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Cytomegalovirus retinitis after central retinal vein occlusion in a patient on systemic immunosuppression: does venooclusive disease predispose to cytomegalovirus retinitis in patients already at risk?

Authors Welling J, Tarabishy, Christoforidis J

Received 9 November 2011

Accepted for publication 28 December 2011

Published 19 April 2012 Volume 2012:6 Pages 601—603

DOI https://doi.org/10.2147/OPTH.S28086

Review by Single-blind

Peer reviewer comments 2


John D Welling, Ahmad B Tarabishy, John Christoforidis
Department of Ophthalmology, Havener Eye Institute, Ohio State University, Columbus, OH, USA

Abstract: Cytomegalovirus (CMV) retinitis remains the most common opportunistic ocular infection in immunocompromised patients. Patients with immunocompromising diseases, such as acquired immunodeficiency syndrome, inherited immunodeficiency states, malignancies, and those on systemic immunosuppressive therapy, are known to be at risk. Recently, it has been suggested that patients undergoing intravitreal injection of immunosuppressive agents may also be predisposed. One previous case report speculated that there may be an additional risk for CMV retinitis in acquired immunodeficiency syndrome patients with venoocclusive disease. This case study presents a case of CMV retinitis following central retinal vein occlusion in a patient on systemic immunosuppressants.

Keywords: cytomegalovirus retinitis, central retinal vein occlusion, immunosuppression, solid organ transplant, venous stasis, risk factor

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