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Current treatment options for the management of esophageal cancer

Authors Mawhinney M, Glasgow R

Received 25 June 2012

Accepted for publication 20 August 2012

Published 2 November 2012 Volume 2012:4 Pages 367—377

DOI https://doi.org/10.2147/CMAR.S27593

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4


Mark R Mawhinney, Robert E Glasgow

Department of Surgery, Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA

Abstract: In recent years, esophageal cancer characteristics and management options have evolved significantly. There has been a sharp increase in the frequency of esophageal adenocarcinoma and a decline in the frequency of squamous cell carcinoma. A more comprehensive understanding of prognostic factors influencing outcome has also been developed. This has led to more management options for esophageal cancer at all stages than ever before. A multidisciplinary, team approach to management in a high volume center is the preferred approach. Each patient should be individually assessed based on type of cancer, local or regional involvement, and his or her own functional status to determine an appropriate treatment regimen. This review will discuss management of esophageal cancer relative to disease progression and patient functional status.

Keywords: esophageal adenocarcinoma, squamous cell carcinoma, treatment regimen, disease progression, patient functional status

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