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Current perspective on emergence, diagnosis and drug resistance in Candida auris

Authors Sarma S, Upadhyay S

Received 20 January 2017

Accepted for publication 25 March 2017

Published 7 June 2017 Volume 2017:10 Pages 155—165

DOI https://doi.org/10.2147/IDR.S116229

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Akshita Wason

Peer reviewer comments 2

Editor who approved publication: Professor Suresh Antony

Smita Sarma, Shalini Upadhyay

Department of Microbiology, Medanta – The Medicity, Gurgaon, Haryana, India

Abstract: Candida auris is an emerging fungus that presents a serious threat to global health. The organism is difficult to identify using conventional biochemical methods. C. auris has also attracted attention because of its reduced susceptibility to azoles, polyenes, and echinocandins, with a few strains even resistant to all three classes of antifungals. In this review paper we discuss the trends in emergence of C. auris in different parts of the world, associated risk factors, drug resistance, and diagnostic challenges. Strategies for prevention and therapeutic options for such infections is also addressed.

Keywords: Candidemia, Candida haemulonii, outbreak, drug resistance

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