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Current strategies for the prevention and management of central line-associated bloodstream infections

Authors Han Z, Liang SY, Marschall J

Published 23 November 2010 Volume 2010:3 Pages 147—163

DOI https://doi.org/10.2147/IDR.S10105

Review by Single-blind

Peer reviewer comments 2

Zhuolin Han, Stephen Y Liang, Jonas Marschall
Division of Infectious Diseases, Washington University School of Medicine in St Louis, St Louis, MO, USA

Abstract: Central venous catheters are an invaluable tool for diagnostic and therapeutic purposes in today’s medicine, but their use can be complicated by bloodstream infections (BSIs). While evidence-based preventive measures are disseminated by infection control associations, the optimal management of established central line-associated BSIs has been summarized in infectious diseases guidelines. We prepared an overview of the state-of-the-art of prevention and management of central line-associated BSIs and included topics such as the role of antibiotic-coated catheters, the role of catheter removal in the management, and a review of currently used antibiotic compounds and the duration of treatment.

Keywords: central venous catheters, bloodstream infections, guidelines, prevention

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