chen X, Liu W, Wang G, Li X, Liu X, Li N, Zhang J, Yin T, Jing J, Chang X, Jin Y, Zhang Y, Zhao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3965-3973

Published Date: 10 September 2021

Diabetes During the Fasting Month of Ramadan: Is Telemedicine as Efficient as Conventional Follow-Up? Results from a Moroccan Comparative Study

Motaib I, Elamari S, Khalis M, Drissi Oudghiri M, Laidi S, Chadli A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3959-3964

Published Date: 8 September 2021

Impact of Hyperinsulinemia on Long-Term Clinical Outcomes of Percutaneous Coronary Intervention in Patients without Diabetes Who Have Acute Myocardial Syndrome

Tan Q, Chen M, Hao J, Wei K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3949-3957

Published Date: 7 September 2021

Metformin and Malignant Tumors: Not Over the Hill [Response to Letter]

Leng W, Jiang J, Chen B, Wu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3947-3948

Published Date: 8 September 2021

Understanding Competitive Endogenous RNA Network Mechanism in Type 1 Diabetes Mellitus Using Computational and Bioinformatics Approaches

Yi X, Cheng X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3865-3945

Published Date: 8 September 2021

Changes of Necroptosis in Irbesartan Medicated Cardioprotection in Diabetic Rats

Xu Q, Tan X, Xian W, Geng J, Li H, Tang B, Zhang H, Wang H, Gao Q, Kang P

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3851-3863

Published Date: 7 September 2021

Effect of Angiotensin Receptor Blocker and Angiotensin Converting Enzyme Inhibitor on Kidney Function and Blood Potassium Level in Indonesian Type 2 Diabetes Mellitus with Hypertension: A Three-Month Cohort Study

Puspita FM, Yunir E, Agustina PS, Sauriasari R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3841-3849

Published Date: 7 September 2021

Metformin and Malignant Tumors: Not Over the Hill: A Short Comment [Letter]

Rastmanesh R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3839-3840

Published Date: 7 September 2021

The Association of Aspartate Aminotransferase/Alanine Aminotransferase Ratio with Diabetic Nephropathy in Patients with Type 2 Diabetes

Xu J, Shi X, Pan Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3831-3837

Published Date: 7 September 2021

Association Between Knowledge of Hypoglycemia and Likelihood of Experiencing Hypoglycemia Among Patients with Insulin-Treated Diabetes Mellitus

Almigbal TH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3821-3829

Published Date: 4 September 2021

Oral Processing, Satiation and Obesity: Overview and Hypotheses: A Short Comment [Letter]

Rastmanesh R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3819-3820

Published Date: 2 September 2021

Is Office Blood Pressure Measurement Reliable in Obese Adolescents?

Tepe D, Yılmaz S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3809-3817

Published Date: 1 September 2021

Explore the Effect and Target of Liraglutide on Islet Function in Type 2 Diabetic Rats by miRNA Omics Technology

Guo Q, Xu Y, Li J, An W, Luo D, Huang C, Huang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3795-3807

Published Date: 1 September 2021

Alterations of Ocular Surface Parameters in Type 2 Diabetic Patients

Liang S, Niu W, Wang H, Yang L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3787-3793

Published Date: 28 August 2021

Original Research

High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes

Powell DR, Revelli JP, Doree DD, DaCosta CM, Desai U, Shadoan MK, Rodriguez L, Mullens M, Yang QM, Ding ZM, Kirkpatrick LL, Vogel P, Zambrowicz B, Sands AT, Platt KA, Hansen GM, Brommage R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3753-3785

Published Date: 28 August 2021

Association Between Chinese Visceral Adiposity Index and Incident Type 2 Diabetes Mellitus in Japanese Adults

Shang L, Li R, Zhao Y, Sun H, Tang B, Hou Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3743-3751

Published Date: 24 August 2021

Relationship Between Skeletal Muscle Mass to Visceral Fat Area Ratio and Cardiovascular Risk in Type 2 Diabetes

Liu D, Zhong J, Wen W, Ruan Y, Zhang Z, Sun J, Chen H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3733-3742

Published Date: 25 August 2021

Aberrantly Expressed Non-Coding RNAs in the Placenta and Their Role in the Pathophysiology of Gestational Diabetes Mellitus

Du R, Wu N, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3719-3732

Published Date: 21 August 2021

Investigation of the Reference Interval Values of Fasting Plasma Glucose, Blood Pressure, and Blood Lipids in the Longevity People Aged 90 Years Old and Above

Wang Z, Ni X, Gao D, Sun L, Zhu X, Jiao J, Zhou Q, Chen C, Zhang N, Wu Z, Yang Z, Yuan H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3711-3718

Published Date: 21 August 2021

Association Between Serum Human Epididymis Protein 4 Levels and Cardiovascular Events in Obese Patients with Breast Cancer

Wang L, Hu N, Jiang Z, Luo P, Yi N, Chen Y, Zhou N, Liu L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3703-3710

Published Date: 21 August 2021

Inverse Association Between Iodine Status and Prevalence of Metabolic Syndrome: A Cross-Sectional Population-Based Study in a Chinese Moderate Iodine Intake Area

Zhao J, Su Y, Zhang JA, Fang M, Liu X, Jia X, Li X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3691-3701

Published Date: 20 August 2021

Review

Metformin and Malignant Tumors: Not Over the Hill

Leng W, Jiang J, Chen B, Wu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3673-3689

Published Date: 17 August 2021

Older Underweight Pregnant Women Beat Young Overweight/Obese Ones on Incidence of Gestational Diabetes

Li F, Zhou X, Cheng D, Wang H, Xu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3667-3672

Published Date: 13 August 2021

White Matter Hyperintensities of Bilateral Lenticular Putamen in Patients with Proliferative Diabetic Retinopathy: A Voxel‐based Morphometric Study

Xiao A, Ge QM, Zhong HF, Zhang LJ, Shu HY, Liang RB, Shao Y, Zhou Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3653-3665

Published Date: 12 August 2021

Assessment of Microcirculation in the Type 2 Diabetic and Impaired Glucose Tolerance Feet of Elderly Men by CEUS

Li X, Wu L, Yang Z, Hu Y, Zhou C, Ji R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3647-3652

Published Date: 11 August 2021

Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease

Machado MV

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3627-3645

Published Date: 11 August 2021

Low Vibrational Training as an Additional Intervention for Postural Balance, Balance Confidence and Functional Mobility in Type 2 Diabetic Patients with Lower Limb Burn Injury: A Randomized Clinical Trial

Ibrahim ZM, Ali OI, Moawd SA, Eid M, Taha MM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3617-3626

Published Date: 11 August 2021

Is Physical Exercise in Hypoxia an Interesting Strategy to Prevent the Development of Type 2 Diabetes? A Narrative Review

De Groote E, Deldicque L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3603-3616

Published Date: 11 August 2021

Review

A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives

Reed J, Bain S, Kanamarlapudi V

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3567-3602

Published Date: 10 August 2021

Plasma Nesfatin-1: Potential Predictor and Diagnostic Biomarker for Cognitive Dysfunction in T2DM Patient

Xu D, Yu Y, Xu Y, Ge J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3555-3566

Published Date: 10 August 2021

Nomogram Model for Screening the Risk of Type II Diabetes in Western Xinjiang, China

Wang Y, Zhang Y, Wang K, Su Y, Zhuge J, Li W, Wang S, Yao H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3541-3553

Published Date: 7 August 2021

The Impact of the One-Day Clinic Diabetes Mellitus Management Model on Perinatal Outcomes in Patients with Gestational Diabetes Mellitus

Cao YM, Wang W, Cai NN, Ma M, Liu J, Zhang P, Xue L, Liu YY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3533-3540

Published Date: 6 August 2021

The Combined Use of a Non-Invasive Skin-Stretching Device and the Negative-Pressure Wound Therapy Technique in the Treatment of Postoperative Diabetic Foot

Wang L, Wang C, Chen H, Chen Y, Li J, Xiao L, Zhu D, Yang C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3523-3532

Published Date: 5 August 2021

When Inappropriate Use of Insulin is Dangerous: The Utility of C-Peptide Assay in the Era of Cardioprotective Antidiabetic Drugs

Volpe S, Tortorella C, Solfrizzi V, Piazzolla G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3517-3521

Published Date: 5 August 2021

Effects of Short-Term Dietary Fiber Intervention on Gut Microbiota in Young Healthy People

Tian T, Zhang X, Luo T, Wang D, Sun Y, Dai J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3507-3516

Published Date: 5 August 2021

Dissolution Profile Evaluation of Eight Brands of Metformin Hydrochloride Tablets Available in Jimma, Southwest Ethiopia

Umeta B, Bekele A, Mohammed T, Duguma M, Teshome H, Mekonnen Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3499-3506

Published Date: 5 August 2021

Effect of Metabolic Health and Obesity Phenotype on Risk of Diabetes Mellitus: A Population-Based Longitudinal Study

Zhu X, Hu J, Guo H, Ji D, Yuan D, Li M, Yan T, Xue C, Ma H, Zhou X, Liu Y, Li Y, Sun K, Liu Y, Sun Z, Wang B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3485-3498

Published Date: 5 August 2021

SERPINH1, Targeted by miR-29b, Modulated Proliferation and Migration of Human Retinal Endothelial Cells Under High Glucose Conditions

Hu L, Liu Y, Wei C, Jin H, Mei L, Wu C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3471-3483

Published Date: 4 August 2021

Osteoclasts May Affect Glucose Uptake-Related Insulin Resistance by Secreting Resistin

Li X, Sun F, Lu J, Zhang J, Wang J, Zhu H, Gu M, Ma J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3461-3470

Published Date: 31 July 2021

Associations of Serum Uric Acid with Clustering of Cardiovascular Risk Factors and a 10-Year Atherosclerotic Cardiovascular Disease Risk Score in Jiangsu Adults, China

Tian T, Wang Y, Xie W, Zhang J, Zhu Q, Peng X, Zhou Y, Dai Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3447-3460

Published Date: 28 July 2021

Estimation of the Prevalence of Nonalcoholic Fatty Liver Disease in an Adult Population in Northern China Using the Data Mining Approach

Yang T, Zhao B, Pei D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3437-3445

Published Date: 28 July 2021

Characteristics of Body Composition and Lifestyle in Chinese University Students with Normal-Weight Obesity: A Cross-Sectional Study

Maitiniyazi G, Chen Y, Qiu YY, Xie ZX, He JY, Xia SF

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3427-3436

Published Date: 28 July 2021

MAFLD Criteria May Overlook a Subtype of Patient with Steatohepatitis and Significant Fibrosis

Huang J, Xue W, Wang M, Wu Y, Singh M, Zhu Y, Kumar R, Lin S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3417-3425

Published Date: 27 July 2021

Oral Processing, Satiation and Obesity: Overview and Hypotheses

Slyper A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3399-3415

Published Date: 26 July 2021

Inflammatory Biomarkers Levels in T2DM Emirati Patients with Diabetic Neuropathy

Mussa BM, Srivastava A, Al-Habshi A, Mohammed AK, Halwani R, Abusnana S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3389-3397

Published Date: 26 July 2021

Differences of Angiogenesis Factors in Tumor and Diabetes Mellitus

Tan S, Zang G, Wang Y, Sun Z, Li Y, Lu C, Wang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3375-3388

Published Date: 24 July 2021

Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study

Ngo Nkondjock VR, Cheteu Wabo TM, Kosgey JC, Zhang Y, Amporfro DA, Adnan H, Shah I, Li Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3361-3373

Published Date: 24 July 2021

Metformin-Insulin versus Metformin-Sulfonylurea Combination Therapies in Type 2 Diabetes: A Comparative Study of Glycemic Control and Risk of Cardiovascular Diseases in Addis Ababa, Ethiopia

Gebrie D, Manyazewal T, Ejigu DA, Makonnen E

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3345-3359

Published Date: 24 July 2021

Blood Glucose and Renal Function Evaluation in Patients with Viral Hepatitis

Hsu WT, Yang DH, Liao CC, Chen JW, Hsu WH, Kuo CW, Hsu HC, Chang SH, Chen LM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3337-3344

Published Date: 20 July 2021

High Prevalence of Obesity but Low Physical Activity in Children Aged 9–11 Years in Beijing

Liu M, Cao B, Liu M, Liang X, Wu D, Li W, Su C, Chen J, Gong C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3323-3335

Published Date: 20 July 2021

Effect of Leptin on Chronic Inflammatory Disorders: Insights to Therapeutic Target to Prevent Further Cardiovascular Complication

Dessie G, Ayelign B, Akalu Y, Shibabaw T, Molla MD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3307-3322

Published Date: 17 July 2021

Relationship Between the TyG Index and Diabetic Kidney Disease in Patients with Type-2 Diabetes Mellitus

Lv L, Zhou Y, Chen X, Gong L, Wu J, Luo W, Shen Y, Han S, Hu J, Wang Y, Li Q, Wang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3299-3306

Published Date: 17 July 2021

Possible Regulation of bFGF Expression by Mast Cells in Osteoarthritis Patients with Obesity: A Cross-Sectional Study

Takata K, Uchida K, Takano S, Mukai M, Inoue G, Sekiguchi H, Aikawa J, Miyagi M, Iwase D, Takaso M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3291-3297

Published Date: 16 July 2021

Advances in Biological Functions and Clinical Studies of FGF21

Lin W, Zhang T, Zhou Y, Zheng J, Lin Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3281-3290

Published Date: 16 July 2021

Poor Glycemic Control and Its Contributing Factors Among Type 2 Diabetes Patients at Adama Hospital Medical College in East Ethiopia

Yosef T, Nureye D, Tekalign E

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3273-3280

Published Date: 15 July 2021

Sex -Specific Differences in the Association Between Metabolic Syndrome and Carotid Intima-Media Thickness Among a Low-Income Population in China: A Cross-Sectional Study

Fan L, Yang Q, Zhang X, Lin Q, Guo D, Liu J, Tu J, Wang J, Li Y, Ning X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3263-3272

Published Date: 15 July 2021

Prevalence and Impact of Metabolic Syndrome on Short-Term Prognosis in Patients with Acute Coronary Syndrome: Prospective Cohort Study

Fanta K, Daba FB, Asefa ET, Chelkeba L, Melaku T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3253-3262

Published Date: 15 July 2021

A Comparison Between the Therapeutic Effect of Metformin Alone versus a Combination Therapy with Insulin in Uncontrolled, Non-Adherence Patients with Type 2 Diabetes: Six Months Follow-Up

Paczkowska A, Hoffmann K, Michalak M, Bryl W, Kopciuch D, Zaprutko T, Ratajczak P, Nowakowska E, Kus K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3243-3252

Published Date: 14 July 2021

Qihu Preparation Ameliorates Diabetes by Activating the AMPK Signaling Pathway in db/db Mice

Zeng H, Li X, Zhou D, Wang N, Yu X, Long L, Cheng H, Zhou S, Shen Z, Zhou W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3229-3241

Published Date: 14 July 2021

Serum Heparanase: A New Clinical Biomarker Involved in Senile Metabolic Inflammatory Syndrome

Wang Q, Zhou X, Mei G, Wang J, Yu Z, Hu Y, Guo X, Zhang H, Xu X, He C, Guo J, Tao Y, Zhou H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3221-3228

Published Date: 13 July 2021

Altered Functional Connectivity Strength of Primary Visual Cortex in Subjects with Diabetic Retinopathy

Qi CX, Huang X, Tong Y, Shen Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3209-3219

Published Date: 13 July 2021

Cardiovascular Safety and Superiority of Anti-Obesity Medications

Alobaida M, Alrumayh A, Oguntade AS, Al-Amodi F, Bwalya M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3199-3208

Published Date: 13 July 2021

Original Research

Ideal Cardiovascular Health and Vascular Phenotype Associations in Mothers with Obesity and Their Six-Year-Old Children

Litwin L, Sundholm JKM, Meinilä J, Kulmala J, Tammelin TH, Rönö K, Koivusalo SB, Eriksson JG, Sarkola T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3187-3197

Published Date: 13 July 2021

Effects of Oil Tea on Obesity and Dyslipidemia: A Cross-Sectional Study in China

Cai J, Liu S, Li Y, Liu Q, Xu M, Mo C, Mai T, Xu X, Tang X, Chen Q, Nong C, Lu H, He H, Tang J, Zhang J, Wei C, Tan D, Qin J, Zhang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3173-3185

Published Date: 12 July 2021

Biochanin A Regulates Cholesterol Metabolism Further Delays the Progression of Nonalcoholic Fatty Liver Disease

Fan Y, Yan LT, Yao Z, Xiong GY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3161-3172

Published Date: 9 July 2021

A Meal Replacement Program for the Treatment of Obesity: A Cost-Effectiveness Analysis from the Swiss Payer’s Perspective

Nuijten M, Dainelli L, Rasouli B, Araujo Torres K, Perugini M, Marczewska A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3147-3160

Published Date: 8 July 2021

Review

Assessment and Management of Diabetic Patients During the COVID-19 Pandemic

Verma AK, Beg MMA, Bhatt D, Dev K, Alsahli MA, Rahmani AH, Goyal Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3131-3146

Published Date: 8 July 2021

Poor Glycemic Control and the Contributing Factors Among Type 2 Diabetes Mellitus Patients Attending Outpatient Diabetes Clinic at Mbarara Regional Referral Hospital, Uganda

Patrick NB, Yadesa TM, Muhindo R, Lutoti S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3123-3130

Published Date: 8 July 2021

Contribution of Different Phenotypes of Obesity to Metabolic Abnormalities from a Cross-Sectional Study in the Northwest China

Lu X, Wang Q, Liang H, Xu L, Sha L, Wu Y, Ma L, Yang P, Lei H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3111-3121

Published Date: 7 July 2021

Pre-Existing Diabetes Limits Survival Rate After Immune Checkpoint Inhibitor Treatment for Advanced Lung Cancer: A Retrospective Study in Japan [Corrigendum]

Hisanaga K, Uchino H, Kakisu N, Miyagi M, Yoshikawa F, Sato G, Isobe K, Kishi K, Homma S, Hirose T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3109-3110

Published Date: 6 July 2021

Connecting Peripheral to Central Neuropathy: Examination of Nerve Conduction Combined with Olfactory Tests in Patients with Type 2 Diabetes

Ni W, Zhang Z, Zhang B, Zhang W, Cheng H, Miao Y, Chen W, Liu J, Zhu D, Bi Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3097-3107

Published Date: 6 July 2021

Liver Stiffness Measurement by Using Transient Elastography in Bangladeshi Patients with Type 2 Diabetes Mellitus and Ultrasonography-Diagnosed Nonalcoholic Fatty Liver Disease

Alam MS, Kamrul-Hasan ABM, Kalam ST, Rahman SMM, Hoque MI, Islam MB, Paul AK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3089-3096

Published Date: 6 July 2021

Complement C7 is Specifically Expressed in Mesangial Cells and is a Potential Diagnostic Biomarker for Diabetic Nephropathy and is Regulated by miR-494-3p and miR-574-5p

Guo H, Yan Z, Hu Y, Huang X, Pan C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3077-3088

Published Date: 5 July 2021

Review

An Update on Screening Strategies for Gestational Diabetes Mellitus: A Narrative Review

Minschart C, Beunen K, Benhalima K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3047-3076

Published Date: 5 July 2021

Cardiovascular Risk Prediction, Glycemic Control, and Determinants in Diabetic and Hypertensive Patients in Massawa Hospital, Eritrea: Cross-Sectional Study on 600 Subjects

Tesfai B, Kibreab F, Dawit A, Mekonen Z, Ghebrezghi S, Kefele S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3035-3046

Published Date: 5 July 2021

External Validation of the Prognostic Prediction Model for 4-Year Risk of Metabolic Syndrome in Adults: A Retrospective Cohort Study

Zhang H, Chen D, Shao J, Zou P, Cui N, Tang L, Wang X, Wang D, Ye Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3027-3034

Published Date: 1 July 2021

Associations of GWAS-Supported Non-MHC Genes with Autoimmune Thyroiditis in Patients with Type 1 Diabetes

Liang J, Liang G, Liu Z, Cai H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3017-3026

Published Date: 1 July 2021

Review

Oral Health Messiers: Diabetes Mellitus Relevance

Ahmad R, Haque M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:3001-3015

Published Date: 1 July 2021

Lipophagy: A New Perspective of Natural Products in Type 2 Diabetes Mellitus Treatment

Huang M, Yang X, Wang Z, Long J, Wang A, Zhang Y, Yan D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2985-2999

Published Date: 30 June 2021

The Incidence of Metabolic Syndrome and the Valid Blood Pressure Cutoff Value for Predicting Metabolic Syndrome Within the Normal Blood Pressure Range in the Population Over 40 Years Old in Guiyang, China

Ma L, Li H, Zhuang H, Zhang Q, Peng N, Hu Y, Han N, Yang Y, Shi L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2973-2983

Published Date: 30 June 2021

Review

An Overview of Similarities and Differences in Metabolic Actions and Effects of Central Nervous System Between Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) and Sodium Glucose Co-Transporter-2 Inhibitors (SGLT-2is)

Wen S, Nguyen T, Gong M, Yuan X, Wang C, Jin J, Zhou L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2955-2972

Published Date: 29 June 2021

Clinical Trial Report

Lifestyle and Work-Related Factors Associated with Work Ability and Work Participation for People with Obesity: A Prospective Observational Study After Vocational Rehabilitation

Linge AD, Jensen C, Laake P, Bjørkly SK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2943-2954

Published Date: 29 June 2021

Evaluation Through the Optical Coherence Tomography Analysis of the Influence of Non-Alcoholic Fatty Liver Disease on the Gingival Inflammation in Periodontal Patients

Surlin P, Didilescu AC, Lazar L, Arsenie CC, Camen A, Popescu DM, Gheorghe DN, Osiac E, Rogoveanu I

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2935-2942

Published Date: 29 June 2021

Original Research

Efficacy of a Combination of Metformin and Vildagliptin in Comparison to Metformin Alone in Type 2 Diabetes Mellitus: A Multicentre, Retrospective, Real-World Evidence Study

Mohan V, Zargar A, Chawla M, Joshi A, Ayyagari U, Sethi B, Gaurav K, Patted URH, Bhagat SV, Mane AI

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2925-2933

Published Date: 29 June 2021

Thymoquinone Preserves Pancreatic Islets Structure Through Upregulation of Pancreatic β-Catenin in Hypothyroid Rats

Faddladdeen K, Ali SS, Bahshwan S, Ayuob N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2913-2924

Published Date: 29 June 2021

Quality of Life Differences in Pre- and Post-Educational Treatment in Type 1 Diabetes Mellitus During COVID-19

Rochmah N, Faizi M, Hisbiyah Y, Triastuti IW, Wicaksono G, Endaryanto A, Soetjipto

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2905-2911

Published Date: 28 June 2021

Foveal Avascular Zone Does Not Correspond to Choroidal Characteristics in Patients with Diabetic Retinopathy: A Single-Center Cross-Sectional Analysis

Sidorczuk P, Pieklarz B, Konopinska J, Saeed E, Mariak Z, Dmuchowska D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2893-2903

Published Date: 28 June 2021

Original Research

Decreased Physiological Serum Total Bile Acid Concentrations in Patients with Type 2 Diabetic Peripheral Neuropathy

Yan P, Wan Q, Zhang Z, Tang Q, Wu Y, Xu Y, Miao Y, Zhao H, Liu R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2883-2892

Published Date: 28 June 2021

A Clinical Study on Gestational Diabetes Mellitus and the Hearing of Newborns

Zhou JH, Yu K, Ding H, Zhu ZH, Han LH, Zhang T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2879-2882

Published Date: 28 June 2021

Relationship Between Serum Neopterin Level and Peripheral Arterial Plaque in Patients with Type 2 Diabetes

Wan RH, Yuan Y, Hao W, Zheng LY, Lu J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2871-2878

Published Date: 28 June 2021

Changes in Body Weight, Dysglycemia, and Dyslipidemia After Moderately Low-Carbohydrate Diet Education (LOCABO Challenge Program) Among Workers in Japan

Yamada S, Inoue G, Ooyane H, Nishikawa H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2863-2870

Published Date: 23 June 2021

A Non-Linear Association of High-Density Lipoprotein Cholesterol with All-Cause and Cause-Specific Mortality in Diabetic Patients

Yan Y, Chen J, Huang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2851-2862

Published Date: 22 June 2021

High-Normal Serum Thyrotropin Levels Increased the Risk of Non-Alcoholic Fatty Liver Disease in Euthyroid Subjects with Type 2 Diabetes

Tan Y, Tang X, Mu P, Yang Y, Li M, Nie Y, Li H, Zhu Y, Chen Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2841-2849

Published Date: 22 June 2021

Association Between the Triglyceride–Glucose Index and Outcomes of Nonalcoholic Fatty Liver Disease: A Large-Scale Health Management Cohort Study

Liu J, Guan L, Zhao M, Li Q, Song A, Gao L, Lin H, Zhao J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2829-2839

Published Date: 21 June 2021

Review

Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges

Vilarrasa N, San Jose P, Rubio MA, Lecube A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2807-2827

Published Date: 21 June 2021

Artificial Flora Algorithm-Based Feature Selection with Gradient Boosted Tree Model for Diabetes Classification

P N, P D, Mansour RF, Almazroa A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2789-2806

Published Date: 21 June 2021

A Compendium of Perspectives on Diabetes: A Challenge for Sustainable Health in the Modern Era

Verma AK, Goyal Y, Bhatt D, Dev K, Alsahli MA, Rahmani AH, Almatroudi A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2775-2787

Published Date: 17 June 2021

The Association Between Obesity and Social Isolation as Well as Loneliness in the Adult Population: A Systematic Review

Hajek A, Kretzler B, König HH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2765-2773

Published Date: 17 June 2021

Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice

Chen X, Yang K, Jin X, Meng Z, Liu B, Yu H, Lu P, Wang K, Fan Z, Tang Z, Zhang F, Liu C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2753-2764

Published Date: 17 June 2021

Associations Between Serum Free Fatty Acid Levels and Incident Diabetes in a 3-Year Cohort Study

Li Q, Zhao M, Wang Y, Zhong F, Liu J, Gao L, Zhao J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2743-2751

Published Date: 17 June 2021

Secreted Frizzled-Related Protein 5 is Associated with Glucose and Lipid Metabolism Related Metabolic Syndrome Components Among Adolescents in Northeastern China

Bai Y, Du Q, Jiang R, Zhang L, Du R, Wu N, Li P, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2735-2742

Published Date: 17 June 2021

Influence of Low Total Triiodothyronine Levels on Bone Turnover Markers in Type 2 Diabetes Mellitus

Li Z, Yu X, Ren L, Wang Z, Wang F, Jia Y, Chen S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2727-2733

Published Date: 16 June 2021

Evaluation of the Efficacy of the Hospital Glycemic Management System for Patients with Malignant Tumors and Hyperglycemia

Jiang J, Pu D, Hu R, Hu M, Wu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2717-2725

Published Date: 16 June 2021

Review

Psychosocial Determinants of Treatment Adherence in Patients with Type 2 Diabetes – A Review

Świątoniowska-Lonc N, Tański W, Polański J, Jankowska-Polańska B, Mazur G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2701-2715

Published Date: 16 June 2021

Current Practices and Gaps in Management of Dyslipidemia in Type 2 Diabetes Mellitus (T2DM) in Accordance with American Diabetes Association (ADA) Guidelines: A Subset Analysis from a Real-World, Cross-Sectional Observational Study (LEADD Study)

Das AK, Saboo B, Unnikrishnan AG

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2693-2700

Published Date: 15 June 2021

Associations of Thyroid Hormone Levels and Macrovascular Complications in Euthyroid Type 2 Diabetic Patients

Hu Y, Yan Z, Pan C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2683-2691

Published Date: 15 June 2021

The Association of Serum Uric Acid with Beta-Cell Function and Insulin Resistance in Nondiabetic Individuals: A Cross-Sectional Study

Yu P, Huang L, Wang Z, Meng X, Yu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2673-2682

Published Date: 14 June 2021

Transition Patterns of Weight Status and Their Predictive Lipid Markers Among Chinese Adults: A Longitudinal Cohort Study Using the Multistate Markov Model

Tang X, Zhang H, Zhao Y, Lei F, Liu Q, Hu D, Li G, Song G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2661-2671

Published Date: 14 June 2021

The Efficacy and Safety of Chinese Medicine Fufang Zhenzhu Tiaozhi Capsule (FTZ) in the Treatment of Diabetic Coronary Heart Disease: Study Protocol for Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Wang L, Xiang L, Piao S, Gong X, Zhou W, Feng W, Li H, Li L, Wei A, Zhu Q, Rong X, Guo J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2651-2659

Published Date: 14 June 2021

Nomogram Predicting the Risk of Progression from Prediabetes to Diabetes After a 3-Year Follow-Up in Chinese Adults

Liang K, Guo X, Wang C, Yan F, Wang L, Liu J, Hou X, Li W, Chen L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2641-2649

Published Date: 14 June 2021

Association Between Different Obesity Patterns and the Risk of Developing Type 2 Diabetes Mellitus Among Adults in Eastern China: A Cross-Sectional Study

Lu Y, Yang H, Xu Z, Tang X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2631-2639

Published Date: 10 June 2021

Risk of Thyroid Cancer Associated with Use of Liraglutide and Other Antidiabetic Drugs in a US Commercially Insured Population

Funch D, Mortimer K, Ziyadeh NJ, Seeger JD, Zhou L, Ng E, Ross D, Major-Pedersen A, Bosch-Traberg H, Gydesen H, Dore DD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2619-2629

Published Date: 10 June 2021

Identification of Significant Predictors for the Need of Insulin Therapy and Onset of Postpartum Impaired Glucose Tolerance in Gestational Diabetes Mellitus Patients

Wang T, Yin W, Huang Y, Zhang Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2609-2617

Published Date: 10 June 2021

“Adjusting Internal Organs and Dredging Channel” Electroacupuncture Ameliorates Insulin Resistance in Type 2 Diabetes Mellitus by Regulating the Intestinal Flora and Inhibiting Inflammation

Zhang L, Chen X, Wang H, Huang H, Li M, Yao L, Ma S, Zhong Z, Yang H, Wang H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2595-2607

Published Date: 9 June 2021

A Nonlinear Relationship Between Serum 25-Hydroxyvitamin D and Urine Albumin to Creatinine Ratio in Type 2 Diabetes: A Cross-Sectional Study in China

Liang Q, Hu H, Wu H, Chen X, Wang W, Le Y, Yang S, Jia L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2581-2593

Published Date: 9 June 2021

Prognostic Factors Related to the Mortality Rate of Acute-on-Chronic Liver Failure Patients

Zhang J, Li J, Chen Y, Ding M, Duan Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2573-2580

Published Date: 9 June 2021

Short-Term Changes in Metabolically Healthy Overweight/Obesity Status Impact the Susceptibility to Type 2 Diabetes in Chinese Adults

Min J, Hu X, Zhang J, Zeng T, Wang Y, Tian S, Liu G, Zhong X, Qiu K, Peng M, Chen L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2561-2571

Published Date: 9 June 2021

Emerging Roles of Long Non-Coding RNAs in Diabetic Foot Ulcers

Yan C, Chen J, Yang X, Li W, Mao R, Chen Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2549-2560

Published Date: 9 June 2021

Non-Enzymatic Glycation of Transferrin and Diabetes Mellitus

Ma Y, Cai J, Wang Y, Liu F, Fu S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2539-2548

Published Date: 8 June 2021

Berberine Ameliorates Hepatic Insulin Resistance by Regulating microRNA-146b/SIRT1 Pathway

Sui M, Jiang X, Sun H, Liu C, Fan Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2525-2537

Published Date: 4 June 2021

miR-140-5p Aggravates Insulin Resistance via Directly Targeting GYS1 and PPP1CC in Insulin-Resistant HepG2 Cells

Li X, Ye Y, Wang B, Zhao S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2515-2524

Published Date: 4 June 2021

Original Research

Prevalence of the Metabolic Syndrome Among Batswana Adults in Urban and Semi-Urban Gaborone

Tladi D, Mokgatlhe L, Nell T, Shaibu S, Mitchell R, Mokgothu C, Gabonthone T, Hubona O

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2505-2514

Published Date: 4 June 2021

Maternal Plasma Betaine in Middle Pregnancy Was Associated with Decreased Risk of GDM in Twin Pregnancy: A Cohort Study

Gong X, Du Y, Li X, Yang J, Zhang X, Wei Y, Zhao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2495-2504

Published Date: 3 June 2021

Relationship Between Vitamin D Status and the Relevant Parameters of Glucose in Patients with Type 2 Diabetes

Tran Huu TT, Tran HD, Tran TN, Hoang BB

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2489-2494

Published Date: 3 June 2021

Blood Levels of Glycated Hemoglobin, D-Dimer, and Fibrinogen in Diabetic Retinopathy

Zhao H, Zhang LD, Liu LF, Li CQ, Song WL, Pang YY, Zhang YL, Li D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2483-2488

Published Date: 2 June 2021

Estimating the Risk of Insulin Requirement in Women Complicated by Gestational Diabetes Mellitus: A Clinical Nomogram

Du R, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2473-2482

Published Date: 1 June 2021

Associations of TCF7L2 rs11196218 (A/G) and GLP-1R rs761386 (C/T) Gene Polymorphisms with Obesity in Chinese Population

Xu T, Liu M, Liu Q, Wang B, Wang M, Qu M, Chen X, Wu J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2465-2472

Published Date: 1 June 2021

Joint Predictors of Hypertension and Type 2 Diabetes Among Adults Under Treatment in Amhara Region (North-Western Ethiopia)

Tegegne AS

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2453-2463

Published Date: 1 June 2021

Early Prediction Model of Gestational Hypertension by Multi-Biomarkers Before 20 Weeks Gestation

Zhou C, Song C, Huang X, Chen S, Long Y, Zeng S, Yang H, Jiang M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2441-2451

Published Date: 31 May 2021

Scutellaria barbata D. Don Polysaccharides Inhibit High Glucose-Induced Proliferation and Angiogenesis of Retinal Vascular Endothelial Cells

Li W, Xiao H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2431-2440

Published Date: 31 May 2021

Prospective Association of Novel Metabolic Indices with Metabolic Syndrome in Middle-Aged and Elderly Chinese

Li JY, Yang J, Qi XY, Luo YH, Wang YD, Liao ZZ, Ran L, Xiao XH, Liu JH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2427-2430

Published Date: 28 May 2021

Original Research

Lipid Accumulation Product is Associated with Urinary Albumin-creatinine Ratio in Chinese Prediabitic Population: A Report from the REACTION Study

Liu Y, Wang Y, Wang J, Chen K, Jin L, Wang W, Gao Z, Tang X, Yan L, Wan Q, Luo Z, Qin G, Chen L, Mu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2415-2425

Published Date: 28 May 2021

Association Between Neck Circumference and Microalbuminuria in Community Residents

Jian C, Xu Y, Shen Y, Wang Y, Ma X, Bao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2407-2414

Published Date: 28 May 2021

Association Between Thyroid Hormone Levels and Advanced Liver Fibrosis in Patients with Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease

Du J, Chai S, Zhao X, Sun J, Zhang X, Huo L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2399-2406

Published Date: 26 May 2021

Psoriasis Exacerbates the State of Insulin Resistance in Patients with Type 2 Diabetes

Wen S, Liu C, Li Y, Pan J, Nguyen T, Zhou L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2389-2397

Published Date: 26 May 2021

Peripheral Vascular Disease Susceptibility Based on Diabetes Mellitus and rs17367504 Polymorphism of the MTHFR Gene

Liu YT, Lin CC, Wang L, Nfor ON, Hsu SY, Lung CC, Tantoh DM, Chang HR, Liaw YP

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2381-2388

Published Date: 26 May 2021

Diabetes Mellitus as a Risk Factor for Progression from Acute Kidney Injury to Acute Kidney Disease: A Specific Prediction Model

Zhao H, Liang L, Pan S, Liu Z, Liang Y, Qiao Y, Liu D, Liu Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2367-2379

Published Date: 25 May 2021

The Association Between Insulin Resistance, Leptin, and Resistin and Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients with Different Body Mass Indexes

Huang J, Peng X, Dong K, Tao J, Yang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2357-2365

Published Date: 24 May 2021

Low TSH Levels Within Euthyroid Range Could Play a Negative Role on Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes

Liu C, Pan J, Wen S, Nguyen T, Xu D, Wang C, Yuan X, Wen Z, Zhou L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2349-2355

Published Date: 24 May 2021

[Gly14]-Humanin Ameliorates High Glucose-Induced Apoptosis by Inhibiting the Expression of MicroRNA-155 in Endothelial Microparticles

Shen MY, Wang M, Liu Z, Wang S, Xie Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2335-2347

Published Date: 24 May 2021

Use of Eye Care Service and Associated Factors Among Adult Diabetic Patients Attending at Diabetic Clinics in Two Referral Hospitals, Northeast Ethiopia

Ahmed TM, Demilew KZ, Tegegn MT, Hussen MS

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2325-2333

Published Date: 24 May 2021

Predictors of Poor Plasma Glucose Maintenance in Type II Diabetic People with Ophthalmic Complication: The Case of Dessie Hospitals in Ethiopia

Abdu Seid M, Dagnew B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2317-2324

Published Date: 24 May 2021

Diet Sugar-Free Carbonated Soda Beverage, Non-Caloric Flavors Consumption, and Diabetic Retinopathy: Any Linkage

Mirghani H, Alali N, Albalawi H, ALselaimy R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2309-2315

Published Date: 24 May 2021

Salusin-β Mediates High Glucose-Induced Inflammation and Apoptosis in Retinal Capillary Endothelial Cells via a ROS-Dependent Pathway in Diabetic Retinopathy

Wang H, Zhang M, Zhou H, Cao L, Zhou J, Chen Q, Zhang X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2291-2308

Published Date: 21 May 2021

Diabetes Concordant Comorbidities and Associated Factors Among Adult Diabetic Out-Patients at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia: a Cross-Sectional Study

Ejeta A, Abdosh T, Hawulte B, Lamessa A, Belete Fite M, Fekadu G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2281-2289

Published Date: 21 May 2021

Roux-en-Y Gastric Bypass Improves Hepatic Glucose Metabolism Involving Upregulation of Sirt1 in Type 2 Diabetes Mellitus

Su C, Cheng Q, Wang L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2269-2280

Published Date: 20 May 2021

Epidermal Growth Factor Protects Against High Glucose-Induced Podocyte Injury Possibly via Modulation of Autophagy and PI3K/AKT/mTOR Signaling Pathway Through DNA Methylation

Sun Y, Deng M, Ke X, Lei X, Ju H, Liu Z, Bai X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2255-2268

Published Date: 19 May 2021

Serum Micro-RNA-122 Level as a Simple Noninvasive Marker of MAFLD Severity

Hegazy MA, Abd ALgwad I, Abuel Fadl S, Sayed Hassan M, Ahmed Rashed L, Hussein MA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2247-2254

Published Date: 19 May 2021

Evaluation of Self-Care Practice and Its Associated Factors in Adult Diabetic Patients, Ayder Diabetic Clinic, Mekelle, Ethiopia

Weledegebriel M, Mulugeta A, Hailu A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2239-2245

Published Date: 18 May 2021

Development and Internal Validation of a Prognostic Model for 4-Year Risk of Metabolic Syndrome in Adults: A Retrospective Cohort Study

Zhang H, Chen D, Shao J, Zou P, Cui N, Tang L, Wang D, Ye Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2229-2237

Published Date: 18 May 2021

Perspectives

Bangladesh Endocrine Society (BES) Position Statement for Management of Diabetes and Other Endocrine Diseases in Patients with COVID-19

Pathan F, Selim S, Fariduddin M, Rahman MH, Ashrafuzzaman SM, Afsana F, Qureshi NK, Hossain T, Saifuddin M, Kamrul-Hasan AB, Mir AS

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2217-2228

Published Date: 18 May 2021

The Distribution Pattern of Traditional Chinese Medicine Syndromes in 549 Patients with Type 2 Diabetes

Zhang GD, Liu XX, Liang JL, Hu QM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2209-2216

Published Date: 17 May 2021

Correlation Between the Distribution of Abdominal, Pericardial and Subcutaneous Fat and Muscle and Age and Gender in a Middle-Aged and Elderly Population

Ni X, Jiao L, Zhang Y, Xu J, Zhang Y, Zhang X, Du Y, Sun Z, Wang S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2201-2208

Published Date: 17 May 2021

Diabetes Mellitus Promotes Atrial Structural Remodeling and PARP-1/Ikkα/NF-κB Pathway Activation in Mice

Meng T, Wang J, Tang M, Liu S, Ding L, Yan Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2189-2199

Published Date: 17 May 2021

Association Between Gut Akkermansia and Metabolic Syndrome is Dose-Dependent and Affected by Microbial Interactions: A Cross-Sectional Study

Zhou Q, Pang G, Zhang Z, Yuan H, Chen C, Zhang N, Yang Z, Sun L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2177-2188

Published Date: 17 May 2021

Prevalence of Prediabetes and Undiagnosed Diabetes Among Kuwaiti Adults: A Cross-Sectional Study

Mohammad A, Ziyab AH, Mohammad T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2167-2176

Published Date: 17 May 2021

Information-Seeking Behavior and Its Associated Factors Among Patients with Diabetes in a Resource-Limited Country: A Cross-Sectional Study

Mengiste M, Ahmed MH, Bogale A, Yilma T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2155-2166

Published Date: 17 May 2021

Original Research

Does Patients’ Perception Affect Self-Care Practices? The Perspective of Health Belief Model

Melkamu L, Berhe R, Handebo S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2145-2154

Published Date: 13 May 2021

Yes-Associated Protein is Involved in Myocardial Fibrosis in Rats with Diabetic Cardiomyopathy

Hu M, Wang H, Li S, Yan F, Fu C, Li L, Yu Y, Xiong J, Dong B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2133-2143

Published Date: 13 May 2021

Antidiabetic and Nephroprotective Effects of Polysaccharide Extract from the Seaweed Caulerpa racemosa in High Fructose-Streptozotocin Induced Diabetic Nephropathy

Cao M, Li Y, Famurewa AC, Olatunji OJ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2121-2131

Published Date: 12 May 2021

Diabetic Self-Care Knowledge and Associated Factors Among Adult Diabetes Mellitus Patients on Follow-Up Care at North Shewa Zone Government Hospitals, Oromia Region, Ethiopia, 2020

Zerihun Sahile L, Benayew Shifraew M, Zerihun Sahile M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2111-2119

Published Date: 12 May 2021

A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells

Wu R, Wang H, Huangfu J, Xiao R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2103-2110

Published Date: 11 May 2021

Derivation and Validation of a Prediction Model for Predicting the 5-Year Incidence of Type 2 Diabetes in Non-Obese Adults: A Population-Based Cohort Study

Cai XT, Ji LW, Liu SS, Wang MR, Heizhati M, Li NF

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2087-2101

Published Date: 11 May 2021

Interhemispheric Functional Connectivity Alterations in Diabetic Optic Neuropathy: A Resting-State Functional Magnetic Resonance Imaging Study

Tan SW, Cai GQ, Li QY, Guo Y, Pan YC, Zhang LJ, Ge QM, Shu HY, Zeng XJ, Shao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2077-2086

Published Date: 11 May 2021

Weight Gain After 20 Years of Age is Associated with Unfavorable Lifestyle and Increased Prevalence of Metabolic Disorders

Takebe N, Tanno K, Ohmomo H, Hangai M, Oda T, Hasegawa Y, Takanashi N, Sasaki R, Shimizu A, Sasaki A, Sakata K, Sasaki M, Ishigaki Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2065-2075

Published Date: 20 May 2021

Relationship Between Long-Term Objectively Measured Physical Activity and Glycemic Control in Type 2 Diabetes Mellitus Patients: A Prospective Cohort Study

Masuda H, Ishiyama D, Yamada M, Iwashima F, Kimura Y, Otobe Y, Tani N, Suzuki M, Nakajima H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2057-2063

Published Date: 7 May 2021

Original Research

The Relationship Between the Metabolic Syndrome and the Place of Residence in the Local Community on the Example of the Janów Lubelski District in Eastern Poland: A Population-Based Study

Nowicki GJ, Ślusarska B, Naylor K, Prystupa A, Rudnicka-Drożak E, Halyuk U, Pokotylo P

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2041-2056

Published Date: 6 May 2021

Comparison of Clinical Characteristics Between Obese and Non-Obese Patients with Nonalcoholic Fatty Liver Disease (NAFLD)

Li Y, Chen Y, Tian X, Zhang S, Jiao J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2029-2039

Published Date: 6 May 2021

Risk Factors for Major Amputation in Diabetic Foot Ulcer Patients

Lu Q, Wang J, Wei X, Wang G, Xu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2019-2027

Published Date: 4 May 2021

Assessment of Serum Vitamin B12 and Folate Levels and Macrocytosis in Patients with Type 2 Diabetes Mellitus on Metformin Attending Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A Cross-Sectional Study

Wale Tesega W, Genet S, Netasan G, Tarekegn G, Girma F, Chalchisa D, Belay Y, Geto Z, Asmamaw Dejenie T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:2011-2018

Published Date: 3 May 2021

Original Research

Understandings, Attitudes, and Barriers About Diabetes Care: Analysis of Factors Influencing Community Pharmacists in China

Wang J, Pei Y, Yu F, Kang Z, Zheng Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1999-2009

Published Date: 3 May 2021

Eating Behavior Changes of People with Obesity During the COVID-19 Pandemic

Bayram Deger V

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1987-1997

Published Date: 3 May 2021

Original Research

Prevalence and Risk Factors of Type 2 Diabetes and Prediabetes Among 53,288 Middle-Aged and Elderly Adults in China: A Cross-Sectional Study

Xia M, Liu K, Feng J, Zheng Z, Xie X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1975-1985

Published Date: 3 May 2021

The Association Between Sarcopenic Obesity and Hypertension, Diabetes, and Abnormal Lipid Metabolism in Chinese Adults

Yin T, Zhang JX, Wang FX, Zhao JH, Zhao Y, Liu L, Liu XY, Zhang YH, Zhao Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1963-1973

Published Date: 30 April 2021

Physical Exercise is Associated with Glycemic Control among Women with Gestational Diabetes Mellitus: Findings from a Prospective Cohort in Shanghai, China

Wang R, Yang Q, Sun T, Qiang Y, Li X, Li H, Tang Y, Yang L, Sun J, Li B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1949-1961

Published Date: 30 April 2021

The Relationship Between Hemoglobin Glycation Variation Index and Vitamin D in Type 2 Diabetes Mellitus

Li Z, Wang F, Jia Y, Guo F, Chen S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1937-1948

Published Date: 30 April 2021

Relationship Between Metabolic Syndrome and Cognitive Function: A Population-Based Study of Middle-Aged and Elderly Adults in Rural China

Zhan C, Wang Q, Liu J, Wang L, Chen Z, Pang H, Tu J, Ning X, Wang J, Fei S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1927-1935

Published Date: 30 April 2021

Knowledge, Attitude and Practice Towards Insulin-Self Administration Among Diabetic Patients Attending Bedele Hospital, Southwest Ethiopia, 2019/2020

Fego MW, Yasin JT, Aga GM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1919-1925

Published Date: 29 April 2021

Association of Insulin Glargine Treatment with Bone Mineral Density in Patients with Type 2 Diabetes Mellitus

Liu D, Bai JJ, Yao JJ, Wang YB, Chen T, Xing Q, Bai R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1909-1917

Published Date: 29 April 2021

T-Natural Killers and Interferon Gamma/Interleukin 4 in Augmentation of Infection in Foot Ulcer in Type 2 Diabetes

Hammad R, Elmadbouly AA, Ahmad IH, Mohammed SA, Farouk N, Futooh Z, Alfy MO, Abozaid S, Mohamed EF, Kotb FM, Abdelbadea A, Seliem N, Elshafei A, Mashaal A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1897-1908

Published Date: 29 April 2021

Forsythoside A Alleviates High Glucose-Induced Oxidative Stress and Inflammation in Podocytes by Inactivating MAPK Signaling via MMP12 Inhibition

Quan X, Liu H, Ye D, Ding X, Su X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1885-1895

Published Date: 28 April 2021

Astragaloside IV Alleviates Liver Inflammation, Oxidative Stress and Apoptosis to Protect Against Experimental Non-Alcoholic Fatty Liver Disease

Liang XY, Hong Ff, Yang SL

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1871-1883

Published Date: 28 April 2021

Nutritional Effects of the Enteral Nutritional Formula on Regulation of Gut Microbiota and Metabolic Level in Type 2 Diabetes Mellitus Mice

Wei T, Jia Y, Xue W, Ma M, Wu W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1855-1869

Published Date: 28 April 2021

Microbial Ecosystem in Diabetes Mellitus: Consideration of the Gastrointestinal System

Yehualashet AS, Yikna BB

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1841-1854

Published Date: 28 April 2021

The Mental Status in Patients with Diabetes Mellitus Admitted to a Diabetes Clinic After Presenting in the Emergency Room: The Application of the SCL-90 Scale

Albai O, Frandes M, Timar R, Timar B, Anghel T, Avram VF, Sima A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1833-1840

Published Date: 28 April 2021

Correlation Between 25-Hydroxyvitamin D Level and Cardiac Diastolic Dysfunction in Chinese Adults with Early-Onset Type 2 Diabetes Mellitus: A Cross-Sectional Study

Xiu L, Yao X, Jiang T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1823-1831

Published Date: 28 April 2021

A Comparative Study on Insulin Secretion, Insulin Resistance and Thyroid Function in Patients with Polycystic Ovary Syndrome with and without Hashimoto’s Thyroiditis

Zhao H, Zhang Y, Ye J, Wei H, Huang Z, Ning X, Fu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1817-1821

Published Date: 28 April 2021

Association of Glycated Albumin/Glycosylated Hemoglobin Ratio with Blood Glucose Fluctuation and Long-Term Blood Glucose Control in Patients with Type 2 Diabetes Mellitus

Wang BR, Yao JT, Zheng H, Li QM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1809-1815

Published Date: 27 April 2021

A Wearable Gait Analysis System Used in Type 2 Diabetes Mellitus Patients: A Case–Control Study

Tian T, Wang C, Xu Y, Bai Y, Wang J, Long Z, Wang X, Zhou L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1799-1808

Published Date: 23 April 2021

The Associations of Perceived and Oxidative Stress with Hypertension in a Cohort of Police Officers

Janczura M, Rosa R, Dropinski J, Gielicz A, Stanisz A, Kotula-Horowitz K, Domagala T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1783-1797

Published Date: 23 April 2021

Assessment for the Correlation Between Diabetic Retinopathy and Metabolic Syndrome: A Cross-Sectional Study

Sun Q, Tang L, Zeng Q, Gu M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1773-1781

Published Date: 22 April 2021

Change in Urine Albumin-to-Creatinine Ratio and Risk of Diabetic Peripheral Neuropathy in Type 2 Diabetes: A Retrospective Cohort Study

Zhong M, Yang YR, Zhang YZ, Yan SJ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1763-1772

Published Date: 22 April 2021

Association Between Metabolic Associated Fatty Liver Disease and Chronic Kidney Disease: A Cross-Sectional Study from NHANES 2017–2018

Deng Y, Zhao Q, Gong R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1751-1761

Published Date: 22 April 2021

LncRNA PVT1 Regulates High Glucose-Induced Viability, Oxidative Stress, Fibrosis, and Inflammation in Diabetic Nephropathy via miR-325-3p/Snail1 Axis

Qin B, Cao X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1741-1750

Published Date: 19 April 2021

Original Research

Physical Activity of Type 2 Diabetes Mellitus Patients and Non-Diabetes Participants in Yangon, Myanmar: A Case-Control Study Applying the International Physical Activity Questionnaires (IPAQ-S)

Ahmad I, Aung MN, Ueno S, Khin ET, Latt TS, Moolphate S, Yuasa M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1729-1739

Published Date: 20 April 2021

Perspectives

Consensus on Medical Nutrition Therapy for Diabesity (CoMeND) in Adults: A South Asian Perspective

Kapoor N, Sahay R, Kalra S, Bajaj S, Dasgupta A, Shrestha D, Dhakal G, Tiwaskar M, Sahay M, Somasundaram N, Reddy R, Bhattacharya S, Reddy VB, Viswanathan V, Krishnan D, Baruah M, Das AK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1703-1728

Published Date: 16 April 2021

Improvement in Cardiometabolic Risk Factors During Smoking Cessation Treatment in Patients with Type 2 Diabetes: A Retrospective Cohort Study

Chen HJ, Huang WH, Chan HL, Hwang LC

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1695-1702

Published Date: 16 April 2021

Vitamin D/VDR Protects Against Diabetic Kidney Disease by Restoring Podocytes Autophagy

Song Z, Xiao C, Jia X, Luo C, Shi L, Xia R, Zhu J, Zhang S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1681-1693

Published Date: 16 April 2021

The Involvement of Selenium in Type 2 Diabetes Development Related to Obesity and Low Grade Inflammation

Wongdokmai R, Shantavasinkul PC, Chanprasertyothin S, Panpunuan P, Matchariyakul D, Sritara P, Sirivarasai J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1669-1680

Published Date: 14 April 2021

Incidence of Cardiovascular Complications and Nephropathy in Patients with Type 2 Diabetes in a Primary Care Setting in Riyadh, Saudi Arabia

Alsaidan M, Alkhenizan A, Amber ST, Alsoghayer S, AlFakhri L, Abudaia J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1663-1667

Published Date: 15 April 2021

Astragaloside IV Inhibits Mitochondrial-Dependent Apoptosis of the Dorsal Root Ganglion in Diabetic Peripheral Neuropathy Rats Through Modulation of the SIRT1/p53 Signaling Pathway

Ben Y, Hao J, Zhang Z, Xiong Y, Zhang C, Chang Y, Yang F, Li H, Zhang T, Wang X, Xu Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1647-1661

Published Date: 14 April 2021

Atorvastatin Regulates MALAT1/miR-200c/NRF2 Activity to Protect Against Podocyte Pyroptosis Induced by High Glucose

Zuo Y, Chen L, He X, Ye Z, Li L, Liu Z, Zhou S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1631-1645

Published Date: 13 April 2021

A Clinical Study on the Association of Sodium-Glucose Cotransporter 2 Inhibitors and Acute Kidney Injury Among Diabetic Chinese Population

Shen L, Yang H, Fang X, Huang H, Yao W, Chen D, Shen Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1621-1630

Published Date: 13 April 2021

Visceral Obesity-Related Indices in the Identification of Individuals with Metabolic Syndrome Among Different Ethnicities in Xinjiang, China

Zhang X, Ding Y, Shao Y, He J, Ma J, Guo H, Keerman M, Liu J, Si H, Guo S, Ma R

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1609-1620

Published Date: 12 April 2021

Serum Human Epididymis Protein 4 is a Potential Biomarker for Early Chronic Kidney Disease in an Obese Population

Tan S, Zeng Y, Kuang S, Li J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1601-1608

Published Date: 16 April 2021

Differences in Several Factors in the Development of Erosive Esophagitis Among Patients at Various Stages of Metabolic Syndrome: A Cross-Sectional Study

Sogabe M, Okahisa T, Kurihara T, Kagawa M, Kagemoto K, Kida Y, Tomonari T, Taniguchi T, Okamoto K, Miyamoto H, Sato Y, Nakasono M, Takayama T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1589-1600

Published Date: 12 April 2021

Anaemia and Related Nutritional Deficiencies in Chinese Patients with Obesity, 12 Months Following Laparoscopic Sleeve Gastrectomy

Zhang C, Chen X, Li J, Liu Z, Liu W, Zhang J, Zhou Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1575-1587

Published Date: 12 April 2021

Incidence and Survival of Hepatocellular Carcinoma in Type 2 Diabetes Patients with Cirrhosis Who Were Treated with and without Metformin

Tangjarusritaratorn T, Tangjittipokin W, Kunavisarut T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1563-1574

Published Date: 9 April 2021

Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA

Sutkowska E, Ostrowska M, Sutkowska M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1557-1561

Published Date: 9 April 2021

The Triglyceride–Glucose Index is Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes: A Hospital-Based, Nested, Case–Control Study

Yao L, Wang X, Zhong Y, Wang Y, Wu J, Geng J, Zhou Y, Chen J, Guan P, Xu Y, Chen L, Liu L, Hu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1547-1555

Published Date: 9 April 2021

Significant Association Between Left Ventricular Diastolic Dysfunction, Left Atrial Performance and Liver Stiffness in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease

Parvanescu T, Vitel A, Sporea I, Mare R, Buz B, Bordejevic DA, Tomescu MC, Arnautu SF, Morariu VI, Citu IM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1535-1545

Published Date: 9 April 2021

Aspects to Consider for a More Useful, Discriminative Predictive Tool for CAP Mortality in T2DM [Letter]

Geltser D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1533-1534

Published Date: 7 April 2021

DPP-4 Inhibitors Have Different Effects on Endothelial Low-Grade Inflammation and on the M1-M2 Macrophage Polarization Under Hyperglycemic Conditions

De Nigris V, Prattichizzo F, Iijima H, Ceriello A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1519-1531

Published Date: 6 April 2021

Insulin, but Not Metformin, Supports Wound Healing Process in Rats with Streptozotocin-Induced Diabetes

Mieczkowski M, Mrozikiewicz-Rakowska B, Siwko T, Bujalska-Zadrozny M, de Corde-Skurska A, Wolinska R, Gasinska E, Grzela T, Foltynski P, Kowara M, Mieczkowska Z, Czupryniak L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1505-1517

Published Date: 6 April 2021

Microbiological Concordance in the Management of Diabetic Foot Ulcer Infections with Osteomyelitis, on the Basis of Cultures of Different Specimens at a Diabetic Foot Center in China

Li X, Cheng Q, Du Z, Zhu S, Cheng C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1493-1503

Published Date: 6 April 2021

Early Predictors in the Onset of Type 2 Diabetes at Different Fasting Blood Glucose Levels

Xie X, Bai G, Liu H, Zhang L, He Y, Qiang D, Zou X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1485-1492

Published Date: 31 March 2021

The Association Between Different Obesity Phenotypes and Liver Fibrosis Scores in Elderly Individuals with Fatty Liver in Taiwan

Lee YS, Hwang LC, Hsu HY, Tsou MT

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1473-1483

Published Date: 30 March 2021

Metabolic Syndrome and Psoriasis: A Case–Control Study in Kabul, Afghanistan

Aalemi AK, Bahain MB, Hamdard AG

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1465-1471

Published Date: 30 March 2021

The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis

Le MT, Tran NQT, Nguyen ND, Nguyen QHV

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1453-1463

Published Date: 29 March 2021

Assessing MicroRNA-375 Levels in Type 2 Diabetes Mellitus (T2DM) Patients and Their First-Degree Relatives with T2DM

Wu X, Li Y, Man B, Li D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1445-1451

Published Date: 29 March 2021

Evaluation of Eight Anthropometric Indices for Identification of Metabolic Syndrome in Adults with Diabetes

Guo X, Ding Q, Liang M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1431-1443

Published Date: 30 March 2021

Attitudes and Awareness Towards Diabetic Retinopathy Among Patients with Diabetes in Amman, Jordan

Al-latayfeh M, Shatnawi R, Al Shdaifat AA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1425-1430

Published Date: 26 March 2021

Original Research

The Relationship of Anti-Mullerian Hormone in Polycystic Ovary Syndrome Patients with Different Subgroups

Ran Y, Yi Q, Li C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1419-1424

Published Date: 25 March 2021

Mesenchymal Stem Cell-Derived Exosomes Carry MicroRNA-125a to Protect Against Diabetic Nephropathy by Targeting Histone Deacetylase 1 and Downregulating Endothelin-1

Hao Y, Miao J, Liu W, Cai K, Huang X, Peng L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1405-1418

Published Date: 25 March 2021

Glutathione S-Transferase (GSTT1 rs17856199) and Nitric Oxide Synthase (NOS2 rs2297518) Genotype Combination as Potential Oxidative Stress-Related Molecular Markers for Type 2 Diabetes Mellitus

Gusti AMT, Qusti SY, Bahijri SM, Toraih EA, Bokhari S, Attallah SM, Alzahrani A, Alshehri WMA, Alotaibi H, Fawzy MS

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1385-1403

Published Date: 25 March 2021

Optimal Cut-Off Values of Visceral Fat Area for Predicting Metabolic Syndrome Among Type 2 Diabetes Patients in Ningbo, China

Yang X, Lin Y, Xu G, Chen Y, Zhou Y, Sun J, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1375-1383

Published Date: 25 March 2021

Asymptomatic Hyperuricemia and Metabolically Unhealthy Obesity: A Cross-Sectional Analysis in the Tianning Cohort

Yu J, Sun H, Zhu J, Wei X, Shi H, Shen B, Ren L, He Y, Zhang R, Zhang M, Peng H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1367-1374

Published Date: 25 March 2021

The Performance of CURB-65 and PSI for Predicting In-Hospital Mortality of Community-Acquired Pneumonia in Patients with Type 2 Diabetes Compared with the Non-Diabetic Population

Ma CM, Wang N, Su QW, Yan Y, Yin FZ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1359-1366

Published Date: 23 March 2021

Patterns of Calcium- and Chloride-Ion Disorders and Predictors among Obese Outpatient Adults in Southern Ethiopia

Timerga A, Haile K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1349-1358

Published Date: 23 March 2021

Identification of Hepatic Steatosis in Premenopausal and Postmenopausal Women Based on Phenotypes Combining Triglyceride Levels and Anthropometric Indices: A Cross-Sectional Study

Liu PJ, Lou HP, Zhu YN

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1339-1347

Published Date: 23 March 2021

Computed Tomography-Estimated Pancreatic Steatosis is Associated with Carotid Plaque in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study from China

Sun P, Fan C, Wang R, Chu T, Sun X, Zhang D, Du X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1329-1337

Published Date: 22 March 2021

Efficacy and Safety of a Decision Support Intervention for Basal Insulin Self-Titration Assisted by the Nurse in Outpatients with T2DM: A Randomized Controlled Trial

Hu X, Deng H, Zhang Y, Guo X, Cai M, Ling C, Li K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1315-1327

Published Date: 22 March 2021

Incidence of Diabetic Retinopathy and Its Predictors Among Newly Diagnosed Type 1 and Type 2 Diabetic Patients: A Retrospective Follow-up Study at Tertiary Health-care Setting of Ethiopia

Debele GR, Kanfe SG, Weldesenbet AB, Ayana GM, Jifar WW, Raru TB

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1305-1313

Published Date: 22 March 2021

Influence of Pain on the Quality of Life and Disease Acceptance in Patients with Complicated Diabetic Foot Syndrome

Krzemińska S, Kostka A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1295-1303

Published Date: 19 March 2021

Long-Term Visual Function Effects of Pan-Retinal Photocoagulation in Diabetic Retinopathy and Its Impact in Real Life

Baptista PM, Marta AA, Heitor J, José D, Almeida D, Ribeiro A, Barbosa I

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1281-1293

Published Date: 19 March 2021

The Effect of Rooibos (Aspalathus linearis), Honeybush (Cyclopia intermedia) and Sutherlandia (Lessertia frutescens) on Testicular Insulin Signalling in Streptozotocin-Induced Diabetes in Wistar Rats

Omolaoye TS, Windvogel SL, Du Plessis SS

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1267-1280

Published Date: 19 March 2021

Emodin Ameliorates Renal Damage and Podocyte Injury in a Rat Model of Diabetic Nephropathy via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway

Liu H, Wang Q, Shi G, Yang W, Zhang Y, Chen W, Wan S, Xiong F, Wang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1253-1266

Published Date: 18 March 2021

Comparison Between Pioglitazone/Metformin Combination Therapy and Sitagliptin/Metformin Combination Therapy on the Efficacy in Chinese Type 2 Diabetic Adults Insufficiently Controlled with Metformin: Study Protocol of an Open-Label, Multicenter, Non-Inferiority Parallel-Group Randomized Controlled Trial

Zhang F, Tang L, Li J, Yan Z, Li J, Tong N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1243-1252

Published Date: 18 March 2021

The β3 Adrenergic Receptor Agonist CL316243 Ameliorates the Metabolic Abnormalities of High-Fat Diet-Fed Rats by Activating AMPK/PGC-1α Signaling in Skeletal Muscle

Ding LN, Cheng Y, Xu LY, Zhou LQ, Guan L, Liu HM, Zhang YX, Li RM, Xu JW

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1233-1241

Published Date: 18 March 2021

A Stronger Association of Epicardial Fat Volume with Non-Valvular Atrial Fibrillation Than Measures of General Obesity in Chinese Patients Undergoing Computed Tomography Coronary Angiography

Zhu J, Yang Z, Chen X, Liu J, Zheng L, Zhang L, Pi J, Li G, Zhuang T, Liu C, Wang Y, Liu L, Fan L, Chan P, Tomlinson B, Li Y, Liu Z, Zhang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1223-1232

Published Date: 18 March 2021

Original Research

A Difference Between Bedtime and Pre-Breakfast Plasma Glucose Levels Indicates the Need for Prandial Insulin in Basal Insulin-Treated Type 2 Diabetic Patients with Normal Fasting Glucose

Kress S, Borck A, Zisman A, Bramlage P, Siegmund T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1215-1222

Published Date: 18 March 2021

Original Research

Knowledge and Practice on Diabetic Foot Self-Care and Associated Factors Among Diabetic Patients at Dessie Referral Hospital, Northeast Ethiopia: Mixed Method

Tuha A, Getie Faris A, Andualem A, Ahmed Mohammed S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1203-1214

Published Date: 17 March 2021

Increased Serum GDF15 Related to Improvement in Metabolism by Lifestyle Intervention Among Young Overweight and Obese Adults

Cai L, Li C, Wang Y, Mo Y, Yin J, Ma X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1195-1202

Published Date: 17 March 2021

Silencing of miR-20b-5p Exerts Inhibitory Effect on Diabetic Retinopathy via Inactivation of THBS1 Gene Induced VEGF/Akt/PI3K Pathway

Ma Y, Dong C, Chen X, Zhu R, Wang J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1183-1193

Published Date: 16 March 2021

Determinants and Prevalence of Impotence among Diabetic Patients in Northwestern Hospitals of Nefasit, Eretria

Degavi G, Panari H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1177-1182

Published Date: 16 March 2021

Original Research

Clinical and Metabolic Characteristics of Non-Alcoholic Fatty Liver Disease Patients in Saudi Arabia: Data from the Systematic Observatory Liver Disease (SOLID) Registry

Alswat K, Sanai FM, Al-hamoudi W, Ismail M, Dahlan Y, AlGhamdi HS, Altraif I, Alalwan A, Babatin MMA, Alqahtani SA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1167-1175

Published Date: 16 March 2021

Antihyperglycemic Activity of TLC Isolates from the Leaves of Aloe megalacantha Baker in Streptozotocin-Induced Diabetic Mice

Araya TY, Karim A, Hailu GS, Periasamy G, Kahsay G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1153-1166

Published Date: 15 March 2021

Associations of Metabolic/Obesity Phenotypes with Insulin Resistance and C-Reactive Protein: Results from the CNTR Study

Liao C, Gao W, Cao W, Lv J, Yu C, Wang S, Pang Z, Cong L, Wang H, Wu X, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1141-1151

Published Date: 15 March 2021

Gene Expression Profiling of Apoptotic Proteins in Circulating Peripheral Blood Mononuclear Cells in Type II Diabetes Mellitus and Modulation by Metformin

Al Dubayee M, Alshahrani A, Aljada D, Zahra M, Alotaibi A, Ababtain I, Alnaim M, Alahmari A, Aljarallah A, Elahi MA, Fakhoury HMA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1129-1139

Published Date: 15 March 2021

Adipose Tissue Insulin Resistance is Closely Associated with Metabolic Syndrome in Northern Chinese Populations

Zhang K, Pan H, Wang L, Yang H, Zhu H, Gong F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1117-1128

Published Date: 12 March 2021

The Predictive Value of Visceral Adiposity Index and Lipid Accumulation Index for Microalbuminuria in Newly Diagnosed Type 2 Diabetes Patients

Qi L, Kang N, Li Y, Zhao H, Chen S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1107-1115

Published Date: 11 March 2021

GIP Receptor Antagonist, SKL-14959 Indicated Alteration of the Lipids Metabolism to Catabolism by the Inhibition of Plasma LPL Activity, Resulting in the Suppression of Weight Gain on Diets-Induced Obesity Mice

Nakamura T, Tanimoto H, Okamoto M, Takeuchi M, Tsubamoto Y, Noda H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1095-1105

Published Date: 9 March 2021

Clinical Trial Report

Effectiveness of a WeChat Combined Continuous Flash Glucose Monitoring System on Glycemic Control in Juvenile Type 1 Diabetes Mellitus Management: Randomized Controlled Trial

Xu Y, Xu L, Zhao W, Li Q, Li M, Lu W, Zeng H, Yan J, Yang D, Wu W, Weng J, Pan J, Liu F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1085-1094

Published Date: 9 March 2021

Factors to Consider When Determining Whether Lipotoxicity Solely Causes B-Cell Decompensation in KPT2D [Letter]

Geltser D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1083-1084

Published Date: 9 March 2021

A High Incidence of Metabolic Syndrome Traits in Mexicans Points at Obesity-Related Metabolic Dysfunction

Bello-Chavolla OY, Vargas-Vázquez A, Antonio-Villa NE, Del Razo-Olvera FM, Elías-López D, Aguilar-Salinas CA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1073-1082

Published Date: 9 March 2021

Interaction of General or Central Obesity and Hypertension on Diabetes: Sex-Specific Differences in a Rural Population in Northeast China

Chen MQ, Shi WR, Wang HY, Li Z, Guo XF, Sun YX

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1061-1072

Published Date: 9 March 2021

Double-Blind Controlled Trial of Vitamin E Effects on Serum Lipid Profile in Menopausal Women

Rezasoltani P, Elliyoun N, Ziaie T, Sobhani A, Kazemnezhjad Leyli E, Kazemi Aski S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1053-1060

Published Date: 9 March 2021

Association Between Body Mass Index and Male Sperm Apoptosis and Apoptosis-Related Factors

Zhu G, Zhang Y, Dong J, Liu Y, Zhao F, Li T, Shi Z, Zhang Y, Song N, Song W, Lv Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1043-1051

Published Date: 9 March 2021

Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice

Zhai M, Yan X, Liu J, Long Z, Zhao S, Li W, Liu Y, Hai C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1035-1042

Published Date: 8 March 2021

Islet Autoantibodies in the Patients with Sjogren’s Syndrome and Thyroid Disease and Risk of Progression to Latent Autoimmune Diabetes in Adults: A Case Series

Wen S, Jiang W, Zhou L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1025-1033

Published Date: 5 March 2021

Prevalence and Correlates of Cardio-Metabolic Risk Factors Among Regular Street Food Consumers in Dar es Salaam, Tanzania

B Kagaruki G, J Mahande M, D Kimaro G, S Ngadaya E, Mayige T M, Selemani M, Jaacks LM, Jaffar S, Mfinanaga SG, Bonfoh B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1011-1024

Published Date: 5 March 2021

Metabolomic Signature Between Metabolically Healthy Overweight/Obese and Metabolically Unhealthy Overweight/Obese: A Systematic Review

Cheng D, Zhao X, Yang S, Cui H, Wang G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:991-1010

Published Date: 4 March 2021

Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers

He Y, Wu N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:983-990

Published Date: 3 March 2021

Hepatic Knockdown of Endothelin Type A Receptor (ETAR) Ameliorates Hepatic Insulin Resistance and Hyperglycemia Through Suppressing p66Shc-Mediated Mitochondrial Fragmentation in High-Fat Diet-Fed Mice

Feng L, Wang S, Chen F, Zhang C, Wang Q, Zhao Y, Zhang Z

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:963-981

Published Date: 2 March 2021

Risk Factors Screening for Gestational Diabetes Mellitus Heterogeneity in Chinese Pregnant Women: A Case–Control Study

Wang N, Peng Y, Wang L, Song L, Sun B, Wei J, Wang T, Mi Y, Cui W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:951-961

Published Date: 2 March 2021

Original Research

Effects of Orlistat/Phentermine versus Phentermine on Vascular Endothelial Cell Function in Obese and Overweight Adults: A Randomized, Double-Blinded, Placebo-Controlled Trial

Kwon YJ, Lee H, Nam CM, Chang HJ, Yoon YR, Lee HS, Lee JW

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:941-950

Published Date: 2 March 2021

Effects of Curcumin on High Glucose-Induced Epithelial-to-Mesenchymal Transition in Renal Tubular Epithelial Cells Through the TLR4-NF-κB Signaling Pathway

Liu X, Zhang X, Cai X, Dong J, Chi Y, Chi Z, Gu HF

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:929-940

Published Date: 2 March 2021

Determinants of Dietary Adherence Among Type 2 Diabetes Patients Aimed COVID-19 at the University of Gondar Comprehensive Specialized Hospital

Mekonnen CK, Ferede YM, Abate HK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:917-927

Published Date: 2 March 2021

Magnitude of Overweight and Obesity and Associated Factors Among Public and Private Secondary School Adolescent Students in Mekelle City, Tigray Region, Ethiopia, 2019: Comparative Cross-Sectional Study

Andargie M, Gebremariam K, Hailu T, Addisu A, Zereabruk K

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:901-915

Published Date: 2 March 2021

Relationship Between Serum Amyloid A1 (SAA1) Gene Polymorphisms Studies with Obesity in the Saudi Population

Alharbi KK, Alshammary AF, Aljabri OS, Ali Khan I

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:895-900

Published Date: 1 March 2021

Predictive Value of GAD Antibody for Diabetes in Normal Chinese Adults: A Retrospective Cohort Study in China

Li J, Lin S, Deng C, Xu T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:885-893

Published Date: 1 March 2021

Prevalence of Metabolic Syndrome and Factors Associated With It Among Adults of West Gojjam: A Community-Based Cross-Sectional Study

Walle B, Reba K, Debela Y, Tadele K, Biadglegne F, Gutema H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:875-883

Published Date: 26 February 2021

Platelet Indices and Its Association with Microvascular Complications Among Type 2 Diabetes Mellitus Patients in Northeast Ethiopia: A Cross-Sectional Study

Taderegew MM, Woldeamanuel GG, Emeria MS, Tilahun M, Yitbarek GY, Zegeye B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:865-874

Published Date: 25 February 2021

Increased Serum Cystatin C Levels Were Associated with Depressive Symptoms in Patients with Type 2 Diabetes

Huang Y, Huang W, Wei J, Yin Z, Liu H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:857-863

Published Date: 25 February 2021

The Relationship Between Earlier Onset of Natural Menopause and Elevated Urinary Albumin-Creatinine Ratio in Postmenopausal Chinese Women

Yao M, Liu H, Li B, Liu Y, Mu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:847-856

Published Date: 25 February 2021

A Clinical Epidemiological Analysis of Prognostic Nutritional Index Associated with Diabetic Retinopathy

Yang L, Yu W, Pan W, Chen S, Ye X, Gu X, Hu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:839-846

Published Date: 25 February 2021

lncRNA SNHG17 is Downregulated in Gestational Diabetes Mellitus (GDM) and Has Predictive Values

Li J, Du B, Geng X, Zhou L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:831-838

Published Date: 23 February 2021

Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio Predict Mortality in Patients with Diabetic Foot Ulcers Undergoing Amputations

Chen W, Chen K, Xu Z, Hu Y, Liu Y, Liu W, Hu X, Ye T, Hong J, Zhu H, Shen F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:821-829

Published Date: 24 February 2021

Opportunities for Prevention of Gestational Diabetes Before 24 Weeks of Gestation

Cheng D, Li F, Zhou X, Xu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:813-819

Published Date: 24 February 2021

The Psychometric Properties of General Adherence Scale in Chinese (GAS-C) in Patients with Type 2 Diabetes Using Insulin

Shi Z, Chang J, Ma X, Yin F, Ma M, Li W, Zhu B, Ai Z, Zhao X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:801-811

Published Date: 22 February 2021

No Association Between ADIPOQ or MTHFR Polymorphisms and Gestational Diabetes Mellitus in South African Women

Dias S, Adam S, Rheeder P, Pheiffer C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:791-800

Published Date: 24 February 2021

Original Research

Increased Incidence of Pediatric Diabetic Ketoacidosis After COVID-19: A Two-Center Retrospective Study in Korea

Han MJ, Heo JH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:783-790

Published Date: 22 February 2021

Pre-Existing Diabetes Limits Survival Rate After Immune Checkpoint Inhibitor Treatment for Advanced Lung Cancer: A Retrospective Study in Japan

Hisanaga K, Uchino H, Kakisu N, Miyagi M, Yoshikawa F, Sato G, Isobe K, Kishi K, Homma S, Hirose T

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:773-781

Published Date: 22 February 2021

Natural Compound α-PGG and Its Synthetic Derivative 6Cl-TGQ Alter Insulin Secretion: Evidence for Diminishing Glucose Uptake as a Mechanism

Chen X, Daniels NA, Cottrill D, Cao Y, Wang X, Li Y, Shriwas P, Qian Y, Archer MW, Whitticar NB, Jahan I, Nunemaker CS, Guo A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:759-772

Published Date: 24 February 2021

A Case of Severe Diabetic Ketoacidosis Associated with Pembrolizumab Therapy in a Patient with Metastatic Melanoma

Wu L, Li B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:753-757

Published Date: 18 February 2021

Health-Related Quality of Life and Associated Factors Among Type Two Diabetic Patients on Follow-Up in Dessie Comprehensive Specialized Hospital, Dessie, North East Ethiopia, 2020 [Corrigendum]

Girma M, Wodajo S, Ademe S, Edmealem A, W/Selassie Snr M, Mesafint G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:751-752

Published Date: 17 February 2021

Normalized Hand Grip and Back Muscle Strength as Risk Factors for Incident Type 2 Diabetes Mellitus: 16 Years of Follow-Up in a Population-Based Cohort Study

Jeon YJ, Lee SK, Shin C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:741-750

Published Date: 17 February 2021

CircHIPK3 Alleviates High Glucose Toxicity to Human Renal Tubular Epithelial HK-2 Cells Through Regulation of miR-326/miR-487a-3p/SIRT1

Zhuang L, Wang Z, Hu X, Yang Q, Pei X, Jin G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:729-740

Published Date: 17 February 2021

miR-7a Targets Insulin Receptor Substrate-2 Gene and Suppresses Viability and Invasion of Cells in Diabetic Retinopathy Mice via PI3K-Akt-VEGF Pathway

Ji Z, Luo J, Su T, Chen C, Su Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:719-728

Published Date: 16 February 2021

Evaluation of Stress and Associated Biochemical Changes in Patients with Type 2 Diabetes Mellitus and Obesity

Tyagi K, Agarwal NB, Kapur P, Kohli S, Jalali RK

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:705-717

Published Date: 16 February 2021

Letter

Electrodiagnostics or Ultrasound for Diagnosing Diabetic Peripheral Neuropathy [Letter]

Hernandez Fustes OJ, Hernandez Fustes OJ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:703-704

Published Date: 16 February 2021

Evaluation of Anthropometric Indices and Lipid Parameters to Predict Metabolic Syndrome Among Adults in Mexico

Datta Banik S, Pacheco-Pantoja E, Lugo R, Gómez-de-Regil L, Chim Aké R, Méndez González RM, Gutiérrez Solis AL

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:691-701

Published Date: 16 February 2021

Diabetes-Related Distress Among People with Type 2 Diabetes in Ho Chi Minh City, Vietnam: Prevalence and Associated Factors

Huynh G, Tran TT, Do THT, Truong TTD, Ong PT, Nguyen TNH, Pham LA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:683-690

Published Date: 15 February 2021

Overexpression of miR125b Promotes Osteoporosis Through miR-125b-TRAF6 Pathway in Postmenopausal Ovariectomized Rats

Wang G, Zhang L, Yan C, Wang F, Zhang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:671-682

Published Date: 15 February 2021

Obesity and Heath-Carter Somatotyping of 3438 Adults in the Xinjiang Uygur Autonomous Region of China by Multivariate Analysis

Liu X, Li W, Wen Y, Xu G, Zhou G, Qu Q, Hu Y, Saitierding Y, Mohetaer M, Buerlan Y, Zhong X, Xi H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:659-670

Published Date: 15 February 2021

ShengMai-San Attenuates Cardiac Remodeling in Diabetic Rats by Inhibiting NOX-Mediated Oxidative Stress

Lu Y, Zhu S, Wang X, Liu J, Li Y, Wang W, Wang S, Wang F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:647-657

Published Date: 11 February 2021

Doxycycline in Extremely Low Dose Improves Glycemic Control and Islet Morphology in Mice Fed a High-Fat Diet

Chen Y, Chen Y, Wang N, Gu S, Wang M, Fu Y, Wei C, Xu W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:637-646

Published Date: 11 February 2021

Serum Uric Acid Levels and Metabolic Indices in an Obese Population: A Cross-Sectional Study

Li F, Chen S, Qiu X, Wu J, Tan M, Wang M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:627-635

Published Date: 11 February 2021

Comorbidity Profiles among Obese–Diabetic End-Stage Renal Disease Patients: Data from REIN Registry of PACA Region of France

Kakar A, Mouelhi Y, Loundou A, Crémades A, Gentile S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:617-625

Published Date: 11 February 2021

An Integrated Approach Based on Network Pharmacology Combined with Experimental Verification Reveals AMPK/PI3K/Akt Signaling is an Important Way for the Anti-Type 2 Diabetic Activity of Silkworm Excrement

Duan H, Zhang Q, Liu J, Li R, Peng W, Wu C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:601-616

Published Date: 11 February 2021

Magnitude and Associated Factors of Metabolic Syndrome Among Adult Urban Dwellers of Northern Ethiopia

Gebreegziabiher G, Belachew T, Mehari K, Tamiru D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:589-600

Published Date: 10 February 2021

Revisional Surgeries of Laparoscopic Sleeve Gastrectomy

Li S, Jiao S, Zhang S, Zhou J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:575-588

Published Date: 10 February 2021

Review

Emerging Roles of Dipeptidyl Peptidase-4 Inhibitors in Delaying the Progression of Type 1 Diabetes Mellitus

Gurgel Penaforte-Saboia J, Couri CEB, Vasconcelos Albuquerque N, Silva VLL, Bitar da Cunha Olegario N, Oliveira Fernandes V, Montenegro RM Junior

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:565-573

Published Date: 10 February 2021

The Associations Between Vitamin D Receptor BsmI and ApaI Polymorphisms and Obesity in Korean Patients with Type 2 Diabetes Mellitus

Nam SW, Choi J, Jeon HJ, Oh TK, Lee DH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:557-564

Published Date: 10 February 2021

Original Research

Hyperglycemic Crisis Characteristics and Outcome of Care in Adult Patients without and with a History of Diabetes in Tigrai, Ethiopia: Comparative Study

Gebremedhin G, Enqueselassie F, Yifter H, Deyessa N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:547-556

Published Date: 9 February 2021

Self-care Related Knowledge, Attitude, and Practice and Associated Factors Among Patients with Type 2 Diabetes in JMC, Ethiopia

Mekonnen Y, Hussien N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:535-546

Published Date: 5 February 2021

Effects of a Single Oral Megadose of Vitamin D3 on Inflammation and Oxidative Stress Markers in Overweight and Obese Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Pessoa Mamede LCG, de Lima RLFC, Silva AS, Rodrigues Pita JCL, Galdino Gomes NI, de Sena EA, Moraes Nobrega RP, Scarano Alcântara JO, Fontes de Souza JH, Cardoso GA, de Brito Alves JL, Rodrigues Gonçalves MC

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:525-534

Published Date: 4 February 2021

Diabetes Mellitus and Its Associated Factors in Tuberculosis Patients in Maekel Region, Eritrea: Analytical Cross-Sectional Study

Araia ZZ, Mesfin AB, Mebrahtu AH, Tewelde AG, Osman R, Tuumzghi HA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:515-523

Published Date: 4 February 2021

Depression Among Patients with Type 2 Diabetes Mellitus: Prevalence and Associated Factors in Hue City, Vietnam

Tran NMH, Nguyen QNL, Vo TH, Le TTA, Ngo NH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:505-513

Published Date: 4 February 2021

Elevated Serum Triglycerides are Associated with Ketosis-Prone Type 2 Diabetes in Young Individuals

Ye S, Ran H, Zhang H, Wu H, Li W, Du S, Su Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:497-504

Published Date: 4 February 2021

The Impact of Vitamin D in Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study in Patients with Morbid Obesity

Borges-Canha M, Neves JS, Mendonça F, Silva MM, Costa C, Cabral PM, Guerreiro V, Lourenço R, Meira P, Salazar D, Ferreira MJ, Pedro J, Leite AR, von-Hafe M, Vale C, Viana S, Sande A, Belo S, Lau E, Freitas P, Carvalho D

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:487-495

Published Date: 3 February 2021

Presence of Adenovirus-36 DNA in Adipose Tissue of Women: Relationship with Adipocyte Morphology and the Expression of C/EBPβ and HIF-1α

Barrera-Alcocer J, García-Benavides L, Muñoz-Valle JF, de la Cruz-Mosso U, González RA, Luquín S, Alarcón-Romero LDC, Marino-Ortega LA, Matia-Garcia I, Parra-Rojas I

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:477-486

Published Date: 3 February 2021

Anemia among Adult Diabetic Patients Attending a General Hospital in Eastern Ethiopia: a Cross-sectional Study

Tujuba T, Ayele BH, Fage SG, Weldegebreal F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:467-476

Published Date: 2 February 2021

Prevalence of Overweight and Obesity, and Its Associated Factors Among Health-care Workers, Teachers, and Bankers in Arusha City, Tanzania

Zubery D, Kimiywe J, Martin HD

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:455-465

Published Date: 2 February 2021

A Non-Invasive Prediction Model for Non-Alcoholic Fatty Liver Disease in Adults with Type 2 Diabetes Based on the Population of Northern Urumqi, China

Xue M, Yang X, Zou Y, Liu T, Su Y, Li C, Yao H, Wang S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:443-454

Published Date: 2 February 2021

Epigenetic Regulation of PDX-1 in Type 2 Diabetes Mellitus

Liu J, Lang G, Shi J

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:431-442

Published Date: 2 February 2021

Review

Non-Surgical Interventions for Hospitalized Adults with Class II or Class III Obesity: A Scoping Review

Rees M, Collins CE, De Vlieger N, McDonald VM

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:417-429

Published Date: 2 February 2021

Original Research

Impact of Obesity and Its Associated Comorbid Conditions on COVID-19 Presentation

Mehanna O, El Askary A, Ali E, El Esawy B, FathAlla T, Gharib AF

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:409-415

Published Date: 29 January 2021

Association of Metabolic Obesity Phenotypes and Total Testosterone in Chinese Male Population

Liu L, Liu S, Song Q, Luo D, Su Y, Qi X, Wang Q, Ning J, Lv Y, Guan Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:399-408

Published Date: 29 January 2021

Dihydromyricetin Alleviates High Glucose-Induced Oxidative Stress and Apoptosis in Human Retinal Pigment Epithelial Cells by Downregulating miR-34a Expression

Li W, Xiao H

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:387-397

Published Date: 27 January 2021

Plasma Alarin Level and Its Influencing Factors in Obese Newly Diagnosed Type 2 Diabetes Patients

Zhou X, Luo M, Zhou S, Cheng Z, Chen Z, Yu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:379-385

Published Date: 27 January 2021

Review

Overview of Clinical Trials on Type 2 Diabetes Mellitus: A Comprehensive Analysis of the ClinicalTrials.gov Database

Long J, Liang R, Zheng Q, Yuan G, Xin Z, Chen X, Lai F, Liu Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:367-377

Published Date: 26 January 2021

PARP-1 and SIRT-1 are Interacted in Diabetic Nephropathy by Activating AMPK/PGC-1α Signaling Pathway

Zhu H, Fang Z, Chen J, Yang Y, Gan J, Luo L, Zhan X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:355-366

Published Date: 25 January 2021

Obesity and Prediabetes are Jointly Associated with Lipid Abnormalities Among Adolescents: A Cross-Sectional Study

Almari M, Mohammad A, Abubaker J, Ziyab AH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:345-353

Published Date: 22 January 2021

Epigenetic Histone Modifications in the Pathogenesis of Diabetic Kidney Disease

Lu HC, Dai WN, He LY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:329-344

Published Date: 22 January 2021

Progress of Clinical Trials for the Treatment of Gestational Diabetes Mellitus

Chen T, Liu D, Yao X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:315-327

Published Date: 22 January 2021

The Effectiveness of a Self-Efficacy-Focused Structured Education Program (SSEP) in Improving Metabolic Control and Psychological Outcomes of Type 2 Diabetes Patients: A 12-Month Follow-Up of a Multicenter Randomized Controlled Trial

Jiang XJ, Jiang H, Chen Y, Wu XA, Yu XL, Liu L, Li MZ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:305-313

Published Date: 22 January 2021

Correlation Between Daily Energy Intake from Fat with Insulin Resistance in Patients with Polycystic Ovary Syndrome

Zheng X, Chen Y, Ma D, Zhang M, Huang Y, Tong M, Yan B, Lin S, Yan X, Liu C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:295-303

Published Date: 22 January 2021

Original Research

Characteristics of Gut Microbiota in Cerulein-Induced Chronic Pancreatitis

Wu C, Li M, Chen W

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:285-294

Published Date: 25 January 2021

A Differential Study into Body Fat in Healthy and Hypertensive Populations Using Multiple Indexes

Wang R, Wang Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:279-284

Published Date: 20 January 2021

Downregulation of lncRNA EPB41L4A-AS1 Mediates Activation of MYD88-Dependent NF-κB Pathway in Diabetes-Related Inflammation

Wang Z, Liao W, Liu F, Yang T, Xie W, Liao M, Gu D, Zhang Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:265-277

Published Date: 20 January 2021

NDSP 09: Risk Assessment of Pakistani Individual for Diabetes (RAPID) – Findings from Second National Diabetes Survey of Pakistan (NDSP) 2016–2017

Abdul Basit K, Fawwad A, Riaz M, Tahir B, Khalid M, Basit A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:257-263

Published Date: 19 January 2021

Review

Direct and Indirect Effect of Honey as a Functional Food Against Metabolic Syndrome and Its Skeletal Complications

Mohd Ramli ES, Sukalingam K, Kamaruzzaman MA, Soelaiman IN, Pang KL, Chin KY

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:241-256

Published Date: 18 January 2021

Empagliflozin Regulates the AdipoR1/p-AMPK/p-ACC Pathway to Alleviate Lipid Deposition in Diabetic Nephropathy

Zhang Z, Ni L, Zhang L, Zha D, Hu C, Zhang L, Feng H, Wei X, Wu X

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:227-240

Published Date: 18 January 2021

Current Perspectives on the Role of Very-Low-Energy Diets in the Treatment of Obesity and Type 2 Diabetes in Youth

Gow ML, Pham-Short A, Jebeile H, Varley BJ, Craig ME

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:215-225

Published Date: 18 January 2021

Dietary Knowledge, Attitude and Practice (KAP) Among the Family Members of Patients with Type 2 Diabetes Mellitus (T2DM) and Its Influence on the KAP of T2DM Patients

Hu X, Zhang Y, Lin S, Guo X, Yang D, Cai M, Gao L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:205-213

Published Date: 15 January 2021

Impact of Cognitive Impairment on Adherence to Treatment and Self-Care in Patients with Type 2 Diabetes Mellitus

Świątoniowska-Lonc N, Polański J, Tański W, Jankowska-Polańska B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:193-203

Published Date: 15 January 2021

Evaluation of Antihyperglycemic Effect of Extract of Moringa stenopetala (Baker f.) Aqueous Leaves on Alloxan-Induced Diabetic Rats

Woldekidan S, Mulu A, Ergetie W, Teka F, Meressa A, Tadele A, Abebe A, Gemechu W, Gemeda N, Ashebir R, Sileshi M, Tolcha Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:185-192

Published Date: 15 January 2021

Metabolic and Energy Imbalance in Dysglycemia-Based Chronic Disease

Kalra S, Unnikrishnan AG, Baruah MP, Sahay R, Bantwal G

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:165-184

Published Date: 15 January 2021

miR-129-3p Targeting of MCU Protects Against Glucose Fluctuation-Mediated Neuronal Damage via a Mitochondrial-Dependent Intrinsic Apoptotic Pathway

Wang B, Li Y, You C

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:153-163

Published Date: 15 January 2021

Review

Application of High-Resolution Ultrasound on Diagnosing Diabetic Peripheral Neuropathy

Huang H, Wu S

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:139-152

Published Date: 14 January 2021

Caregivers’ Nutrition Knowledge and Dietary Intake of Type 1 Diabetic Children Aged 3–14 Years in Uganda

Ndahura NB, Munga J, Kimiywe J, Mupere E

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:127-137

Published Date: 14 January 2021

The Association Between Hyperlipidemia and In-Hospital Outcomes in Takotsubo Cardiomyopathy

Li P, Lu X, Teng C, Hadley M, Cai P, Dai Q, Wang B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:117-126

Published Date: 12 January 2021

Immunogenicity and Efficacy of Insulin Glargine Biosimilar Ezelin versus Originator Insulin Glargine in Patients with Type 2 Diabetes

Tarigan TJE, Dwijayanti A, Setyowati S, Louisa M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:107-116

Published Date: 12 January 2021

Association Between Low Serum Testosterone and the Development of Metabolic Syndrome in Elderly Taiwanese Men

Zhong SR, Yang HH, Liao CH, Yang DH, Tu SK, Hung CL, Liao CC

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:99-106

Published Date: 11 January 2021

Metabolic Control and Determinants Among HIV-Infected Type 2 Diabetes Mellitus Patients Attending a Tertiary Clinic in Botswana

Rwegerera GM, Shailemo DHP, Pina Rivera Y, Mokgosi KO, Bale P, Oyewo TA, Luis BD, Habte D, Godman B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:85-97

Published Date: 11 January 2021

Review

Adipogenesis as a Potential Anti-Obesity Target: A Review of Pharmacological Treatment and Natural Products

Jakab J, Miškić B, Mikšić S, Juranić B, Ćosić V, Schwarz D, Včev A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:67-83

Published Date: 8 January 2021

Original Research

A Questionnaire-Based Assessment of Hunger, Speed of Eating and Food Intake in Children with Obesity

Slyper A, Shenker J, Israel A

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:59-66

Published Date: 8 January 2021

Hyperosmolarity Deserves More Attention in Critically Ill COVID-19 Patients with Diabetes: A Cohort-Based Study

Gou L, Xiang M, Ran X, Wang F, Zhang S, Li S, Dong K, Chen X, Huang Y, Meng C, Fan Q, Yang Y, Yu X, Ma D, Yin P

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:47-58

Published Date: 7 January 2021

The Magnitude of Diabetes Mellitus in Adult Hypertensive Patients in Northeast Ethiopia

Wuhib Shumye M, Tegegne B, Ademe S, Workneh M, Abera M, Nemera G, Balcha F

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:37-45

Published Date: 6 January 2021

Association Between CDKAL1, HHEX, CDKN2A/2B and IGF2BP2 Gene Polymorphisms and Susceptibility to Type 2 Diabetes in Uttarakhand, India

Verma AK, Goyal Y, Bhatt D, Beg MMA, Dev K, Alsahli MA, Rahmani AH

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:23-36

Published Date: 6 January 2021

A Rare Potential Pathogenic Variant in the BDNF Gene is Found in a Brazilian Patient with Severe Childhood-Onset Obesity

da Fonseca ACP, Abreu GM, Palhinha L, Zembrzuski VM, Campos Junior M, Carneiro JRI, Nogueira Neto JF, Magno FCCM, Rosado EL, Maya-Monteiro CM, Cabello GMK, Cabello PH, Bozza PT

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:11-22

Published Date: 6 January 2021

Self-Care Practice and Associated Factors Among People Living with Type 2 Diabetes in Addis Ababa, Ethiopia: A Facility-Based Cross-Sectional Study

Wolderufael M, Dereje N

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2021, 14:1-9

Published Date: 6 January 2021

Association Between Single Nucleotide Polymorphisms in CDKAL1 and HHEX and Type 2 Diabetes in Chinese Population

Li C, Shen K, Yang M, Yang Y, Tao W, He S, Shi L, Yao Y, Li Y

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5113-5123

Published Date: 5 January 2021

Potential Role and Excretion Level of Urinary Transferrin, KIM-1, RBP, MCP-1 and NGAL Markers in Diabetic Nephropathy

Siddiqui K, Joy SS, George TP, Mujammami M, Alfadda AA

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5103-5111

Published Date: 31 December 2020

Interactive Effect of IGF2BP2 rs4402960 Variant, Smoking and Type 2 Diabetes

Nfor ON, Ndzinisa NB, Tsai MH, Hsiao CH, Liaw YP

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5097-5102

Published Date: 30 December 2020

Original Research

Discrimination of Chronic Kidney Disease and Diabetic Nephropathy and Analysis of Their Related Influencing Factors

Liu X, Guo Y, Wu J, Yao N, Wang H, Li B

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5085-5096

Published Date: 30 December 2020

Comparison of Coronary Heart Disease and Stroke in Association with Diabetic Retinopathy in Adults with Diabetes Using a National Survey

Yang GR, Li D, Li L

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5079-5084

Published Date: 23 December 2020

Original Research

Knowledge, Attitudes, and Practices Regarding Diabetes Mellitus Among University Students in Jeddah, Saudi Arabia

Gazzaz ZJ

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5071-5078

Published Date: 23 December 2020

Association of Daily Home-Based Hot Water Bathing and Glycemic Control in Ambulatory Japanese Patients with Type 2 Diabetes Mellitus During the COVID-19 Pandemic: A Multicenter Cross-Sectional Study

Kamioka H, Mori Y, Horiuchi T, Hayashi T, Ohmura K, Yamaguchi S, Kato M

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5059-5069

Published Date: 22 December 2020

The Association and Interaction of Aldehyde Dehydrogenase 2 Polymorphisms with Food Group Intake and Probability of Having Non-Alcoholic Fatty Liver Disease

Hao X, Zeng Q

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5049-5057

Published Date: 22 December 2020

Circulating miR-30a-5p and miR-182-5p in Prediabetes and Screen-Detected Diabetes Mellitus

Weale CJ, Matshazi DM, Davids SFG, Raghubeer S, Erasmus RT, Kengne AP, Davison GM, Matsha TE

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020, 13:5037-5047

Published Date: 21 December 2020

Nomogram Based on Risk Factors for Type 2 Diabetes Mellitus Patients with Coronary Heart Disease

Shi R, Wu B, Niu Z, Sun H, Hu F