Current treatment options for the management of patent ductus arteriosus
Received 24 December 2012
Accepted for publication 12 February 2013
Published 26 March 2013 Volume 2013:4 Pages 23—27
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 5
Koh Takeuchi,1 Atsushi Hirota,2 Sachito Minegishi,1 Jotaro Kobayashi,1 Keiji Tsuchiya3
1Division of Cardiovascular Surgery, 2Department of Neonatology, 3Department of Pediatrics, Japanese Red Cross Medical Center, Shibuya, Tokyo, Japan
Abstract: Pharmacological and/or surgical closure of a hemodynamically significant patent ductus arteriosus (PDA) in the very premature infant has been the standard of care over the past few decades. However, the rationale for closure of PDA has recently been challenged. In this article, three ways of approaching the closure of PDA including pharmacological treatment, catheter intervention, and surgical intervention, are reviewed in detail. In addition, the different treatment strategies applied in clinical care are evaluated with a focus on the discussion of the available evidence of PDA treatment in the literature.
Keywords: patent ductus arteriosus, premature infant, treatment option
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